# STOCKHOLM 1.0 #=GF ID 3.30.460.10/FF/000038 #=GF DE Topoisomerase-related function protein-like protein #=GF AC 3.30.460.10/FF/000038 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 93.698 #=GS G5EFL0/93-204 AC G5EFL0 #=GS G5EFL0/93-204 OS Caenorhabditis elegans #=GS G5EFL0/93-204 DE Poly(A) RNA polymerase gld-4 #=GS G5EFL0/93-204 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS G5EFL0/93-204 DR GO; GO:0004652; GO:0005737; GO:0005844; GO:0006378; GO:0043186; #=GS G5EFL0/93-204 DR EC; 2.7.7.19; #=GS Q57VP5/337-446 AC Q57VP5 #=GS Q57VP5/337-446 OS Trypanosoma brucei brucei TREU927 #=GS Q57VP5/337-446 DE DNA polymerase sigma, putative #=GS Q57VP5/337-446 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q57VP5/337-446 DR GO; GO:0003676; GO:0005634; GO:0016779; #=GS C7G070/459-574 AC C7G070 #=GS C7G070/459-574 OS Dictyostelium discoideum #=GS C7G070/459-574 DE PAP/25A-associated domain-containing protein #=GS C7G070/459-574 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS A2DSJ4/54-168 AC A2DSJ4 #=GS A2DSJ4/54-168 OS Trichomonas vaginalis #=GS A2DSJ4/54-168 DE Nucleotidyltransferase domain containing protein #=GS A2DSJ4/54-168 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS H3GMU5/136-242 AC H3GMU5 #=GS H3GMU5/136-242 OS Phytophthora ramorum #=GS H3GMU5/136-242 DE Uncharacterized protein #=GS H3GMU5/136-242 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora ramorum; #=GS A4HT94/420-529 AC A4HT94 #=GS A4HT94/420-529 OS Leishmania infantum #=GS A4HT94/420-529 DE Topoisomerase-related function protein-like protein #=GS A4HT94/420-529 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS F1A378/316-430 AC F1A378 #=GS F1A378/316-430 OS Dictyostelium purpureum #=GS F1A378/316-430 DE Uncharacterized protein #=GS F1A378/316-430 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS A4H521/402-511 AC A4H521 #=GS A4H521/402-511 OS Leishmania braziliensis #=GS A4H521/402-511 DE Topoisomerase-related function protein-like protein #=GS A4H521/402-511 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A0A1G4I9S7/337-446 AC A0A1G4I9S7 #=GS A0A1G4I9S7/337-446 OS Trypanosoma equiperdum #=GS A0A1G4I9S7/337-446 DE NPAPL #=GS A0A1G4I9S7/337-446 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; #=GS G4YH03/145-251 AC G4YH03 #=GS G4YH03/145-251 OS Phytophthora sojae strain P6497 #=GS G4YH03/145-251 DE Uncharacterized protein #=GS G4YH03/145-251 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora sojae; #=GS H3E5C1/165-279 AC H3E5C1 #=GS H3E5C1/165-279 OS Pristionchus pacificus #=GS H3E5C1/165-279 DE Uncharacterized protein #=GS H3E5C1/165-279 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS Q4QIM1/417-526 AC Q4QIM1 #=GS Q4QIM1/417-526 OS Leishmania major #=GS Q4QIM1/417-526 DE Topoisomerase-related function protein-like protein #=GS Q4QIM1/417-526 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS A0A088S2S2/191-300 AC A0A088S2S2 #=GS A0A088S2S2/191-300 OS Leishmania panamensis #=GS A0A088S2S2/191-300 DE Topoisomerase-related function protein-like protein #=GS A0A088S2S2/191-300 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; #=GS E9AL83/414-523 AC E9AL83 #=GS E9AL83/414-523 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AL83/414-523 DE Topoisomerase-related function protein-like protein #=GS E9AL83/414-523 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS A0A3S5H5Z3/419-528 AC A0A3S5H5Z3 #=GS A0A3S5H5Z3/419-528 OS Leishmania donovani #=GS A0A3S5H5Z3/419-528 DE Topoisomerase-related function protein-like protein #=GS A0A3S5H5Z3/419-528 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A0A1E1IPS5/404-513 AC A0A1E1IPS5 #=GS A0A1E1IPS5/404-513 OS Leishmania guyanensis #=GS A0A1E1IPS5/404-513 DE Putative topoisomerase-related function protein-like protein #=GS A0A1E1IPS5/404-513 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; #=GS A0A261CES0/98-209 AC A0A261CES0 #=GS A0A261CES0/98-209 OS Caenorhabditis latens #=GS A0A261CES0/98-209 DE Uncharacterized protein #=GS A0A261CES0/98-209 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; #=GS A0A2G5VJ09/95-206 AC A0A2G5VJ09 #=GS A0A2G5VJ09/95-206 OS Caenorhabditis nigoni #=GS A0A2G5VJ09/95-206 DE Uncharacterized protein #=GS A0A2G5VJ09/95-206 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A8XFG3/97-208 AC A8XFG3 #=GS A8XFG3/97-208 OS Caenorhabditis briggsae #=GS A8XFG3/97-208 DE Protein CBR-GLD-4 #=GS A8XFG3/97-208 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS A2FB50/54-161 AC A2FB50 #=GS A2FB50/54-161 OS Trichomonas vaginalis #=GS A2FB50/54-161 DE PAP/25A associated domain containing protein #=GS A2FB50/54-161 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS A2ETQ1/46-155 AC A2ETQ1 #=GS A2ETQ1/46-155 OS Trichomonas vaginalis #=GS A2ETQ1/46-155 DE Nucleotidyltransferase domain containing protein #=GS A2ETQ1/46-155 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS A2EPB8/46-155 AC A2EPB8 #=GS A2EPB8/46-155 OS Trichomonas vaginalis #=GS A2EPB8/46-155 DE Uncharacterized protein #=GS A2EPB8/46-155 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS A0A3P3YYK9/402-511 AC A0A3P3YYK9 #=GS A0A3P3YYK9/402-511 OS Leishmania braziliensis MHOM/BR/75/M2904 #=GS A0A3P3YYK9/402-511 DE Topoisomerase-related_function_protein-like_protein #=GS A0A3P3YYK9/402-511 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS E9B969/419-528 AC E9B969 #=GS E9B969/419-528 OS Leishmania donovani BPK282A1 #=GS E9B969/419-528 DE Topoisomerase-related function protein-like protein #=GS E9B969/419-528 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GF SQ 24 G5EFL0/93-204 PNEIESRLRTKVFEKVRDSVLRRWKQKTIKISMFGSLRTNLFLPTSDIDVLVECDDWVGTPGD-----WLAETARGLEADNIAES---VMVYGGAFVPIVKMVDRDTRLSIDISFNTV-----QG Q57VP5/337-446 PTEAEIAIRCLVEAEVVTIAKQLWPK--CEPVVFGSMATGLLLPLSDVDITILNVD--VPTEE-----ALRLLAREISLSGICNTAY-PQLVLKAKVPLLKFQHCGSLLDVDISINAR-----DG C7G070/459-574 PSELESRIRQKIIRDLDAIVKSNWPK--ANVVVFGSFSSNLFIPSSDIDIQISGINNAESVNKYN-QNPIRDLFDIIIRNHQDSFIN-VRNIFGAKVPIIKMTSSHSHYNIDICFDTP-----NG A2DSJ4/54-168 PTLEEKYVRLRIYKNIQECITKIYPL--AKVILFGSNSTDSNLPFSDIDLSVVIKN--LIIDDT--LEELYFIGRYLKLSGVISQ---FQVI-NAKVPIVKATDSGFRLPIDIGIVTQLSDEDND H3GMU5/136-242 PTEHELSSRAELIDEMRQLVKELWPD--ATVETFGSHYTQMFLPQSDIDMVLFGVP--AG------KAPLFKLAQCLEEKELVSY---LEVIDKARIPIVKMVHKASDIHVDVSFNVA-----GG A4HT94/420-529 PTEAEVTMRRYIEKDIGRLVDRLWPG--SSVLVYGSMYTHLLLPLSDLDITLLDVP--VPAEE-----ALTSLAKEISSAGLCENVY-PQVILKTKVPLIKFVHKGSLIDVDISVGAV-----DG F1A378/316-430 PNEYEIRVRQKIIKEIETIVKENWPK--AKVVIFGSFSSNLFIPSSDIDIQISDIN--EGIDRYSFQNPIRDFHSILIKNHQSSFYN-VRLISGAKIPIIKMTSVHTQYNIDICFDTP-----SG A4H521/402-511 PTEAEVAMRRYIEKKIGLLVDRLWPG--SSVLVYGSMYTHLLLPLSDLDVTLLDVP--VPVEE-----ALSALAKEISNAGLCENAY-PQVILKTKVPLIKFVHKGSLIDVDISVGAV-----DG A0A1G4I9S7/337-446 PTEAEIAIRCLVEAEVVTIAKQLWPK--CEPVVFGSMATGLLLPLSDVDITILNVD--VPTEE-----ALRLLAREISLSGICNTAY-PQLVLKAKVPLLKFQHCGSLLDVDISINAR-----DG G4YH03/145-251 PTEQELSSRAELIEEMREIVKGLWPE--ATVETFGSHYTQMFLPQSDIDMVLFGVP--EG------KAPLFKLAQCLEEKELVSY---LEVIDKARIPIVKMVHKASDIHVDVSFNVA-----GG H3E5C1/165-279 PTRLETATRYKVFEKVREKIVNMWAPLPVKVSVFGSLRTRLFLPSSDIDILVECLEWTQYTDV-----QLNTNVMQPTMHYLKDHFDIVSFHPAAFVPILKFSDRGTRLNIDISFNTV-----QG Q4QIM1/417-526 PTEAEVTMRRYIEKDIGRLADRLWPG--SSVLVYGSMYTHLLLPLSDLDITLLDVP--VSAEE-----ALTSLAKEISSAGMCENVY-PQVILKTKVPLIKFVHKGSLIDVDISVGAV-----DG A0A088S2S2/191-300 PTEAEVAMRRYIEKKIGLLVDRLWPG--SSVLVYGSMYTHLLLPLSDLDVTLLDVP--VPVEE-----ALSALAKEISNAGLCENAY-PQVILKTKVPLIKFVHKGSLIDVDISVGAV-----DG E9AL83/414-523 PTEAEVTMRRYIEKDIGRLVDRLWPG--SSVLVYGSMYTHLLLPLSDLDITLLDVP--VPAEE-----ALTSLAKEISSAGLCENVY-PQVILKTKVPLIKFIHKGSLIDVDISVGAV-----DG A0A3S5H5Z3/419-528 PTEAEVTMRRYIEKDIGRLVDRLWPG--SSVLVYGSMYTHLLLPLSDLDITLLDVP--VPAEE-----ALTSLAKEISSAGLCENVY-PQVILKTKVPLIKFVHKGSLIDVDISVGAV-----DG A0A1E1IPS5/404-513 PTEAEVAMRRYIEKKIGLLVDRLWPG--SSVLVYGSMYTHLLLPLSDLDVTLLDVP--VPVEE-----ALSALAKEISNAGLCENAY-PQVILKTKVPLIKFVHKGSLIDVDISVGAV-----DG A0A261CES0/98-209 PNEIESRLRTKVYEKVRDSVLQRWKHKAIKISMFGSLRTNLFLPTSDIDVLVECEDWVGSSSD-----WLAETARGLEMDNIAES---VMVYGGAYVPIVKMVDRDTRLSIDISFNTV-----QG A0A2G5VJ09/95-206 PNEIEVRLRTKVYEKVRDSVSQRWQHKPIKISMFGSLRTNLFLPTSDIDVLVECDDWVGTPGD-----WLGETARGLENDNIAES---VTVFGGAFVPIVKMVDRDTRLSIDISFNTV-----QG A8XFG3/97-208 PNEIEVRLRTKVYEKVRDSVSQRWQHKPIKISMFGSLRTNLFLPTSDIDVLVECDDWVGTPGD-----WLGETARGLENDNIAES---VTVFGGAFVPIVKMVDRDTRLSIDISFNTV-----QG A2FB50/54-161 PTEEEKHLRYLVIKRFRVAINQLWPN--AKVICHGSTATGTFLPNGDLDFCVLGAP--SGNDED----LLTELNDHLQALQVVSN---SAVI-KAKCPIISGTEKPFNFKIDISINNE-----NG A2ETQ1/46-155 PTTQEELSRYLTVRKFANFIENLFPP--CSVVAQGSTGTDTYLPTSDIDLIITNLP--ETEDGN---HLLKKLSKDFWKSQLVVQ---SFVIPKAKVPIIKCVERVYGYHLDICIGNI-----NG A2EPB8/46-155 PSESEELSRLLTIRRFVNFIEEYFRP--CIVVTQGSSATDTFLPTSDIDLIVTNLP--DIQDEV---RILKNITKLFWQHQLIVQ---GFVIPGAKVPIAKCIDRAYGYNIDICIGNA-----NG A0A3P3YYK9/402-511 PTEAEVAMRRYIEKKIGLLVDRLWPG--SSVLVYGSMYTHLLLPLSDLDVTLLDVP--VPVEE-----ALSALAKEISNAGLCENAY-PQVILKTKVPLIKFVHKGSLIDVDISVGAV-----DG E9B969/419-528 PTEAEVTMRRYIEKDIGRLVDRLWPG--SSVLVYGSMYTHLLLPLSDLDITLLDVP--VPAEE-----ALTSLAKEISSAGLCENVY-PQVILKTKVPLIKFVHKGSLIDVDISVGAV-----DG #=GC scorecons 96639334933535554336344753004464469943746589389695353344003324400000383355535333453431104365256579668455544344698655540000048 #=GC scorecons_70 *_*_*___*__________*___*______*___**__*___**_****____________________*____________________*___*_***_*_________****__________* #=GC scorecons_80 *___*___*______________*__________**__*___**_**_*____________________*__________________________**__*__________**___________* #=GC scorecons_90 *___*___*_________________________**_______*_**_*________________________________________________*__*__________**___________* //