PDB Information

PDB5CZV
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Bernasconi-Elias, P., Hu, T., Jenkins, D., Firestone, B., Gans, S., Kurth, E., Capodieci, P., Deplazes-Lauber, J., Petropoulos, K., Thiel, P., Ponsel, D., Hee Choi, S., LeMotte, P., London, A., Goetcshkes, M., Nolin, E., Jones, M.D., Slocum, K., Kluk, M.J., Weinstock, D.M., Christodoulou, A., Weinberg, O., Jaehrling, J., Ettenberg, S.A., Buckler, A., Blacklow, S.C., Aster, J.C., Fryer, C.J.
Oncogene
HeaderImmune System
Released2015-08-01
Resolution3.190
CATH Insert Date19 Jun, 2016

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2016 Chopped
H 20 Jun, 2016 Chopped
L 20 Jun, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5czvA01 13 Jul, 2016 3.30.300.320 Assigned
5czvA02 13 Jul, 2016 3.30.70.3310 Assigned
5czvH01 13 Jul, 2016 2.60.40.10 Assigned
5czvH02 13 Jul, 2016 2.60.40.10 Assigned
5czvL01 13 Jul, 2016 2.60.40.10 Assigned
5czvL02 13 Jul, 2016 2.60.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM47 NOTC3_HUMAN Homo sapiens Neurogenic locus notch homolog protein 3
CATH-Gene3D is a Global Biodata Core Resource Learn more...