PDB 2xtj

PDB Links
Overview

PDB Information

PDB	2XTJ
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	A Pcsk9-Binding Antibody that Structurally Mimics the Egf(A) Domain of Ldl-Receptor Reduces Ldl Cholesterol in Vivo. Ni, Y.G., Di Marco, S., Condra, J.H., Peterson, L.B., Wang, W., Wang, F., Pandit, S., Hammond, H.A., Rosa, R., Cummings, R.T., Wood, D.D., Liu, X., Bottomley, M.J., Shen, X., Cubbon, R.M., Wang, S.P., Johns, D.G., Volpari, C., Hamuro, L., Chin, J., Huang, L., Zhao, J.Z., Vitelli, S., Haytko, P., Wisniewski, D., Mitnaul, L.J., Sparrow, C.P., Hubbard, B., Carfi, A., Sitlani, A. J.Lipid Res.
Header	Hydrolase/Antibody
Released	2010-10-10
Resolution	2.700
CATH Insert Date	07 Nov, 2010

PDB Images (13)

Image of CATH 2xtj

2xtj

PDB 2xtj

Image of CATH 2xtjA

2xtjA

PDB Chain 2xtjA

Image of CATH 2xtjB

2xtjB

PDB Chain 2xtjB

Image of CATH 2xtjC

2xtjC

PDB Chain 2xtjC

Image of CATH 2xtjD

2xtjD

PDB Chain 2xtjD

Image of CATH 2xtjE

2xtjE

PDB Chain 2xtjE

Image of CATH 2xtjP

2xtjP

PDB Chain 2xtjP

Image of CATH 2xtjA00

2xtjA00

CATH Domain 2xtjA00

Image of CATH 2xtjB00

2xtjB00

CATH Domain 2xtjB00

Image of CATH 2xtjC00

2xtjC00

CATH Domain 2xtjC00

Image of CATH 2xtjD00

2xtjD00

CATH Domain 2xtjD00

Image of CATH 2xtjE00

2xtjE00

CATH Domain 2xtjE00

Image of CATH 2xtjP01

2xtjP01

CATH Domain 2xtjP01

PDB Prints

PDB Chains (6)

Chain ID	Date inserted into CATH	CATH Status
A	07 Nov, 2010	Chopped
B	07 Nov, 2010	Chopped
C	07 Nov, 2010	Chopped
D	07 Nov, 2010	Chopped
E	07 Nov, 2010	Chopped
P	07 Nov, 2010	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2xtjA00	29 Jan, 2013	3.40.50.200	Assigned
2xtjB00	16 Feb, 2011	2.60.40.10	Assigned
2xtjC00	18 Mar, 2013	2.60.40.10	Assigned
2xtjD00	17 Feb, 2011	2.60.40.10	Assigned
2xtjE00	18 Mar, 2013	2.60.40.10	Assigned
2xtjP01	04 Feb, 2013	3.30.70.80	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9