PDB 4nee

PDB Links
Overview

PDB Information

PDB	4NEE
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Rattus norvegicus
Primary Citation	How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4. Ren, X., Park, S.Y., Bonifacino, J.S., Hurley, J.H. Elife
Header	Viral Protein/Protein Transport
Released	2013-10-29
Resolution	2.880
CATH Insert Date	02 Feb, 2014

PDB Images (25)

4nee

PDB 4nee

4neeA

PDB Chain 4neeA

4neeB

PDB Chain 4neeB

4neeC

PDB Chain 4neeC

4neeD

PDB Chain 4neeD

4neeE

PDB Chain 4neeE

4neeF

PDB Chain 4neeF

4neeG

PDB Chain 4neeG

4neeH

PDB Chain 4neeH

4neeI

PDB Chain 4neeI

4neeJ

PDB Chain 4neeJ

4neeK

PDB Chain 4neeK

4neeL

PDB Chain 4neeL

4neeA00

CATH Domain 4neeA00

4neeB00

CATH Domain 4neeB00

4neeC00

CATH Domain 4neeC00

4neeD00

CATH Domain 4neeD00

4neeE00

CATH Domain 4neeE00

4neeF00

CATH Domain 4neeF00

4neeG00

CATH Domain 4neeG00

4neeH00

CATH Domain 4neeH00

4neeI00

CATH Domain 4neeI00

4neeJ00

CATH Domain 4neeJ00

4neeK00

CATH Domain 4neeK00

4neeL00

CATH Domain 4neeL00

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	03 Feb, 2014	Chopped
B	03 Feb, 2014	Chopped
C	03 Feb, 2014	Chopped
D	03 Feb, 2014	Chopped
E	03 Feb, 2014	Chopped
F	03 Feb, 2014	Chopped
G	03 Feb, 2014	Chopped
H	03 Feb, 2014	Chopped
I	03 Feb, 2014	Chopped
J	03 Feb, 2014	Chopped
K	03 Feb, 2014	Chopped
L	03 Feb, 2014	Chopped

CATH Domains (12)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4neeA00	15 May, 2014	1.25.10.10	Assigned
4neeB00	15 May, 2014	1.25.10.10	Assigned
4neeC00	07 Mar, 2014	3.30.62.10	Assigned
4neeD00	07 Mar, 2014	3.30.450.60	Assigned
4neeE00	07 Mar, 2014	3.30.62.10	Assigned
4neeF00	07 Mar, 2014	3.30.450.60	Assigned
4neeG00	15 May, 2014	1.25.10.10	Assigned
4neeH00	07 Mar, 2014	3.30.62.10	Assigned
4neeI00	07 Mar, 2014	3.30.450.60	Assigned
4neeJ00	15 May, 2014	1.25.10.10	Assigned
4neeK00	07 Mar, 2014	3.30.62.10	Assigned
4neeL00	07 Mar, 2014	3.30.450.60	Assigned

UniProtKB Entries (12)

Accession	Gene ID	Taxon	Description
P04601	NEF_HV1H2	HIV-1 M:B_HXB2R	Protein Nef
P62744	AP2S1_RAT	Rattus norvegicus	AP-2 complex subunit sigma
P62744	AP2S1_RAT	Rattus norvegicus	AP-2 complex subunit sigma
P62744	AP2S1_RAT	Rattus norvegicus	AP-2 complex subunit sigma
P18484	AP2A2_RAT	Rattus norvegicus	AP-2 complex subunit alpha-2
P04601	NEF_HV1H2	HIV-1 M:B_HXB2R	Protein Nef
P18484	AP2A2_RAT	Rattus norvegicus	AP-2 complex subunit alpha-2
P62744	AP2S1_RAT	Rattus norvegicus	AP-2 complex subunit sigma
P04601	NEF_HV1H2	HIV-1 M:B_HXB2R	Protein Nef
P04601	NEF_HV1H2	HIV-1 M:B_HXB2R	Protein Nef
P18484	AP2A2_RAT	Rattus norvegicus	AP-2 complex subunit alpha-2
P18484	AP2A2_RAT	Rattus norvegicus	AP-2 complex subunit alpha-2