PDB Information

PDB4Q9Z
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of Selective and Orally Bioavailable Protein Kinase C theta (PKC theta ) Inhibitors from a Fragment Hit.
George, D.M., Breinlinger, E.C., Friedman, M., Zhang, Y., Wang, J., Argiriadi, M., Bansal-Pakala, P., Barth, M., Duignan, D.B., Honore, P., Lang, Q., Mittelstadt, S., Potin, D., Rundell, L., Edmunds, J.J.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-05-02
Resolution2.600
CATH Insert Date20 Jul, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 21 Jul, 2014 Chopped
B 21 Jul, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4q9zA01 03 Aug, 2014 3.30.200.20 Assigned
4q9zA02 03 Aug, 2014 1.10.510.10 Assigned
4q9zB01 27 Jul, 2014 3.30.200.20 Assigned
4q9zB02 27 Jul, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q04759 KPCT_HUMAN Homo sapiens Protein kinase C theta type
Q04759 KPCT_HUMAN Homo sapiens Protein kinase C theta type