CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.25 | Alpha Horseshoe |
|
1.25.10 | Leucine-rich Repeat Variant |
|
1.25.10.10 | Leucine-rich Repeat Variant |
Domain Context
CATH Clusters
| Superfamily | Leucine-rich Repeat Variant |
| Functional Family | AP-2 complex subunit alpha |
Enzyme Information
UniProtKB Entries (2)
| P18484 |
AP2A2_RAT
Rattus norvegicus
AP-2 complex subunit alpha-2
|
| P04601 |
NEF_HV1H2
HIV-1 M:B_HXB2R
Protein Nef
|
PDB Structure
| PDB | 4NEE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Elife
|