PDB 1mx1
PDB Information
| PDB | 1MX1 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera frugiperda |
| Gene Source | Homo sapiens |
| Primary Citation | Crystal Structure of Human Carboxylesterase 1 Complexed with the Alzheimer's
Drug Tacrine: From Binding Promiscuity to Selective Inhibition
CHEM.BIOL.
|
| Header | Hydrolase |
| Released | 2002-10-01 |
| Resolution | 2.400 |
| CATH Insert Date | 05 Mar, 2006 |
PDB Images (13)
1mx1
PDB 1mx1
1mx1A
PDB Chain 1mx1A
1mx1B
PDB Chain 1mx1B
1mx1C
PDB Chain 1mx1C
1mx1D
PDB Chain 1mx1D
1mx1E
PDB Chain 1mx1E
1mx1F
PDB Chain 1mx1F
1mx1A00
CATH Domain 1mx1A00
1mx1B00
CATH Domain 1mx1B00
1mx1C00
CATH Domain 1mx1C00
1mx1D00
CATH Domain 1mx1D00
1mx1E00
CATH Domain 1mx1E00
1mx1F00
CATH Domain 1mx1F00
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 Mar, 2006 | Chopped |
| B | 05 Mar, 2006 | Chopped |
| C | 05 Mar, 2006 | Chopped |
| D | 05 Mar, 2006 | Chopped |
| E | 05 Mar, 2006 | Chopped |
| F | 05 Mar, 2006 | Chopped |
CATH Domains (6)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 1mx1A00 | 05 Mar, 2006 | 3.40.50.1820 | Assigned |
| 1mx1B00 | 05 Mar, 2006 | 3.40.50.1820 | Assigned |
| 1mx1C00 | 05 Mar, 2006 | 3.40.50.1820 | Assigned |
| 1mx1D00 | 05 Mar, 2006 | 3.40.50.1820 | Assigned |
| 1mx1E00 | 05 Mar, 2006 | 3.40.50.1820 | Assigned |
| 1mx1F00 | 05 Mar, 2006 | 3.40.50.1820 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P23141 | EST1_HUMAN | Homo sapiens | Liver carboxylesterase 1 |
| P23141 | EST1_HUMAN | Homo sapiens | Liver carboxylesterase 1 |
| P23141 | EST1_HUMAN | Homo sapiens | Liver carboxylesterase 1 |
| P23141 | EST1_HUMAN | Homo sapiens | Liver carboxylesterase 1 |
| P23141 | EST1_HUMAN | Homo sapiens | Liver carboxylesterase 1 |
| P23141 | EST1_HUMAN | Homo sapiens | Liver carboxylesterase 1 |
