# STOCKHOLM 1.0 #=GF ID 3.90.228.10/FF/000013 #=GF DE Poly [ADP-ribose] polymerase #=GF AC 3.90.228.10/FF/000013 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 78.684 #=GS Q9UKK3/379-567 AC Q9UKK3 #=GS Q9UKK3/379-567 OS Homo sapiens #=GS Q9UKK3/379-567 DE Protein mono-ADP-ribosyltransferase PARP4 #=GS Q9UKK3/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS Q9UKK3/379-567 DR GO; GO:0003677; GO:0003950; GO:0005515; GO:0005634; GO:0005737; GO:0005829; GO:0005876; GO:0006281; GO:0006464; GO:0006471; GO:0006954; GO:0006974; GO:0008219; GO:0016020; GO:0019899; GO:0042493; GO:0051972; GO:0070062; GO:0140289; GO:1990404; GO:1990904; #=GS E9PYK3/372-559 AC E9PYK3 #=GS E9PYK3/372-559 OS Mus musculus #=GS E9PYK3/372-559 DE Protein mono-ADP-ribosyltransferase PARP4 #=GS E9PYK3/372-559 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS E9PYK3/372-559 DR GO; GO:0003950; GO:0005634; GO:0005737; GO:0005819; GO:0005829; GO:0005876; GO:0006464; GO:0006954; GO:0008219; GO:0019899; GO:0051972; GO:0140289; GO:1990404; #=GS Q55GU8/451-644 AC Q55GU8 #=GS Q55GU8/451-644 OS Dictyostelium discoideum #=GS Q55GU8/451-644 DE Poly [ADP-ribose] polymerase #=GS Q55GU8/451-644 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q55GU8/451-644 DR GO; GO:0010225; GO:0010421; GO:0010918; #=GS Q54LJ4/471-701 AC Q54LJ4 #=GS Q54LJ4/471-701 OS Dictyostelium discoideum #=GS Q54LJ4/471-701 DE Poly [ADP-ribose] polymerase #=GS Q54LJ4/471-701 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q54LJ4/471-701 DR GO; GO:0010421; GO:0010918; #=GS B4E2S2/379-567 AC B4E2S2 #=GS B4E2S2/379-567 OS Homo sapiens #=GS B4E2S2/379-567 DE Poly [ADP-ribose] polymerase #=GS B4E2S2/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS Q54HY5/492-675 AC Q54HY5 #=GS Q54HY5/492-675 OS Dictyostelium discoideum #=GS Q54HY5/492-675 DE Poly [ADP-ribose] polymerase #=GS Q54HY5/492-675 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q54HY5/492-675 DR GO; GO:0010421; GO:0010918; #=GS F0ZYT3/452-640 AC F0ZYT3 #=GS F0ZYT3/452-640 OS Dictyostelium purpureum #=GS F0ZYT3/452-640 DE Poly [ADP-ribose] polymerase #=GS F0ZYT3/452-640 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS A0A2K5RNC5/379-567 AC A0A2K5RNC5 #=GS A0A2K5RNC5/379-567 OS Cebus capucinus imitator #=GS A0A2K5RNC5/379-567 DE Poly [ADP-ribose] polymerase #=GS A0A2K5RNC5/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Cebinae; Cebus; Cebus capucinus; Cebus capucinus imitator; #=GS A0A1D5R6M9/379-567 AC A0A1D5R6M9 #=GS A0A1D5R6M9/379-567 OS Macaca mulatta #=GS A0A1D5R6M9/379-567 DE Poly [ADP-ribose] polymerase #=GS A0A1D5R6M9/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta; #=GS A0A2K5HKE3/379-570 AC A0A2K5HKE3 #=GS A0A2K5HKE3/379-570 OS Colobus angolensis palliatus #=GS A0A2K5HKE3/379-570 DE Poly [ADP-ribose] polymerase #=GS A0A2K5HKE3/379-570 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Colobus; Colobus angolensis; Colobus angolensis palliatus; #=GS A0A0D9RZI5/379-567 AC A0A0D9RZI5 #=GS A0A0D9RZI5/379-567 OS Chlorocebus sabaeus #=GS A0A0D9RZI5/379-567 DE Poly [ADP-ribose] polymerase #=GS A0A0D9RZI5/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Chlorocebus; Chlorocebus sabaeus; #=GS G3QKC5/379-567 AC G3QKC5 #=GS G3QKC5/379-567 OS Gorilla gorilla gorilla #=GS G3QKC5/379-567 DE Poly [ADP-ribose] polymerase #=GS G3QKC5/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Gorilla; Gorilla gorilla; Gorilla gorilla gorilla; #=GS A0A096N7T3/379-567 AC A0A096N7T3 #=GS A0A096N7T3/379-567 OS Papio anubis #=GS A0A096N7T3/379-567 DE Poly [ADP-ribose] polymerase #=GS A0A096N7T3/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Papio; Papio anubis; #=GS H2Q7A7/379-567 AC H2Q7A7 #=GS H2Q7A7/379-567 OS Pan troglodytes #=GS H2Q7A7/379-567 DE Poly [ADP-ribose] polymerase #=GS H2Q7A7/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A2K6MBJ5/379-567 AC A0A2K6MBJ5 #=GS A0A2K6MBJ5/379-567 OS Rhinopithecus bieti #=GS A0A2K6MBJ5/379-567 DE Poly [ADP-ribose] polymerase #=GS A0A2K6MBJ5/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus bieti; #=GS A0A2K5MH55/343-531 AC A0A2K5MH55 #=GS A0A2K5MH55/343-531 OS Cercocebus atys #=GS A0A2K5MH55/343-531 DE Poly [ADP-ribose] polymerase #=GS A0A2K5MH55/343-531 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Cercocebus; Cercocebus atys; #=GS A0A2K6A138/379-567 AC A0A2K6A138 #=GS A0A2K6A138/379-567 OS Mandrillus leucophaeus #=GS A0A2K6A138/379-567 DE Poly [ADP-ribose] polymerase #=GS A0A2K6A138/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Mandrillus; Mandrillus leucophaeus; #=GS G7PVV4/379-567 AC G7PVV4 #=GS G7PVV4/379-567 OS Macaca fascicularis #=GS G7PVV4/379-567 DE Poly [ADP-ribose] polymerase #=GS G7PVV4/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GS A0A2R8ZM55/379-567 AC A0A2R8ZM55 #=GS A0A2R8ZM55/379-567 OS Pan paniscus #=GS A0A2R8ZM55/379-567 DE Poly [ADP-ribose] polymerase #=GS A0A2R8ZM55/379-567 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GS A0A2K5HKF0/379-570 AC A0A2K5HKF0 #=GS A0A2K5HKF0/379-570 OS Colobus angolensis palliatus #=GS A0A2K5HKF0/379-570 DE Poly [ADP-ribose] polymerase #=GS A0A2K5HKF0/379-570 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Colobus; Colobus angolensis; Colobus angolensis palliatus; #=GS A0A2K6MBQ1/203-391 AC A0A2K6MBQ1 #=GS A0A2K6MBQ1/203-391 OS Rhinopithecus bieti #=GS A0A2K6MBQ1/203-391 DE Poly [ADP-ribose] polymerase #=GS A0A2K6MBQ1/203-391 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus bieti; #=GF SQ 21 Q9UKK3/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDVLQIFRVGRVNETTEFLSKLGNVRPLLHGSPVQNIV---GILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- E9PYK3/372-559 RCKIEHVDQNTEEFSRVRKEVL--------------------------------QNNRSEQP-----VDILQIFRVGRVNEATEFLSKLGNVRLLFHGSPVRNIL---GILSRGLLLPKVAEDRGVQRTDVGNLGSGIYFSDSLSTSIKYAHAGETDGSRLLVVCDVALGKCVNLFKKDFSLTEAPPGYDSVHGVSETTSVP------------TDFQDDEFVVYKTNQVKMKYIVKFCT----- Q55GU8/451-644 -THIEHLHQASAGYQIFIRNFL--------------------------------SNPHHQKAIDNGEIKILNCYRLDKKLESDNFLD-VGNVQYLYHGSKPQNLV---GLLSRGILPPDYVKQIGGKRTDFGYLGSGIYFSDDVVSS-TYTSPIGEKGSRFIIMSSVSLGKVKEFSKIQPSLQCAPSGHHSCKGLKSTPTNP------------TDFKNNEYVVFNPNQSKLSFLIEY-IENYKK Q54LJ4/471-701 RCQINQLDKSSKDFKRITDQIKGGTKIEGLTQPQQSIKKSNGNDNNNNNENCIDNNNNNNNL-----IKIKNIFKIIRK-EEDNYNFEVGNLKTLYHGSNPSNIL---GILSRGLLTPNVSTSIGAGRRDIGYLGSGIYFGVKPSTSIQYCKASTKTLSKYMFICSVALGQIKKYTTHQTQLSKPPKGFDSVQGVGSSSSSSSSSSSSNNTVKQSDFIDDEIVIYDSKQQKIQYLIEFDD----- B4E2S2/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDVLQIFRVGRVNETTEFLSKLGNVRPLLHGSPVQNIV---GILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- Q54HY5/492-675 -TNLSPLGKYSYDYS-VVKNLL--------------------------------KGVEG--------INDLNIYQIQKEGDVESHSL-QSPSKLLFHGSRASNFV---GILSRGLLLPKVIVNNGGGRTDFGYLGAGIYFGDGFDTALKYAHPSLSNGKRYALVSKVGLGRVSNHLKINSSLTQPPSGFDSCLGIKKNSTNQ------------SDFHDNEYVIYNTNQYRQEYLIEFTFSG--- F0ZYT3/452-640 -TDIRYLHPASSEYKLFMHIFR---------------EKE--------------IHTRNEDF-----IEIVNVFRLEKEKENKNFNESIGNCQYLFHGTNPSNIV---GILSKGLLLPDIITSSGGKRSDFGYLGKGIYFSEDIISSLKFI-PGTSTGTSLIIVSYVALGNVKEYTNLQPELTSPPKGYDSCKGIKS-----------------SDFKHNEHVIYNSNQSKLSYLLEFKINNFNK A0A2K5RNC5/379-567 RCKIEHVEKNTEEFLRVRQEVL--------------------------------QNNHSKSP-----VDILQIFRVGRVNETTEFLSKLGNVRPLLHGSPVRNIV---GILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETEGTRLLLICDVALGKCMDLHKKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- A0A1D5R6M9/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQIFRVGRVIETTEFLSKLGNVRPLLHGSPVRNIV---GILCRGLLLPKVVEDHGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- A0A2K5HKE3/379-570 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQIFRVGRVIETTEFLSKLGNVRPLLHGSPHWAYILSCPSLFRGLLLPKAVEDHGVQRRDVGNLGSGIYFSDSLSTSLKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSLTEAPPGYDSVHGLSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- A0A0D9RZI5/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQIFRVGRVIETTEFLSKLGNVRPLLHGSPVRNIV---GILCRGLLLPKVVEDHGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- G3QKC5/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDVLQIFRVGRVNETTEFLSKLGNVRPLLHGSPVRNIV---GILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFPMP---- A0A096N7T3/379-567 RCKIEHVEHNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQIFRVGRVIETTEFLSRLGNVRPLLHGSPVRNIV---GILCRGLLLPKVVEDHGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCIDLYKKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- H2Q7A7/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDVLQIFRVGRVNETTEFLSKLGNVRPLLHGSPVRNIV---GILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKNFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIVKFSMP---- A0A2K6MBJ5/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQVFRVGRGIETTEFLSRLGNVRSLLHGSPARNIV---GILCRGLLLPKVVEDHGVQRTDVGNLGSGIYFSDSLSASIKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSFTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- A0A2K5MH55/343-531 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQIFRFGIVNETTEFLSRLGNVRPLLHGSPVRNIV---GILCRGLLLPKAVEDRGVQRTDIGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- A0A2K6A138/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQIFRVGRVIETTEFLSRLGNVRPLLHGSPVRNIV---GILCRGLLLPKVVEDHGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- G7PVV4/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQIFRVGRVIETTEFLSKLGNVRPLLHGSPVRNIV---GILCRGLLLPKVVEDHGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- A0A2R8ZM55/379-567 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDVLQIFRVGRVNETTEFLSKLGNVRPLLHGSPVQNIV---GILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKNFSLTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIVKFSMP---- A0A2K5HKF0/379-570 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQIFRVGRVIETTEFLSKLGNVRPLLHGSPHWAYILSCPSLFRGLLLPKAVEDHGVQRRDVGNLGSGIYFSDSLSTSLKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSLTEAPPGYDSVHGLSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- A0A2K6MBQ1/203-391 RCKIEHVEQNTEEFLRVRKEVL--------------------------------QNHHSKSP-----VDILQVFRVGRGIETTEFLSRLGNVRSLLHGSPARNIV---GILCRGLLLPKVVEDHGVQRTDVGNLGSGIYFSDSLSASIKYSHPGETDGTRLLLICDVALGKCMDLHKKDFSFTEAPPGYDSVHGVSQTASVT------------TDFEDDEFVVYKTNQVKMKYIIKFSMP---- #=GC scorecons 35575665546467346454550000000000000000000000000000000046455433000007566567754632844574435775639599744486700077958979695554539459595959969999664556756844754446565556649699644554545468646949779559654545330000000000006994669597856794854867683430000 #=GC scorecons_70 ___*__*_____**_________________________________________*___________*_*__***__*__*___*____**___*_***___*_*___***_******______*__*_*_*_*********___**_**__*____*_*___**_****___________**_**_****__**___________________***_***_***__**_*__***_*_______ #=GC scorecons_80 ___*_________*___________________________________________________________**_____*________**___*_***___*_____*_*_****_*______*__*_*_*_**_****______*__*__*_____________*_**___________*___*_*_**__*_____________________**___*_***__**_*__*_*_*_______ #=GC scorecons_90 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