PDB Information

PDB4HSG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors.
Liu, F., Li, F., Ma, A., Dobrovetsky, E., Dong, A., Gao, C., Korboukh, I., Liu, J., Smil, D., Brown, P.J., Frye, S.V., Arrowsmith, C.H., Schapira, M., Vedadi, M., Jin, J.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-10-30
Resolution2.300
CATH Insert Date30 Dec, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 31 Dec, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hsgA01 02 Jan, 2013 3.40.50.150 Assigned
4hsgA02 02 Jan, 2013 2.70.160.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60678 ANM3_HUMAN Homo sapiens Protein arginine N-methyltransferase 3
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