# STOCKHOLM 1.0 #=GF ID 3.40.430.10/FF/000015 #=GF DE Dihydrofolate reductase #=GF AC 3.40.430.10/FF/000015 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 37.464 #=GS P07807/4-211 AC P07807 #=GS P07807/4-211 OS Saccharomyces cerevisiae S288C #=GS P07807/4-211 DE Dihydrofolate reductase #=GS P07807/4-211 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS P07807/4-211 DR GO; GO:0003729; GO:0004146; GO:0005737; GO:0005739; GO:0005829; GO:0046452; GO:0046654; #=GS P07807/4-211 DR EC; 1.5.1.3; #=GS L0P7T1/4-214 AC L0P7T1 #=GS L0P7T1/4-214 OS Pneumocystis jirovecii SE8 #=GS L0P7T1/4-214 DE Uncharacterized protein #=GS L0P7T1/4-214 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Pneumocystidomycetes; Pneumocystidales; Pneumocystidaceae; Pneumocystis; Pneumocystis jirovecii; #=GS Q75BZ5/3-210 AC Q75BZ5 #=GS Q75BZ5/3-210 OS Eremothecium gossypii ATCC 10895 #=GS Q75BZ5/3-210 DE ACR124Wp #=GS Q75BZ5/3-210 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium; Eremothecium gossypii; #=GS A0A0L8VH25/4-211 AC A0A0L8VH25 #=GS A0A0L8VH25/4-211 OS Saccharomyces sp. 'boulardii' #=GS A0A0L8VH25/4-211 DE DFR1p Dihydrofolate reductase involved in tetrahydrofolate biosynthesis #=GS A0A0L8VH25/4-211 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; #=GS C8ZGZ0/4-211 AC C8ZGZ0 #=GS C8ZGZ0/4-211 OS Saccharomyces cerevisiae EC1118 #=GS C8ZGZ0/4-211 DE Dfr1p #=GS C8ZGZ0/4-211 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS C8ZGZ0/4-211 DR EC; 1.5.1.3; #=GS B3LJQ7/4-211 AC B3LJQ7 #=GS B3LJQ7/4-211 OS Saccharomyces cerevisiae RM11-1a #=GS B3LJQ7/4-211 DE Dihydrofolate reductase #=GS B3LJQ7/4-211 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS B3LJQ7/4-211 DR EC; 1.5.1.3; #=GS N1P3I2/4-211 AC N1P3I2 #=GS N1P3I2/4-211 OS Saccharomyces cerevisiae CEN.PK113-7D #=GS N1P3I2/4-211 DE Dfr1p #=GS N1P3I2/4-211 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS N1P3I2/4-211 DR EC; 1.5.1.3; #=GS A6ZP76/4-211 AC A6ZP76 #=GS A6ZP76/4-211 OS Saccharomyces cerevisiae YJM789 #=GS A6ZP76/4-211 DE Dihydrofolate reductase #=GS A6ZP76/4-211 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS C7GWF0/4-211 AC C7GWF0 #=GS C7GWF0/4-211 OS Saccharomyces cerevisiae JAY291 #=GS C7GWF0/4-211 DE Dfr1p #=GS C7GWF0/4-211 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GS G2WNA5/4-211 AC G2WNA5 #=GS G2WNA5/4-211 OS Saccharomyces cerevisiae Kyokai no. 7 #=GS G2WNA5/4-211 DE K7_Dfr1p #=GS G2WNA5/4-211 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; #=GF SQ 10 P07807/4-211 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESNFKE-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYC--FEFTLYNR--K L0P7T1/4-214 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESNFKK-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYSAGFEFTLYNLI-E Q75BZ5/3-210 ISRVPVVSIVACLLPEYGIGYQGQLPWRLAREMKYFRQATTATFDPTKRNAVVMGRKTWESIPARWRPLPGRLNVVVSRTYTSPWAHDENGHVITSNSLQQCVRQLQEQARALGVERIYIMGGAEIYNQSYDLCDHLLVTELQVAPDGPAVLLDTFLARDVLEQSFA-KNSAGPRALLPPSVELPECPA---TALEEGGFQ--FRFALYDHLNR A0A0L8VH25/4-211 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKGDFVHDKERSIVQSNSLANAITNLESNFKE-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYC--FEFTLYNR--K C8ZGZ0/4-211 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESNFKE-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYC--FEFTLYNR--K B3LJQ7/4-211 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESNFKE-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYC--FEFTLYNR--K N1P3I2/4-211 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESNFKE-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYC--FEFTLYNR--K A6ZP76/4-211 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKGDFVHDKERSIVQSNSLANAITNLESNFKE-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYC--FEFTLYNR--K C7GWF0/4-211 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAITNLESNFKE-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYC--FEFTLYNR--K G2WNA5/4-211 -GKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAITNLESNFKE-HLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYC--FEFTLYNR--K #=GC scorecons 0566969599999499399975949999954999999959549399596995699999999995649999596996699574444599555466499994546359545364045999966995969594755499496955544455554469999445399549535559456459994999994443333599949730095959954005 #=GC scorecons_70 __*****_*****_**_****_*_*****__*******_*__*_**_****_***********_*_****_*_******_*_____**____**_****___*__*____*____*****_**_***_*_*___**_***_____________****____**__*_____*__*__***_*****________***_**___*_*_**_____ #=GC scorecons_80 ____*_*_*****_**_***__*_*****__*******_*__*_**_*_**__**********___****_*_**__**_______**_______****______*_________****__**_*_*_*_____**_*_*_____________****____**__*_____*_____***_*****________***_*____*_*_**_____ #=GC scorecons_90 ____*_*_*****_**_***__*_*****__*******_*__*_**_*_**__**********___****_*_**__**_______**_______****______*_________****__**_*_*_*_____**_*_*_____________****____**__*_____*_____***_*****________***_*____*_*_**_____ //