# STOCKHOLM 1.0 #=GF ID 3.30.505.10/FF/000080 #=GF DE Pi3K21B, isoform C #=GF AC 3.30.505.10/FF/000080 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 94.775 #=GS Q7KTZ2/316-422 AC Q7KTZ2 #=GS Q7KTZ2/316-422 OS Drosophila melanogaster #=GS Q7KTZ2/316-422 DE Pi3K21B, isoform B #=GS Q7KTZ2/316-422 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q7KTZ2/316-422 DR GO; GO:0001784; GO:0005943; GO:0008286; GO:0008361; GO:0019900; GO:0035014; GO:0042127; GO:0046854; #=GS O18683/326-432 AC O18683 #=GS O18683/326-432 OS Drosophila melanogaster #=GS O18683/326-432 DE LD42724p #=GS O18683/326-432 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS O18683/326-432 DR GO; GO:0005829; GO:0005943; GO:0008361; GO:0019900; GO:0035014; GO:0042127; GO:0043560; GO:0046854; #=GS M9PAY7/17-123 AC M9PAY7 #=GS M9PAY7/17-123 OS Drosophila melanogaster #=GS M9PAY7/17-123 DE Pi3K21B, isoform C #=GS M9PAY7/17-123 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS M9PAY7/17-123 DR GO; GO:0008286; GO:0008361; GO:0019900; GO:0035014; GO:0042127; GO:0046854; #=GS T1EIM1/2-108 AC T1EIM1 #=GS T1EIM1/2-108 OS Helobdella robusta #=GS T1EIM1/2-108 DE Uncharacterized protein #=GS T1EIM1/2-108 DR ORG; Eukaryota; Metazoa; Annelida; Clitellata; Hirudinea; Hirudinida; Glossiphoniiformes; Glossiphoniidae; Helobdella; Helobdella robusta; #=GS A7UTR8/474-591 AC A7UTR8 #=GS A7UTR8/474-591 OS Anopheles gambiae #=GS A7UTR8/474-591 DE AGAP005583-PA #=GS A7UTR8/474-591 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS E9HA70/275-390 AC E9HA70 #=GS E9HA70/275-390 OS Daphnia pulex #=GS E9HA70/275-390 DE Putative phosphatidylinositol 3-kinase #=GS E9HA70/275-390 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS E9G0D1/307-421 AC E9G0D1 #=GS E9G0D1/307-421 OS Daphnia pulex #=GS E9G0D1/307-421 DE Putative phosphatidylinositol 3-kinase #=GS E9G0D1/307-421 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS A0A0R4IYS3/7-134 AC A0A0R4IYS3 #=GS A0A0R4IYS3/7-134 OS Danio rerio #=GS A0A0R4IYS3/7-134 DE Phosphoinositide-3-kinase, regulatory subunit 3a (gamma) #=GS A0A0R4IYS3/7-134 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GS A0A182SUI3/322-440 AC A0A182SUI3 #=GS A0A182SUI3/322-440 OS Anopheles maculatus #=GS A0A182SUI3/322-440 DE Uncharacterized protein #=GS A0A182SUI3/322-440 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles maculatus group; Anopheles maculatus; #=GS A0A182Y150/722-839 AC A0A182Y150 #=GS A0A182Y150/722-839 OS Anopheles stephensi #=GS A0A182Y150/722-839 DE Uncharacterized protein #=GS A0A182Y150/722-839 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles stephensi; #=GS A0A182HWY0/486-602 AC A0A182HWY0 #=GS A0A182HWY0/486-602 OS Anopheles arabiensis #=GS A0A182HWY0/486-602 DE Uncharacterized protein #=GS A0A182HWY0/486-602 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles arabiensis; #=GS A0A182M794/521-637 AC A0A182M794 #=GS A0A182M794/521-637 OS Anopheles culicifacies #=GS A0A182M794/521-637 DE Uncharacterized protein #=GS A0A182M794/521-637 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles culicifacies; #=GS A0A182NHQ5/727-842 AC A0A182NHQ5 #=GS A0A182NHQ5/727-842 OS Anopheles dirus #=GS A0A182NHQ5/727-842 DE Uncharacterized protein #=GS A0A182NHQ5/727-842 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; leucosphyrus group; leucosphyrus subgroup; Anopheles dirus; #=GS A0A182V4G9/738-856 AC A0A182V4G9 #=GS A0A182V4G9/738-856 OS Anopheles merus #=GS A0A182V4G9/738-856 DE Uncharacterized protein #=GS A0A182V4G9/738-856 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles merus; #=GS A0A182RMJ0/544-660 AC A0A182RMJ0 #=GS A0A182RMJ0/544-660 OS Anopheles funestus #=GS A0A182RMJ0/544-660 DE Uncharacterized protein #=GS A0A182RMJ0/544-660 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; funestus group; funestus subgroup; Anopheles funestus; #=GS A0A182PHH2/754-872 AC A0A182PHH2 #=GS A0A182PHH2/754-872 OS Anopheles epiroticus #=GS A0A182PHH2/754-872 DE Uncharacterized protein #=GS A0A182PHH2/754-872 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles epiroticus; #=GS B4ICV4/5-125 AC B4ICV4 #=GS B4ICV4/5-125 OS Drosophila sechellia #=GS B4ICV4/5-125 DE GM16734 #=GS B4ICV4/5-125 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS B4Q624/5-125 AC B4Q624 #=GS B4Q624/5-125 OS Drosophila simulans #=GS B4Q624/5-125 DE GD23016 #=GS B4Q624/5-125 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B3N7N9/11-135 AC B3N7N9 #=GS B3N7N9/11-135 OS Drosophila erecta #=GS B3N7N9/11-135 DE Uncharacterized protein #=GS B3N7N9/11-135 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS A0A0J9TCG3/11-135 AC A0A0J9TCG3 #=GS A0A0J9TCG3/11-135 OS Drosophila simulans #=GS A0A0J9TCG3/11-135 DE Uncharacterized protein, isoform A #=GS A0A0J9TCG3/11-135 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B4P2C7/11-135 AC B4P2C7 #=GS B4P2C7/11-135 OS Drosophila yakuba #=GS B4P2C7/11-135 DE Uncharacterized protein #=GS B4P2C7/11-135 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS A0A182UZJ9/541-659 AC A0A182UZJ9 #=GS A0A182UZJ9/541-659 OS Anopheles merus #=GS A0A182UZJ9/541-659 DE Uncharacterized protein #=GS A0A182UZJ9/541-659 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles merus; #=GS A0A0R4IUJ2/19-146 AC A0A0R4IUJ2 #=GS A0A0R4IUJ2/19-146 OS Danio rerio #=GS A0A0R4IUJ2/19-146 DE Phosphoinositide-3-kinase, regulatory subunit 3a (gamma) #=GS A0A0R4IUJ2/19-146 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GS Q6PBV3/7-134 AC Q6PBV3 #=GS Q6PBV3/7-134 OS Danio rerio #=GS Q6PBV3/7-134 DE Zgc:73230 #=GS Q6PBV3/7-134 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GF SQ 24 Q7KTZ2/316-422 V--------------SNQPHSNEALWLLKDAKRRNAEEMLKGAPSGTFLIRAR---DAGH--YALSIACKNIVQ----HCLIYETSTGFGFAAPYNIYATLKSLVEHYANNSLEEHNDTLTTTLRWPVLY------- O18683/326-432 V--------------SNQPHSNEALWLLKDAKRRNAEEMLKGAPSGTFLIRAR---DAGH--YALSIACKNIVQ----HCLIYETSTGFGFAAPYNIYATLKSLVEHYANNSLEEHNDTLTTTLRWPVLY------- M9PAY7/17-123 V--------------SNQPHSNEALWLLKDAKRRNAEEMLKGAPSGTFLIRAR---DAGH--YALSIACKNIVQ----HCLIYETSTGFGFAAPYNIYATLKSLVEHYANNSLEEHNDTLTTTLRWPVLY------- T1EIM1/2-108 ---------------SRNKNDLEAPWFHGDISRDEINDLLMGTPDGTFIVRHSTTKDENE-PYTLTLRKGGANK----LIKICQKNGYWYLSAS-TQFASVYELIEHYTKHSLVHFNDSLDITLQYPL--------- A7UTR8/474-591 ----------LITDPNTPQELRDAEWYWGKISRDVAKEKMMDAPDGSFLVRDA-INDAGE--FTLVLKKDGTDR----PIKIYHKNGKYGFTQE-CTFESLVGMINEFRTTTLKEYNTILDISLLYPISRFEDESL- E9HA70/275-390 -----------------GPAPPVTYWLIPDCTRPDAERLLSNKADGTFLIRRS---AAGSAPFALSIAYRRVDKG-VGHILIHRSERGFGFTEPYLLFPTLNDLVVYYAGHSLEEHNPQLTTTLAHPLHGPQPLESN E9G0D1/307-421 ------------------VHADSQYWLLPDCTRPDAERFLTGKADGTFLIRRS----AGSAPFALSIACSNVKKTPVGHILIHRSERGFGFTEPYLLFPTLNDLVVYYAGHSLEELNPLITTTLAHPLHGPQPPEGN A0A0R4IYS3/7-134 AGTVNSTDDHLQTQREPSDLLQDAEWYWADISREEVNEILHGMPDGAFLVRDASCKVQGE--YTLTVRNNGTNK----LIRILHQEGKFGFSEP-LTFSSVPELISFYRHRSLVHYNTSLDVTLAYPVTHCNTDL-- A0A182SUI3/322-440 ---------PLNTDPDTPQELRDAEWYWGKISRDVAKEKMMDAQDGSFLVRDA-INDAGE--YTLVLKKDGTDR----PIKIYHKNGKYGFTQD-CTFESLVGMINEFRTTTLKEYNTILDISLLYPVSRFEDESL- A0A182Y150/722-839 ----------LVTDPDTPQELRDAEWYWGKISRDVAKEKMMDAQDGSFLVRDA-INDAGE--YTLVLKKDGTDR----PIKIYHKNGKYGFTQD-CTFESLVGMINEFRTTTLKEYNTILDISLLYPVSRFEDESL- A0A182HWY0/486-602 -----------ITDPNTPQELRDAEWYWGKISRDVAKEKMMDAPDGSFLVRDA-INDAGE--FTLVLKKDGTDR----PIKIYHKNGKYGFTQE-CTFESLVGMINEFRTTTLKEYNTILDISLLYPISRFEDESL- A0A182M794/521-637 ----------LVTDPDTPQELRDAEWYWGKISRDVAKEKMMDAQDGSFLVRDA-INDAGE--YTLVLKKDGTDR----PIKIYHKNGKYGFTQE-CTFESLVSMINEFRTTTLKEYNTILDISLLYPISRFEDET-- A0A182NHQ5/727-842 ----------LITDPDTPQELRDAEWYWGKISRDVAKEKMMDAADGSFLVRDA-INDAGE--YTLVLKKDGTDR----PIKIYHKNGKYGFTQE-CTFESLVAMINEFRTTTLKEYNTILDISLLYPISRFEDD--- A0A182V4G9/738-856 ---------SLITDPNTPQELRDAEWYWGKISRDMAKEKMMDAPDGSFLVRDA-INDAGE--FTLVLKKDGTDR----PIKIYHKNGKYGFTQE-CTFESLVAMINEFRTTTLKEYNTILDISLLYPISRFEDESL- A0A182RMJ0/544-660 -----------VTDPDTPQELRDAEWYWGKISRDIAKEKMMDAQDGSFLVRDA-INDAGE--YTLVLKKDGTDR----PIKIYHKNGKYGFTQE-CTFESLVGMINEFRTTTLKEYNTILDISLLYPISRFEDESL- A0A182PHH2/754-872 ---------SLITDPNTPQELRDAEWYWGKISRDVAKEKMMDAPDGSFLVRDA-INDAGE--YTLVLKKDGTDR----PIKIYHKNGKYGFTQE-CTFESLVGMINEFRTTTLKEYNTILDISLLYPISRFEDESL- B4ICV4/5-125 -------APGSLVDPN-EDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDA-LSMKGE--YTLTLMKDGCEK----LIKICHMDRKYGFIET-DLFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRAREDEES B4Q624/5-125 -------APGSLVDPN-EDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDA-LSMKGE--YTLTLMKDGCEK----LIKICHMDRKYGFIET-DLFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRAREDEES B3N7N9/11-135 ---MRPQAPGSLVDPN-EDELRMAPWYWGRISREEAKSILNGKPDGSFLVRDA-LSMKGE--YTLTLMKDGIEK----LIKICHMDHKYGFIET-NLFNSVVEMINYYKENSLSMYNKTLDITLSNPILRAREDEES A0A0J9TCG3/11-135 ---MRPQAPGSLVDPN-EDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDA-LSMKGE--YTLTLMKDGCEK----LIKICHMDRKYGFIET-DLFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRAREDEES B4P2C7/11-135 ---MRPQAPGSLVDPN-EEELRMAPWYWGRISREVAKSILHGKPDGSFLVRDA-LSMKGE--YTLTLMKDGSEK----LIKICHMDRKYGFIEK-DLFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRAREDEES A0A182UZJ9/541-659 ---------SLITDPNTPQELRDAEWYWGKISRDMAKEKMMDAPDGSFLVRDA-INDAGE--FTLVLKKDGTDR----PIKIYHKNGKYGFTQE-CTFESLVAMINEFRTTTLKEYNTILDISLLYPISRFEDESL- A0A0R4IUJ2/19-146 AGTVNSTDDHLQTQREPSDLLQDAEWYWADISREEVNEILHGMPDGAFLVRDASCKVQGE--YTLTVRNNGTNK----LIRILHQEGKFGFSEP-LTFSSVPELISFYRHRSLVHYNTSLDVTLAYPVTHCNTDL-- Q6PBV3/7-134 AGTVNSTDDHLQTQREPSDLLQDAEWYWADISREEVNEILHGMPDGAFLVRDASCKVQGE--YTLTVRNNGTNK----LIRILHQEGKFGFSEP-LTFSSVPELISFYRNRSLVHYNTSLDVTLAYPVTHCNTDL-- #=GC scorecons 00000000001122232344544739655556943755373646795987955022358600769464456446000046595635456884540348466446744754469346944866693496342223210 #=GC scorecons_70 _______________________*_*______*__*___*___***_****_______*___***________*_____*_*______***______*_**__**__*___**__**__*__**__*__________ #=GC scorecons_80 _______________________*_*______*___________**_****_______*___*_*________________*_______**______*______*__*____*___*__*___*__*__________ #=GC scorecons_90 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