PDB Information

PDB4GMX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.
Lapalombella, R., Sun, Q., Williams, K., Tangeman, L., Jha, S., Zhong, Y., Goettl, V., Mahoney, E., Berglund, C., Gupta, S., Farmer, A., Mani, R., Johnson, A.J., Lucas, D., Mo, X., Daelemans, D., Sandanayaka, V., Shechter, S., McCauley, D., Shacham, S., Kauffman, M., Chook, Y.M., Byrd, J.C.
Blood
HeaderProtein Transport/Inhibitor
Released2012-08-16
Resolution2.100
CATH Insert Date04 Nov, 2012

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4gmxA00 25 Apr, 2013 3.40.50.300 Assigned
4gmxB00 10 Nov, 2012 2.30.29.30 Assigned
4gmxC00 28 Aug, 2013 Holding pen

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P41920 YRB1_YEAST Saccharomyces cerevisiae S288C Ran-specific GTPase-activating protein 1
P62826 RAN_HUMAN Homo sapiens GTP-binding nuclear protein Ran
P30822 XPO1_YEAST Saccharomyces cerevisiae S288C Exportin-1
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