# STOCKHOLM 1.0 #=GF ID 3.30.505.10/FF/000094 #=GF DE Cytokine-inducible SH2-containing protein #=GF AC 3.30.505.10/FF/000094 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 90.165 #=GS Q7JVF1/173-338 AC Q7JVF1 #=GS Q7JVF1/173-338 OS Drosophila melanogaster #=GS Q7JVF1/173-338 DE LP02169p #=GS Q7JVF1/173-338 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q7JVF1/173-338 DR GO; GO:0045742; GO:0046426; #=GS E9QCT0/30-167 AC E9QCT0 #=GS E9QCT0/30-167 OS Danio rerio #=GS E9QCT0/30-167 DE Cytokine-inducible SH2-containing protein #=GS E9QCT0/30-167 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GS E9QCT0/30-167 DR GO; GO:0045620; GO:0045638; GO:0045647; GO:0046426; GO:1903707; #=GS C3XWJ1/10-181 AC C3XWJ1 #=GS C3XWJ1/10-181 OS Branchiostoma floridae #=GS C3XWJ1/10-181 DE Uncharacterized protein #=GS C3XWJ1/10-181 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GS B7ZTW0/77-257 AC B7ZTW0 #=GS B7ZTW0/77-257 OS Xenopus tropicalis #=GS B7ZTW0/77-257 DE Cish protein #=GS B7ZTW0/77-257 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GS A0A1L8GPF7/86-266 AC A0A1L8GPF7 #=GS A0A1L8GPF7/86-266 OS Xenopus laevis #=GS A0A1L8GPF7/86-266 DE Uncharacterized protein #=GS A0A1L8GPF7/86-266 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis; #=GS B4KNW8/220-384 AC B4KNW8 #=GS B4KNW8/220-384 OS Drosophila mojavensis #=GS B4KNW8/220-384 DE Uncharacterized protein #=GS B4KNW8/220-384 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; repleta group; mulleri subgroup; Drosophila mojavensis; #=GS A0A0M3QVI7/191-356 AC A0A0M3QVI7 #=GS A0A0M3QVI7/191-356 OS Drosophila busckii #=GS A0A0M3QVI7/191-356 DE Socs44A #=GS A0A0M3QVI7/191-356 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Dorsilopha; Drosophila busckii; #=GS A0A1L8GHD3/84-264 AC A0A1L8GHD3 #=GS A0A1L8GHD3/84-264 OS Xenopus laevis #=GS A0A1L8GHD3/84-264 DE Uncharacterized protein #=GS A0A1L8GHD3/84-264 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis; #=GS F7C1F6/77-225 AC F7C1F6 #=GS F7C1F6/77-225 OS Xenopus tropicalis #=GS F7C1F6/77-225 DE Cytokine-inducible SH2-containing protein #=GS F7C1F6/77-225 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GS B4QFA9/171-336 AC B4QFA9 #=GS B4QFA9/171-336 OS Drosophila simulans #=GS B4QFA9/171-336 DE GD10544 #=GS B4QFA9/171-336 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B4NMQ9/184-348 AC B4NMQ9 #=GS B4NMQ9/184-348 OS Drosophila willistoni #=GS B4NMQ9/184-348 DE Uncharacterized protein #=GS B4NMQ9/184-348 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; #=GS B4LJM5/214-378 AC B4LJM5 #=GS B4LJM5/214-378 OS Drosophila virilis #=GS B4LJM5/214-378 DE Uncharacterized protein #=GS B4LJM5/214-378 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GS B4HRJ9/171-336 AC B4HRJ9 #=GS B4HRJ9/171-336 OS Drosophila sechellia #=GS B4HRJ9/171-336 DE GM21010 #=GS B4HRJ9/171-336 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS A0A1W4WAQ4/168-333 AC A0A1W4WAQ4 #=GS A0A1W4WAQ4/168-333 OS Drosophila ficusphila #=GS A0A1W4WAQ4/168-333 DE uncharacterized protein LOC108101491 #=GS A0A1W4WAQ4/168-333 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS B3N982/171-336 AC B3N982 #=GS B3N982/171-336 OS Drosophila erecta #=GS B3N982/171-336 DE Uncharacterized protein #=GS B3N982/171-336 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GF SQ 15 Q7JVF1/173-338 P-NQIMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRD-NFWHFEE---------LKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQP---PFP----------VI-LKYPLSRYSNMPKLQDLCRRVLQRQ-MSREQLAQLPVPAQMLEYLSVE--REL E9QCT0/30-167 KDYRALTLNFSYLDASGWYWGGISASEAHSVLKGASEGTFLIRDSSHPDYMLTLSVKTVRGPTNVRIEYRQ-CRFSLDSSSPARS-HLQSFPDVHSLVQHYVG-SKSE----KNEEKMEEAH---HVISSAPKECSVLLK-LKKPIH-----------CP---------------------------------- C3XWJ1/10-181 SDIHILTGTLNMLEASGWYWASVSRYEAAALLSGKEEGTFLVRDSADPGHLFSLSLQTARGVLSARIVYTEHGTFRLDS--IGKPCDSPHFDCVVKLLDFYMKESSGG----TTKHR-WVEPCGSPFP----------LK-VSRPLR--CKVCDLKHLCRRTIHAH-TQKGQVDELYLPEALKTYLKAYPYRH- B7ZTW0/77-257 --LLCIARTFCYLRESGWYWGSITATEAKQQLQKMPEGFFLVRDSTHPSYLFTLSVRTNRGPTNVRIEYSD-GLFRLDSNCLSKP-RILSFPDVVSLVQYYVSFCHSD----VNKEPACQTP---PVPPSPKEPAAVHLK-LLHPLPRGAQCPSLQHLCRLQINRSLAPNAELTELPLPRRMVEYLQRYPFRL- A0A1L8GPF7/86-266 --LLCIAKTFCYLRESGWYWGSITATEAKQQLQKMPEGYFLVRDSTHPSYLFTLSVRTNRGPTNVRIEYSD-GLFRLDSNCLSKP-RILSFPDVVSLVQYYLSFCHSD----VNKEPPCQST---PVPPSPKEPAAVHLK-LLHPLPRGAQCPSLQHLCRLQINQSLAPNADLMELPLPKRMVEYLQRYPFRL- B4KNW8/220-384 --NEVMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSESTGSHFTLSFRILNVTLHYRLEYRD-QFWHFEE---------LKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQP---PFP----------VI-LKYPLSRYLNMPKLQDLCRRVLQRQ-MPVSELARLPVPAQMLEYLSVE--REL A0A0M3QVI7/191-356 P-NEVMYKACSEMLEQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRILNVTLHYRLEYRD-EFWHFEE---------LKYESIVEMIEDILRRCTNDNFVCFVKVPNEMQP---PFP----------VI-LKYPLSRYLNMPKLQDLCRRVLQSQ-MPVTKLMQLPVPAQMLEYLCVK--REL A0A1L8GHD3/84-264 --LLCIARTFCYLRESGWYWGSITATEAKQQLQKMPEGFFLVRDSTHPSYLFTLSVRTNRGPTNVRIEYSD-GLFRLDSNCLSKP-RILSFPDVVSLVQYYLSFCHSD----VNKETPCQST---PVPPSPKEPAAVHLK-LLHPLPRGAQCPSLQHLCRLQINRSLAPNAELMELPLPKRMVEYLQRYPFKL- F7C1F6/77-225 --LLCIARTFCYLRESGWYWGSITATEAKQQLQKMPEGFFLVRDSTHPSYLFTLSVRTNRGPTNVRIEYSD-GLFRLDSNCLSKP-RILSFPDVVSLVQYYVSFCHSD----VNKEPACQTP---PVPPSPKEPAAVHLKCTLCPVVHSAPVYNICADCR---------------------------------- B4QFA9/171-336 P-NQIMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRD-NFWHFEE---------LKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQP---PFP----------VI-LKYPLSRYANMPKLQDLCRRVLQRQ-MSREQLAQLPVPAQMLEYLSVE--REL B4NMQ9/184-348 --NEVMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEFRD-DFWHFEE---------LKYESIVKMIDDILHRCTNDNFVCFVKVPNEIQP---PFP----------VI-LKYPLSRYLNMPKLQDLCRRVLQRQ-MPMDELAQLPVPAKMLEYLSVE--REL B4LJM5/214-378 --NEVMYKACLEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRD-EFWHFEE---------LKYESIVDMIKDILHRCTNDNFVCFVKVPNEMQP---PFP----------VI-LKYPLSRYLNMPKLQDLCRRVLQSQ-MTVAELAQLPVPAQMLEYLSVE--REL B4HRJ9/171-336 P-NQIMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRD-NFWHFEE---------LKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQP---PFP----------VI-LKYPLSRYANMPKLQDLCRRVLQRQ-MSREQLAQMPVPAQMLEYLSVE--REL A0A1W4WAQ4/168-333 P-NQVMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEFRD-DFWHFEE---------LKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQP---PFP----------VI-LKYPLSRYANMPKLQDLCRRVLQRQ-MSREQLAQLPVPAQMLEYLSVE--REL B3N982/171-336 P-NQIMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEFRD-EFWHFEE---------LKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQP---PFP----------VI-LKYPLSRYANMPKLQDLCRRVLQRQ-MPREQLAQLPVPAQMLEYLSVE--REL #=GC scorecons 10334645555363455999758654765469544659499899944555477995764555554967857044556751111210116474577466545643745711114474534346000757111010111064064497442333436535973233330332234235435234345522200521 #=GC scorecons_70 ____________*____****_**__*____*___*_*_******______****_*________****_*_____**__________*_*__**_**___*__*__*______*______*___*_*__________*__*__**____________**__________________________________ #=GC scorecons_80 _________________****_*________*_____*_******______****_*________*_**_____________________*___*____________*______*__________*_*________________*_____________**__________________________________ #=GC scorecons_90 _________________***__*________*_____*_******________**__________*__*___________________________________________________________________________*_____________*___________________________________ //