CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.2300 | THUMP fold |
|
3.30.2300.10 | THUMP superfamily |
Domain Context
CATH Clusters
| Superfamily | THUMP superfamily |
| Functional Family | tRNA(cytosine(8)) deaminase |
Enzyme Information
| 3.5.4.35 |
tRNA(cytosine(8)) deaminase.
based on mapping to UniProt Q8TWU6
Cytosine(8) in tRNA + H(2)O = uracil(8) in tRNA + NH(3).
-!- The enzyme from Methanopyrus kandleri specifically catalyzes the deamimation of cytosine at poition 8 of tRNA in 30 different tRNAs. -!- This cytosine-to-uracil editing guarantees the proper folding and functionality of the tRNAs.
|
UniProtKB Entries (1)
| Q8TWU6 |
CDAT8_METKA
Methanopyrus kandleri AV19
TRNA(cytosine(8)) deaminase
|
PDB Structure
| PDB | 3G8Q |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A cytidine deaminase edits C to U in transfer RNAs in Archaea
Science
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