The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 513: ras-related protein Rab-28 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
6 P51158 (/ISS) Q3SWY9 (/ISS) Q3SWY9 (/ISS) Q5RFI2 (/ISS) Q99KL7 (/ISS) Q99KL7 (/ISS)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
6 P51158 (/ISS) Q3SWY9 (/ISS) Q3SWY9 (/ISS) Q5RFI2 (/ISS) Q99KL7 (/ISS) Q99KL7 (/ISS)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
5 P51157 (/TAS) P51157 (/TAS) P51157 (/TAS) P51157 (/TAS) P51158 (/TAS)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
5 P51157 (/IDA) P51157 (/IDA) P51157 (/IDA) P51157 (/IDA) P51158 (/IDA)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
4 P51157 (/IDA) P51157 (/IDA) P51157 (/IDA) P51157 (/IDA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 Q99KL7 (/ISO) Q99KL7 (/ISO)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
2 Q99KL7 (/ISO) Q99KL7 (/ISO)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Toxin transport GO:1901998
The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q99KL7 (/IMP) Q99KL7 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ciliary rootlet GO:0035253
A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.
9 P51157 (/ISS) P51157 (/ISS) P51157 (/ISS) P51157 (/ISS) Q3SWY9 (/ISS) Q3SWY9 (/ISS) Q5RFI2 (/ISS) Q99KL7 (/ISS) Q99KL7 (/ISS)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
9 P51157 (/ISS) P51157 (/ISS) P51157 (/ISS) P51157 (/ISS) Q3SWY9 (/ISS) Q3SWY9 (/ISS) Q5RFI2 (/ISS) Q99KL7 (/ISS) Q99KL7 (/ISS)
Ciliary rootlet GO:0035253
A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.
2 Q99KL7 (/ISO) Q99KL7 (/ISO)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
2 Q99KL7 (/ISO) Q99KL7 (/ISO)
Ciliary rootlet GO:0035253
A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.
1 P51158 (/IDA)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
1 P51158 (/IDA)
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