PDB Information

PDB2HVX
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase.
Greco, M.N., Hawkins, M.J., Powell, E.T., Almond, H.R., de Garavilla, L., Hall, J., Minor, L.K., Wang, Y., Corcoran, T.W., Di Cera, E., Cantwell, A.M., Savvides, S.N., Damiano, B.P., Maryanoff, B.E.
J.Med.Chem.
HeaderHydrolase
Released2006-07-31
Resolution2.600
CATH Insert Date15 Jun, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Jun, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2hvxA01 13 Jul, 2007 2.40.10.10 Assigned
2hvxA02 13 Jul, 2007 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P23946 CMA1_HUMAN Homo sapiens Chymase