PDB Information

PDB4TZ4
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex
Chamberlain, P.P., Wang, M., Riley, M., Delker, S., Carmel, G., Miller, K., Lopez-Girona, A., Pagarigan, B., Leon, B., Rychak, E., Corral, L., Lopez-Girona, A., Ren, Y., Wang, M., Riley, M., Delker, S., Ito, T., Hideki, A., Mori, T., Handa, H., Hakoshima, T., Daniel, T.O., Miller, K., Cathers, B.E., Carmel, G., Pagarigan, B., Leon, B., Rychak, E., Corral, L., Ren, Y.
To Be Published
HeaderDna Binding Protein/Ligase
Released2014-07-09
Resolution3.010
CATH Insert Date24 Aug, 2014

PDB Images (10)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Aug, 2014 Chopped
C 25 Aug, 2014 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
4tz4A01 04 Jan, 2017 2.130.10.10 Assigned
4tz4A02 04 Jan, 2017 2.130.10.10 Assigned
4tz4A03 04 Jan, 2017 2.130.10.10 Assigned
4tz4A04 04 Jan, 2017 1.10.150.910 Assigned
4tz4C01 30 Jun, 2015 2.170.150.20 Assigned
4tz4C02 30 Jun, 2015 2.30.130.40 Assigned
4tz4C03 30 Jun, 2015 1.20.58.1480 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q96SW2 CRBN_HUMAN Homo sapiens Protein cereblon
Q16531 DDB1_HUMAN Homo sapiens DNA damage-binding protein 1
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