# STOCKHOLM 1.0
#=GF ID 3.40.430.10/FF/000013
#=GF DE Dihydrofolate reductase
#=GF AC 3.40.430.10/FF/000013
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 76.204
#=GS U9W889/7-241      AC U9W889
#=GS U9W889/7-241      OS Neurospora crassa OR74A
#=GS U9W889/7-241      DE Dihydrofolate reductase
#=GS U9W889/7-241      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; Neurospora; Neurospora crassa; 
#=GS Q0U312/2-208      AC Q0U312
#=GS Q0U312/2-208      OS Parastagonospora nodorum SN15
#=GS Q0U312/2-208      DE Uncharacterized protein
#=GS Q0U312/2-208      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae; Parastagonospora; Parastagonospora nodorum; 
#=GS A0A1D9QJT4/3-212  AC A0A1D9QJT4
#=GS A0A1D9QJT4/3-212  OS Sclerotinia sclerotiorum 1980 UF-70
#=GS A0A1D9QJT4/3-212  DE Uncharacterized protein
#=GS A0A1D9QJT4/3-212  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes; Helotiales; Sclerotiniaceae; Sclerotinia; Sclerotinia sclerotiorum; 
#=GS A0A0S7DWF3/2-254  AC A0A0S7DWF3
#=GS A0A0S7DWF3/2-254  OS Aspergillus lentulus
#=GS A0A0S7DWF3/2-254  DE Dihydrofolate reductase
#=GS A0A0S7DWF3/2-254  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus lentulus; 
#=GS Q4X1T0/1-249      AC Q4X1T0
#=GS Q4X1T0/1-249      OS Aspergillus fumigatus Af293
#=GS Q4X1T0/1-249      DE Dihydrofolate reductase, putative
#=GS Q4X1T0/1-249      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fumigatus; 
#=GS A1DGI8/1-246      AC A1DGI8
#=GS A1DGI8/1-246      OS Aspergillus fischeri NRRL 181
#=GS A1DGI8/1-246      DE Dihydrofolate reductase, putative
#=GS A1DGI8/1-246      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fischeri; 
#=GS A0A0K8LGS7/1-249  AC A0A0K8LGS7
#=GS A0A0K8LGS7/1-249  OS Aspergillus udagawae
#=GS A0A0K8LGS7/1-249  DE Dihydrofolate reductase
#=GS A0A0K8LGS7/1-249  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus udagawae; 
#=GS A0A2I1CM66/1-247  AC A0A2I1CM66
#=GS A0A2I1CM66/1-247  OS Aspergillus novofumigatus IBT 16806
#=GS A0A2I1CM66/1-247  DE Putative dihydrofolate reductase
#=GS A0A2I1CM66/1-247  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus novofumigatus; 
#=GS A0A0B0DNU9/7-241  AC A0A0B0DNU9
#=GS A0A0B0DNU9/7-241  OS Neurospora crassa
#=GS A0A0B0DNU9/7-241  DE Uncharacterized protein
#=GS A0A0B0DNU9/7-241  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; Neurospora; Neurospora crassa; 
#=GS A7ETZ6/3-212      AC A7ETZ6
#=GS A7ETZ6/3-212      OS Sclerotinia sclerotiorum 1980 UF-70
#=GS A7ETZ6/3-212      DE Uncharacterized protein
#=GS A7ETZ6/3-212      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes; Helotiales; Sclerotiniaceae; Sclerotinia; Sclerotinia sclerotiorum; 
#=GS B0XRT8/1-249      AC B0XRT8
#=GS B0XRT8/1-249      OS Aspergillus fumigatus A1163
#=GS B0XRT8/1-249      DE Dihydrofolate reductase, putative
#=GS B0XRT8/1-249      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fumigatus; 
#=GS A0A0J5SWB3/1-249  AC A0A0J5SWB3
#=GS A0A0J5SWB3/1-249  OS Aspergillus fumigatus Z5
#=GS A0A0J5SWB3/1-249  DE Dihydrofolate reductase
#=GS A0A0J5SWB3/1-249  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fumigatus; 
#=GS A0A229YCJ6/1-249  AC A0A229YCJ6
#=GS A0A229YCJ6/1-249  OS Aspergillus fumigatus
#=GS A0A229YCJ6/1-249  DE Uncharacterized protein
#=GS A0A229YCJ6/1-249  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fumigatus; 
#=GF SQ 13
U9W889/7-241              ----SIELTLVLAATR---------DMGIGLNGGLPWTGLKKEMAYFARVTKRLPS-QLAGTKALNAVIMGRKTWESIPPKFRPLKGRLNIVISRSVTSS------PSL-------------SSPSSSS----SSSSEVEEGPVM--ASSLEQAIEYLHHCQQQQQQQQQQQQQEQQQKVGKVFVIGGGQIYGAALKLPKEVSKRILLTRVLS---PEFECDTFFPLELKEEGEASGSEEWVRKSKEELDQFVGE-EVPEGLQVENGTEYEFQMWERR
Q0U312/2-208              -P-KSPSLTLILAATP---------SLGIGKGGTLPWPQLKKEMGYFARVTKRVSSPQSTGTRKVNAVLMGRKTWDSIPPKFRPLKDRLNIVITRKA-------------------------DEFEKTL----DKKSDVE-GPMV--ASGIVDALAQL---------------EGKAEEVDRVYVIGGASVYQTALELPQ--TRYVLLTKIRK----EFECDTFFSVDLEESAV------WRRAGREELQEFTGE-EVKEKVIEEHGVEFEFCLYERV
A0A1D9QJT4/3-212          ---PIKEFTLIVAATN---------KMGVGKGGGLPWTGLRKEMAYFARVTKR------AGPGKTNAVVMGRKTWESIPPKFRPLANRANYMISRTQT-----------------------------------SNSPEVDLGPDAHSATSLTDALEKL------GSRAQSNTNHEDEKEIDRVFIIGGGQIYKASLELKE--AKRILLTRILE----DFECDTYFPVELKEDGTGKG---WRRTDTQALREWTGEGEEVENIKEEAGVKYIFEMWEKV
A0A0S7DWF3/2-254          PPTPSQPLTLIVATTPIRTSENLPTRLGIGLHGTLPWPRIKADMAFFARATSRAPR-----PGTINAIVMGRKTYDSLPSHLRPLAKRINVVITRDATGSVRERIMRELEVKRAKAAAVAA-EQAQAQAQKHDQKQEQAQAQTDALVSTGLEDALASL------------ESGYGAEGRLGNVFVIGGAEIYASALRMSETQPVRIVMTNVERVDGTEFECDTFFPVD-EELSAGGK---WRMASEEEVSGWVGE-EVSSKWREEGDVRIQMVGYE--
Q4X1T0/1-249              MP-PSQPLTLIVATTPIRTSENLPTRLGIGLHGTLPWPRIKADMAFFARATSRPPR-----PGTTNAIIMGRKTYDSLPQNLRPLAKRINVVITRDSTGSVRERIMKELEAKRAKAAAAAASEQAQAQA----QKQEQVQAQTDALVSTGLEDALASL------------EGSYGAEGRLGNVFVIGGGEIYASALRMSETQPLRIVMTNVERVDGTEFECDTVFPVD-EKLAAGGK---WRMASEEEVSGWVGE-EVSSRWREEGDVRIQMVGYE--
A1DGI8/1-246              MP-PSQPLTLIVATTPIRTSENLPTRLGIGLHGTLPWPRIKADMAFFARATSRPPR-----PGTTNAIIMGRKTYDSLPQNLRPLAKRINVVITRDSTGSVRERIMRELEAKRAKAAAA---EQAQAQA----QKQEQAQAQTDALVSTGLEDALASL------------EGGYGAEGRLGNVFVIGGAEIYASALRMSETQPLRIVMTNVERVDGTEFECDTFFPVD-KELAAGGK---WRMASEEEVSGWVGE-EVSSKWREEGDVRIQMVGYE--
A0A0K8LGS7/1-249          MP-PSQPLTLIVATTPIRTSENLPTRLGIGLHGTLPWPRIKADMAFFARVTSRPPR-----PGTTNAIVMGRKTYDSLPQNLRPLAKRINVVITRDTTGSVRERIMRELEAKRAKAAAAAAAAEQQAQA----QKQEQAEARTDALVSTGLEDALASL------------ESGYEAEGRLGNVFVIGGAELYAAALRISETKPVRIVMTNVERVDGTEFECDTFFPVD-EELAAGGK---WRMASEEEVSGWVGE-QVSSKWREEGDVRIQMMGYE--
A0A2I1CM66/1-247          MP-PSQPLTLIVATTPIRTSENLPTRLGIGLHGTLPWPRIKADMAFFARATSRPPR-----PGTTNAIVMGRKTYDSLPQHLRPLAKRINVVITRDATGSVRERIMRELEAKRAKAVAVAAAEQAQAQA----QKQE--QAQTDALVSTGLEDALASL------------EGGYGAEGKLGNVFVIGGAEIYASVLRMSETQPVRIVMTNVERVDGTEFECDTFFPVD-EELSTGEK---WRMASEEEVSGWVGE-QVSSKWREEGDVRIQMVGYE--
A0A0B0DNU9/7-241          ----SIELTLVLAATR---------DMGIGLNGGLPWTGLKKEMAYFARVTKRLPS-QLAGTKALNAVIMGRKTWESIPPKFRPLKGRLNIVISRSVTSS------PSL-------------SSPSSSS----SSSSEVEEGPVM--ASSLEQAIEYLHHCQQQQQQQQQQQQQEQQQKVGKVFVIGGGQIYGAALKLPKEVSKRILLTRVLS---PEFECDTFFPLELKEEGEASGSEEWVRKSKEELDQFVGE-EVPEGLQVENGTEYEFQMWERR
A7ETZ6/3-212              ---PIKEFTLIVAATN---------KMGVGKGGGLPWTGLRKEMAYFARVTKR------AGPGKTNAVVMGRKTWESIPPKFRPLANRANYMISRTQT-----------------------------------SNSPEVDLGPDAHSATSLTDALEKL------GSRAQSNTNHEDEKEIDRVFIIGGGQIYKASLELKE--AKRILLTRILE----DFECDTYFPVELKEDGTGKG---WRRTDTQALREWTGEGEEVENIKEEAGVKYIFEMWEKV
B0XRT8/1-249              MP-PSQPLTLIVATTPIRTSENLPTRLGIGLHGTLPWPRIKADMAFFARATSRPPR-----PGTTNAIIMGRKTYDSLPQNLRPLAKRINVVITRDSTGSVRERIMKELEAKRAKAAAAAASEQAQAQA----QKQEQVQAQTDALVSTGLEDALASL------------EGSYGAEGRLGNVFVIGGGEIYASALRMSETQPLRIVMTNVERVDGTEFECDTVFPVD-EKLAAGGK---WRMASEEEVSGWVGE-EVSSRWREEGDVRIQMVGYE--
A0A0J5SWB3/1-249          MP-PSQPLTLIVATTPIRTSENLPTRLGIGLHGTLPWPRIKADMAFFARATSRPPR-----PGTTNAIIMGRKTYDSLPQNLRPLAKRINVVITRDSTGSVRERIMKELEAKRAKAAAAAASEQAQAQA----QKQEQVQAQTDALVSTGLEDALASL------------EGSYGAEGRLGNVFVIGGGEIYASALRMSETQPLRIVMTNVERVDGTEFECDTVFPVD-EKLAAGGK---WRMASEEEVSGWVGE-EVSSRWREEGDVRIQMVGYE--
A0A229YCJ6/1-249          MP-PSQPLTLIVATTPIRTSENLPTRLGIGLHGTLPWPRIKADMAFFARATSRPPR-----PGTTNAIIMGRKTYDSLPQNLRPLAKRINVVITRDSTGSVRERIMKELEAKRAKAAAAAASEQAQAQA----QKQEQVQAQTDALVSTGLEDALASL------------EGSYGAEGRLGNVFVIGGGEIYASALRMSETQPLRIVMTNVERVDGTEFECDTVFPVD-EKLAAGGK---WRMASEEEVSGWVGE-EVSSRWREEGDVRIQMVGYE--
#=GC scorecons            12046447997696941111111114697954959996567579779996959243000126545997699999579695569995495957969437231111112231111111111110222333300004544565356552266675697549000000000010433464645565987999657945695646225378669573411127999995977726635453400096555476645569907645435694665445345911
#=GC scorecons_70         ____*__********___________****__*_***__**_*******_*_*________*___*********_****__****__*_*_**_*__*__________________________________________________*_*_***__*______________________*_*******_**__**_*______*****_*______******_****__*_________*_____***____**_**_____**__*_______*__
#=GC scorecons_80         _______****_*_*____________***__*_***___*__******_*_*____________**__*****__*_*___***__*_*_**_*_______________________________________________________*__**__*________________________******__**___*________**__*_*______******_***_____________*_____*______**_*_______*__________*__
#=GC scorecons_90         ________**__*_*____________*_*__*_***______*__***_*_*____________**__*****__*_*___***__*_*__*_*__________________________________________________________*___*________________________**_***___*___*_________*__*_________*****_*_______________*____________**_________*__________*__
//