# STOCKHOLM 1.0
#=GF ID 3.40.800.20/FF/000020
#=GF DE Histone deacetylase
#=GF AC 3.40.800.20/FF/000020
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 65.000
#=GS E3K8N2/1-386       AC E3K8N2
#=GS E3K8N2/1-386       OS Puccinia graminis f. sp. tritici CRL 75-36-700-3
#=GS E3K8N2/1-386       DE Histone deacetylase 1/2
#=GS E3K8N2/1-386       DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia; Puccinia graminis; 
#=GS M2RX09/1-379       AC M2RX09
#=GS M2RX09/1-379       OS Entamoeba histolytica KU27
#=GS M2RX09/1-379       DE Histone deacetylase
#=GS M2RX09/1-379       DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; 
#=GS A0C993/4-377       AC A0C993
#=GS A0C993/4-377       OS Paramecium tetraurelia
#=GS A0C993/4-377       DE Histone deacetylase
#=GS A0C993/4-377       DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; 
#=GS K2HGR3/1-379       AC K2HGR3
#=GS K2HGR3/1-379       OS Entamoeba nuttalli P19
#=GS K2HGR3/1-379       DE Histone deacetylase
#=GS K2HGR3/1-379       DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba nuttalli; 
#=GS B0E6R0/1-378       AC B0E6R0
#=GS B0E6R0/1-378       OS Entamoeba dispar SAW760
#=GS B0E6R0/1-378       DE Histone deacetylase
#=GS B0E6R0/1-378       DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba dispar; 
#=GS A0A0L6UV79/16-386  AC A0A0L6UV79
#=GS A0A0L6UV79/16-386  OS Puccinia sorghi
#=GS A0A0L6UV79/16-386  DE Histone deacetylase
#=GS A0A0L6UV79/16-386  DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia; Puccinia sorghi; 
#=GS A0A2N5RY30/1-386   AC A0A2N5RY30
#=GS A0A2N5RY30/1-386   OS Puccinia coronata var. avenae f. sp. avenae
#=GS A0A2N5RY30/1-386   DE Uncharacterized protein
#=GS A0A2N5RY30/1-386   DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia; Puccinia coronata; Puccinia coronata var. avenae; 
#=GS A0A180GQB4/1-386   AC A0A180GQB4
#=GS A0A180GQB4/1-386   OS Puccinia triticina 1-1 BBBD Race 1
#=GS A0A180GQB4/1-386   DE Uncharacterized protein
#=GS A0A180GQB4/1-386   DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia; Puccinia triticina; 
#=GS N9TH27/1-379       AC N9TH27
#=GS N9TH27/1-379       OS Entamoeba histolytica HM-1:IMSS-A
#=GS N9TH27/1-379       DE Histone deacetylase
#=GS N9TH27/1-379       DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; 
#=GS Q5U8M9/1-379       AC Q5U8M9
#=GS Q5U8M9/1-379       OS Entamoeba histolytica
#=GS Q5U8M9/1-379       DE Histone deacetylase
#=GS Q5U8M9/1-379       DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; 
#=GS M7WC52/1-379       AC M7WC52
#=GS M7WC52/1-379       OS Entamoeba histolytica HM-3:IMSS
#=GS M7WC52/1-379       DE Histone deacetylase
#=GS M7WC52/1-379       DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; 
#=GS M3UKS4/1-379       AC M3UKS4
#=GS M3UKS4/1-379       OS Entamoeba histolytica HM-1:IMSS-B
#=GS M3UKS4/1-379       DE Histone deacetylase
#=GS M3UKS4/1-379       DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; 
#=GS A0DPM0/23-403      AC A0DPM0
#=GS A0DPM0/23-403      OS Paramecium tetraurelia
#=GS A0DPM0/23-403      DE Histone deacetylase
#=GS A0DPM0/23-403      DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; 
#=GS A0BCV3/4-370       AC A0BCV3
#=GS A0BCV3/4-370       OS Paramecium tetraurelia
#=GS A0BCV3/4-370       DE Uncharacterized protein
#=GS A0BCV3/4-370       DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; 
#=GS A0DGA6/4-361       AC A0DGA6
#=GS A0DGA6/4-361       OS Paramecium tetraurelia
#=GS A0DGA6/4-361       DE Histone deacetylase
#=GS A0DGA6/4-361       DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; 
#=GS A0A2N5VLY4/1-387   AC A0A2N5VLY4
#=GS A0A2N5VLY4/1-387   OS Puccinia coronata var. avenae f. sp. avenae
#=GS A0A2N5VLY4/1-387   DE Uncharacterized protein
#=GS A0A2N5VLY4/1-387   DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia; Puccinia coronata; Puccinia coronata var. avenae; 
#=GF SQ 16
E3K8N2/1-386               -------MPRVAYYYDDDVGAYAYAPHHPMKPHRIKMAHNLILNAGLNQKMDMLCA---------KRATREEMTKFHTDEYICHIAQVNQEDPETLVSGRDKSGDNRFLVGDDCPGFEGLFEFCSISAGGSIAAAKRINSGQADIAINWSGGLHHAKKREASGFCYVNDIVLAILELLRFHSRVLYIDIDIHHGDGVEEAFYTTDRVMTCSFHKFGD-FFPGTGHVGDRGIGKGKGYAVNVPLKTGIDDDTYRSIFRPVINHIMSWYQPGAIVLQCGADSLAEDKLGSFNLSMNGHADCVRHVKSFNVPLVVLGGGGYTIRNVARTWAFETSVCLGPHEELSLADLPYNEYMEYFGPNFKLEVPSN-NMDNHNSLDYLNGILAKVVDSLRDLPFAPSTQRRPLS-
M2RX09/1-379               -------MSRVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKP---------WRATNEQMEMFHSKEYIDFLQRVT---PEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINERAADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAFKATNRVMTFSLHKYGDNYFPGTGDVDEVGIDEGKNYSINVPLKDGINDEGYHRLFYPIIDRIMEVFQPSVVVMQCGADSLNGDRLGFFNLSIQGHCDCMKYVKKFGLPMILVGGGGYTVSNTARCWCYETAAACDLNIPDQIP---INDYLEYYVPDMKITISTNPQMKNCNSRNYIEDILNKVMAILEEV----GNSNLPIVQ
A0C993/4-377               F------KQKVTYYYDEEFGTFNYSTTHPMKPLRVAITDDLVGHYGLKQYMNCIVR-------CINLVDEDVLTQFHSEEYINLIKIIT---PENKCQHEDQ--LYRFNFMEDCPVLDRLFDFCLCQTSGSVGAACVIADQKSNIAINWSGGLHHAKQSEASGFCYVNDCVLGILELLKTYQRVLYIDIDIHHGDGVEEAFYLTDRVMTCSFHKFKE-YFPGTGHIDDIGHDKGKYYAVNFPLNEGLNDDSIQLIFKPVIDSIMENFRPDVVMLQGGTDSLSGDRLGCFNLSIKGHGSCTEYLKKFNVPIIMVGGGGYTLRNVPRCWTYETSLALNVPIPDNIPD--ESDYKIYFGPEYKLHLPIS-NMEEQNSKEYLEKNISQRIQN--KF--EPGCAQ-----
K2HGR3/1-379               -------MSRVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKP---------WRATNEQMEMFHSKEYIDFLQRVT---PEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINERAADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAFKATNRVMTFSLHKYGDNYFPGTGDVDEVGIDEGKNYSINVPLKDGINDEGYHRLFYPIIDRIMEVFQPSVVVMQCGADSLNGDRLGFFNLSIQGHCDCMKYVKKFGLPMILVGGGGYTVSNTARCWCYETAAACDLNIPDQIP---INDYLEYYVPDMKITISTNPQMKNCNSRNYIEDILNKVMAILEEV----GNSNLPIVQ
B0E6R0/1-378               -------MSRVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKP---------WRATNEQMEMFHSKEYIDFLQRVT---PEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINERAADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAFKATNRVMTFSLHKYGDNYFPGTGDVDEIGIDEGKNYSINVPLKDGINDEGYHRLFYPIIDRIMEVFQPSVVVMQCGADSLNGDRLGFFNLSIQGHCDCMKYVKKFGLPMILVGGGGYTVSNTARCWCYETAAACDLNIPDQIP---INDYLEYYVPDMKITISTNPQMKNCNSRNYIEDILNKVMIILEDV----GNSNLPIV-
A0A0L6UV79/16-386          LSLNKQKTNQKSLHSTDDVGAYAYAPHHPMKPHRIKMAHNLILNAGLNKKMDMLTA---------KRATREQMTKFHTDEYICHIAQVNQEDPETLTSGRDKSGDNRFLVGDDCPGFEGLFEFCTISAGGSIAAAKRINSGQADIAINWSGGLHHAKKREASGFCYVNDIVLAILELLRFHSRVLYIDIDIHHGDGVEEAFYTTDRVMTCSFHKFGD-FFPGTGHVGDRGLGKGKGYAVNVPLKTGIDDNTYRSIFRPVINHIMSWYQPGAIVLQCGADSLAEDKLGSFNLSINGHADCVRHVKSFNVPLVVLGGGGYTIRNVARTWAFETSVCLGPHEELSLADLPYNEYMEYFGPNFKLEVPSN-NMDNHNSIDYLNGIL-----------------------
A0A2N5RY30/1-386           -------MPRVAYYYDDDVGAYAYAPHHPMKPHRIKMAHNLILNAGLNKKMDMLTA---------KRATREEMTKFHTDEYICHIAQVNQEEPETLASGRDKSGDNRFLVGDDCPGFEGLFEFCSISAGGSIAAAKRINSGQADIAINWSGGLHHAKKREASGFCYVNDIVLAILELLRFHSRVLYIDIDIHHGDGVEEAFYTTDRVMTCSFHKFGD-FFPGTGHVGDRGLGKGKGYAVNVPLKTGIDDDTYRSIFRPVINHIMSWYQPGAIVLQCGADSLAEDKLGSFNLSMNGHADCVRHVKSFNVPLVVLGGGGYTIRNVARTWAFETSVCLGPHEELSLADLPYNEYMEYFGPNFKLEVPSN-NMDNHNSVDYLNGILEKVVDSLRDLPFAPSTQRRPLS-
A0A180GQB4/1-386           -------MPRVAYYYDDDVGAYAYAPHHPMKPHRIKMAHNLILNAGLNKKMDMLTA---------KRATREEMTKFHTDEYICHIAQVNQEDPETLVSGRDKSGDNRFLVGDDCPGFEGLFEFCSISAGGSIAAAKRINSGQADIAINWSGGLHHAKKREASGFCYVNDIVLAILELLRFHSRVLYIDIDIHHGDGVEEAFYTTDRVMTCSFHKFGD-FFPGTGHVGDRGIGKGKGYAVNVPLKTGIDDDTYRSIFRPVINHIMSWYQPGAIVLQCGADSLAEDKLGSFNLSMNGHADCVRHVKSFNVPLVVLGGGGYTIRNVARTWAFETSVCLGPHEELSLADLPYNEYMEYFGPNFKLEVPSN-NMDNHNSLDYLNGILSKVVDSLRDLPFAPSTQRRPLS-
N9TH27/1-379               -------MSRVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKP---------WRATNEQMEMFHSKEYIDFLQRVT---PEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINERAADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAFKATNRVMTFSLHKYGDNYFPGTGDVDEVGIDEGKNYSINVPLKDGINDEGYHRLFYPIIDRIMEVFQPSVVVMQCGADSLNGDRLGFFNLSIQGHCDCMKYVKKFGLPMILVGGGGYTVSNTARCWCYETAAACDLNIPDQIP---INDYLEYYVPDMKITISTNPQMKNCNSRNYIEDILNKVMAILEEV----GNSNLPIVQ
Q5U8M9/1-379               -------MSRVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKP---------WRATNEQMEMFHSKEYIDFLQRVT---PEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINERAADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAFKATNRVMTFSLHKYGDNYFPGTGDVDEVGIDEGKNYSINVPLKDGINDEGYHRLFYPIIDRIMEVFQPSVVVMQCGADSLNGDRLGFFNLSIQGHCDCMKYVKKFGLPMILVGGGGYTVSNTARCWCYETAAACDLNIPDQIP---INDYLEYYVPDMKITISTNPQMKNCNSRNYIEDILNKVMAILEEV----GNSNLPIVQ
M7WC52/1-379               -------MSRVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKP---------WRATNEQMEMFHSKEYIDFLQRVT---PEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINERAADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAFKATNRVMTFSLHKYGDNYFPGTGDVDEVGIDEGKNYSINVPLKDGINDEGYHRLFYPIIDRIMEVFQPSVVVMQCGADSLNGDRLGFFNLSIQGHCDCMKYVKKFGLPMILVGGGGYTVSNTARCWCYETAAACDLNIPDQIP---INDYLEYYVPDMKITISTNPQMKNCNSRNYIEDILNKVMAILEEV----GNSNLPIVQ
M3UKS4/1-379               -------MSRVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKP---------WRATNEQMEMFHSKEYIDFLQRVT---PEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINERAADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAFKATNRVMTFSLHKYGDNYFPGTGDVDEVGIDEGKNYSINVPLKDGINDEGYHRLFYPIIDRIMEVFQPSVVVMQCGADSLNGDRLGFFNLSIQGHCDCMKYVKKFGLPMILVGGGGYTVSNTARCWCYETAAACDLNIPDQIP---INDYLEYYVPDMKITISTNPQMKNCNSRNYIEDILNKVMAILEEV----GNSNLPIVQ
A0DPM0/23-403              F------KQKVTYYYDEEFGTYNYSTTHPMKPLRVAITDDLVGHYGLKQYMNCIDQ--SFVQTYIKRVDEDVLTQFHSYEYIDLIKIIT---PENKCQYEDQ--LYRFNFMEDCPVLDRLFDFCLCQTSGSVGAACVIADQKSNIAINWSGGLHHAKQSEASGFCYVNDCVLGILELLKTYQRVLYVDIDIHHGDGVEEAFYLTDRVMTCSFHKFKE-YFPGTGHIDDVGHDKGKYYAVNFPLNEGLNDDSIQHIFKPVIDKIMENFRPDVVMLQGGTDSLSGDRLGCFNLSIKGHGTCIEYLKKFNVPIIMVGGGGYTLRNVPRCWTYETSLALNVPIQDNIPD--ESEYKVYFGPEYKLHLPIS-NMEEQNSKDYLEKNIVQILENLKQI--TPGCAQ-----
A0BCV3/4-370               F------KQNVTYYYDEEFGTYNYSTTHPMKPLRVAITDDLVGHYGLKQYMNCIDQ--SFVQTYIKRVDEDVLTQFHSYEYIDLIKIIT---PENKCQYEDQ--LYRFNFMEDCPVLDRLFDFCLCQTSGSVGAACVIADQKSNIAINWSGGLHHAKQSEASGFCYVNDCVLGILELLKTYQRVLYVDIDIHHGDGVEEAFYLTDRVMTCSFHKFKE-YFPGTGHIDDVGHDKGKYYAVNFPLNEGLNDDSIQYIFKPVIDKIMENFRPDVVMLQGGTDSLSGDRLGCFNLSIKGHGTCIEYLKKFNVPIIMVGGGGYTLRNVPRCWTYETSIALNVPIQDNIPD--ESDYKVYFGPEYKLHLPIS-NMEEQNSKDYLEKNM--------QI-------------
A0DGA6/4-361               F------KQKVTYYYDEEFGTFNYSTTHPMKPLRVAITDDLVGHYGLKQYMNCIVQDQSFVQTYIKRVDEDVLTQFHSEEYIDLIKIIT---PENKCQHEDQ--LYRFNFMEDCPVLDRLFDFCLCQTSGSVGAACVIADQKSNIAINWSGGLHHAKQSEASGFCYVNDCVLGILELLKTYQRVLYIDIDIHHGDGVEEAFYLTDRVMTCSFHKFKE-YFPGTGHIDDIGHDKGKYYAVNFPLNEGLNDDSIQLIFKPVIDSIMENFRPDVVMLQGGTDSLSGDRLGCFNLSIKGHGSCTEYLKKFNVPIIMVGGGGYTLRNVPRCWTYETSLALNVPIPDNIPD--ESDYKVYFGPEYQITFT---NL---------------------QY----GGIE-----
A0A2N5VLY4/1-387           -------MPRVAYYYDDDVGAYAYAPHHPMKPHRIKMAHNLILNAGLNKKMDMLTA---------KRATREEMTKFHTDEYICHIAQVNQEEPETLASGRDKSGDNRFLVGDDCPGFEGLFEFCSISAGGSIAAAKRINSGQADIAINWSGGLHHAKKREASGFCYVNDIVLAILELLRFHSRVLYIDIDIHHGDGVEEAFYTTDRVMTCSFHKFGD-FFPGTGHVGDRGLGKGKGYAVNVPLKTGIDDDTYRSIFRPVINHIMSWYQPGAIVLQCGADSLAEDKLGSFNLSMNGHADCVRHVKSFNVPLVVLGGGGYTIRNVARTWAFETSVCLGPHEELSLADLPYNEYMEYFGPNFKLEVPSN-NMDNHNSVDYLNGILEKVVDSLRDLPFAPSTQRRPLSF
#=GC scorecons             000000054674878855694749544999995946556597455964646644340000000004766474754996499944644760009944353546225469564799956769749534456695659349654466957999999999965699999979959569999974769999899959999999999549699996969976717999996767494669949679699659669655536949796499537695676696969995697994999975994595576959669575699999955966959479964555445454663003679459759548645545168453773575545524432242440001433313220
#=GC scorecons_70          _________**_****___*_*_*___*****_*______**___**_*_**______________**__*_*__***_***__*__**___**_______*_____*___****_**_**_*_____***_*_*__*____***_************_**********_*_*******_*_********_**********__******_*****_*_******_***_*_****_****_***_*****____**_****_**__***_*****_*****_*****_*****_**__*__***_*_**_*_*******__*_**_*_****__________**____***__**_*__**_______*___**__*____________________________
#=GC scorecons_80          __________*_*_**___*_*_*___*****_*______**___*____________________*___*____**__***_____*____**_____________*___****__*_**_*_______*___*__*______*_***********___*********_*__******_*_********_**********__*_****_*_***_*_******_*_*_*___**_*_**_**__*__*______*_***__**__*_*__*__*_*_***__****_*****_**__*__*_*_*__*_*__******__*__*_*_***___________________*__**_*__*________*___**__*____________________________
#=GC scorecons_90          ___________________*___*___*****_*______*____*_____________________________**__***__________**_____________*____***____*__*_______*___*__*______*__**********___******_**_*__*****____****_***_**********__*_****_*_**_____*****_____*___**_*__*_**__*__*______*_*_*__**____*_____*_*_***__*_**_****__**__*____*_*__*____******__*__*_*__**___________________*__*__*__*________*____________________________________
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