The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 221: Multidrug ABC transporter ATP-binding protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
19 A0A0F7RII7 (/ISS) A0A0F7RII7 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS)
(9 more)
Transmembrane transporter activity GO:0022857
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
17 Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS) Q81Y18 (/ISS)
(7 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
10 P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q9WYC3 (/IPI) Q9WYC3 (/IPI)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
6 Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q2YQ73 (/IPI) Q2YQ73 (/IPI)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
13 Q9R7V3 (/EXP) Q9R7V3 (/EXP) Q9R7V3 (/EXP) Q9Z375 (/EXP) Q9Z375 (/EXP) Q9Z375 (/EXP) Q9Z375 (/EXP) Q9Z375 (/EXP) Q9Z375 (/EXP) Q9Z375 (/EXP)
(3 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 P77265 (/IDA) P77265 (/IDA) P77265 (/IDA) P77265 (/IDA) P77265 (/IDA) P77265 (/IDA) P77265 (/IDA) P77265 (/IDA) P77265 (/IDA) P77265 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
10 P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM) P77265 (/ISM)
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