The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Methylthiotransferase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: tRNA-2-methylthio-N(6)-dimethylallyladenosine synt...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
121 P0AEI1 (/IPI) P0AEI1 (/IPI) P0AEI1 (/IPI) P0AEI1 (/IPI) P0AEI1 (/IPI) P0AEI1 (/IPI) P0AEI1 (/IPI) P0AEI1 (/IPI) P0AEI1 (/IPI) P0AEI1 (/IPI)
(111 more)
N6-isopentenyladenosine methylthiotransferase activity GO:0035597
Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).
121 P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA)
(111 more)
N6-isopentenyladenosine methylthiotransferase activity GO:0035597
Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).
121 P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP)
(111 more)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
121 P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA)
(111 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
121 P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP) P0AEI1 (/IMP)
(111 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
121 P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA) P0AEI1 (/IDA)
(111 more)
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