# STOCKHOLM 1.0
#=GF ID 3.40.1190.10/FF/000015
#=GF DE Dihydrofolate synthase/folylpolyglutamate synthase
#=GF AC 3.40.1190.10/FF/000015
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 65.234
#=GS Q8IE69/45-322      AC Q8IE69
#=GS Q8IE69/45-322      OS Plasmodium falciparum 3D7
#=GS Q8IE69/45-322      DE Dihydrofolate synthase/folylpolyglutamate synthase
#=GS Q8IE69/45-322      DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS Q8IE69/45-322      DR GO; GO:0005524; GO:0008841; 
#=GS H3GXU6/76-361      AC H3GXU6
#=GS H3GXU6/76-361      OS Phytophthora ramorum
#=GS H3GXU6/76-361      DE Uncharacterized protein
#=GS H3GXU6/76-361      DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora ramorum; 
#=GS B8CBL4/4-269       AC B8CBL4
#=GS B8CBL4/4-269       OS Thalassiosira pseudonana
#=GS B8CBL4/4-269       DE Folylpolyglutamate synthase
#=GS B8CBL4/4-269       DR ORG; Eukaryota; Bacillariophyta; Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales; Thalassiosiraceae; Thalassiosira; Thalassiosira pseudonana; 
#=GS A0A060RXM6/45-323  AC A0A060RXM6
#=GS A0A060RXM6/45-323  OS Plasmodium reichenowi
#=GS A0A060RXM6/45-323  DE Dihydrofolate synthase/folylpolyglutamate synthase
#=GS A0A060RXM6/45-323  DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium reichenowi; 
#=GS W7JPW2/45-322      AC W7JPW2
#=GS W7JPW2/45-322      OS Plasmodium falciparum NF54
#=GS W7JPW2/45-322      DE Dihydrofolate synthase/folylpolyglutamate synthase
#=GS W7JPW2/45-322      DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS A0A024X4C6/45-322  AC A0A024X4C6
#=GS A0A024X4C6/45-322  OS Plasmodium falciparum CAMP/Malaysia
#=GS A0A024X4C6/45-322  DE Uncharacterized protein
#=GS A0A024X4C6/45-322  DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS Q9U738/45-322      AC Q9U738
#=GS Q9U738/45-322      OS Plasmodium falciparum
#=GS Q9U738/45-322      DE Dihydrofolate synthase/folylpolyglutamate synthase
#=GS Q9U738/45-322      DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS W4IZ23/45-322      AC W4IZ23
#=GS W4IZ23/45-322      OS Plasmodium falciparum Palo Alto/Uganda
#=GS W4IZ23/45-322      DE Uncharacterized protein
#=GS W4IZ23/45-322      DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS W4IBG9/45-322      AC W4IBG9
#=GS W4IBG9/45-322      OS Plasmodium falciparum NF135/5.C10
#=GS W4IBG9/45-322      DE Uncharacterized protein
#=GS W4IBG9/45-322      DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS A0A024V1W6/45-322  AC A0A024V1W6
#=GS A0A024V1W6/45-322  OS Plasmodium falciparum Vietnam Oak-Knoll (FVO)
#=GS A0A024V1W6/45-322  DE Uncharacterized protein
#=GS A0A024V1W6/45-322  DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS W7F302/45-322      AC W7F302
#=GS W7F302/45-322      OS Plasmodium falciparum 7G8
#=GS W7F302/45-322      DE Uncharacterized protein
#=GS W7F302/45-322      DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS W7FDW1/45-322      AC W7FDW1
#=GS W7FDW1/45-322      OS Plasmodium falciparum Santa Lucia
#=GS W7FDW1/45-322      DE Uncharacterized protein
#=GS W7FDW1/45-322      DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS A0A0L7K8L7/29-306  AC A0A0L7K8L7
#=GS A0A0L7K8L7/29-306  OS Plasmodium falciparum HB3
#=GS A0A0L7K8L7/29-306  DE Uncharacterized protein
#=GS A0A0L7K8L7/29-306  DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS A0A0L1IDH9/45-322  AC A0A0L1IDH9
#=GS A0A0L1IDH9/45-322  OS Plasmodium falciparum IGH-CR14
#=GS A0A0L1IDH9/45-322  DE Dihydrofolate synthase/folylpolyglutamate synthase
#=GS A0A0L1IDH9/45-322  DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS A0A024VG63/45-319  AC A0A024VG63
#=GS A0A024VG63/45-319  OS Plasmodium falciparum FCH/4
#=GS A0A024VG63/45-319  DE Uncharacterized protein
#=GS A0A024VG63/45-319  DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS A0A024WKJ9/45-325  AC A0A024WKJ9
#=GS A0A024WKJ9/45-325  OS Plasmodium falciparum MaliPS096_E11
#=GS A0A024WKJ9/45-325  DE Uncharacterized protein
#=GS A0A024WKJ9/45-325  DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GS W7JIV1/45-322      AC W7JIV1
#=GS W7JIV1/45-322      OS Plasmodium falciparum UGT5.1
#=GS W7JIV1/45-322      DE Uncharacterized protein
#=GS W7JIV1/45-322      DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; 
#=GF SQ 17
Q8IE69/45-322              LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
H3GXU6/76-361              D--AKHEMKAAATAAHYAELLQRLYQVNRFSAVKLGLENMQKLNAAFGDPASQ--FEIVHVAGTNGKGSVAFKVAKALERSGYKTGLFVSPHVACFRERVQVNNRLITESEVCEALSEIFNISAQLRIPATFFEITTMLAFMHFAKQGVDCVVLETGLGGRLDSTNIVT-PALSVITSIGMDHMRILGNTRDAIAREKAGIIKPNVPVVVGPNTPV--NVMMEFAARNNAPLVRV--------PLHADFEEDYNAENAAIAREACVQLNALH--ALQTGDV-RVPKQLCVDLTSERVNAALESR
B8CBL4/4-269               L----------------------------FNPVKLGLENMDQLHKALGSPMDKSDISIIHIAGSNGKGSVALKTANALQLAGYKVGLFVSPHISSFRERIQINGQPISESQVEKYLQEIFDICEGEEIPATFFEVTTALAFHIFGQEKVDVVVLETGLGGRLDATNVISKPALSIITSIGLEHTRILGDTIELIAGEKAGIIKKDCPVLIGKNAPF--DVLERCAREKGASEVYQSDDLLGPDPKEGEEVGDYDAENSRIASAGLILLQFHM--AQQSIDAGKQPKIMTPAEIEEGVK------
A0A060RXM6/45-323          LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKYKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLATE----------
W7JPW2/45-322              LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
A0A024X4C6/45-322          LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
Q9U738/45-322              LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
W4IZ23/45-322              LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
W4IBG9/45-322              LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
A0A024V1W6/45-322          LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
W7F302/45-322              LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
W7FDW1/45-322              LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
A0A0L7K8L7/29-306          LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
A0A0L1IDH9/45-322          LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
A0A024VG63/45-319          LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQY--------------
A0A024WKJ9/45-325          LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLATEQI--------
W7JIV1/45-322              LHKINNEEKKYEEIKSYSECLELLY---KTHALKLGLDNPKKLNESFGHPCDK--YKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAFLHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGIFKKDANVVIGPSVAIYKNVFDK------AKELNCTIHTVVPEPR----GERYNEENSRIALRTLEILNISIDYFLKSIIPIKPPLRIQYLAT-----------
#=GC scorecons             5223335253233333535253255000344669999694469645694946600545797996999999559544595445796999599973669997479556969566344649666444453955599975946994593456994566999699999699756595657999994794599965444954995995956459679554552269545010000945643323332549400004659659966993455449643422456654427494453333501010000000
#=GC scorecons_70          _______________________________*_******__***__**_*_**_____************__*____*____******_****_*_****_**__****_*______**_*______*___****_*__**__*____**__*_***_*********_*_*___******_**__****____*__**_**_*_*__****_______**_________*_____________*______*_**_***_**______**________*____*_*___________________
#=GC scorecons_80          _________________________________****_*___*____*_*________*****_******__*____*____**_***_****___****_**___*_*________*_________*___****_*__**__*____**____***_*****_***___*___******_**__***_____*__**_**_*____*_**________*_________*_____________*________*__**__**______*______________*_*___________________
#=GC scorecons_90          _________________________________****_*___*____*_*_________*_**_******__*____*_____*_***_***____***___*___*_*________*_________*___***__*__**__*____**____***_*****_**____*____*****__*__***_____*__**_**_*____*__*________*_________*_____________*________*__**__**______*________________*___________________
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