# STOCKHOLM 1.0 #=GF ID 3.30.450.20/FF/000096 #=GF DE High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 #=GF AC 3.30.450.20/FF/000096 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 67.872 #=GS Q6NNF2/313-418 AC Q6NNF2 #=GS Q6NNF2/313-418 OS Drosophila melanogaster #=GS Q6NNF2/313-418 DE High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 #=GS Q6NNF2/313-418 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q6NNF2/313-418 DR GO; GO:0004115; GO:0007498; GO:0046058; GO:0070374; GO:1903206; #=GS Q6NNF2/313-418 DR EC; 3.1.4.53; #=GS Q8MLR1/205-309 AC Q8MLR1 #=GS Q8MLR1/205-309 OS Drosophila melanogaster #=GS Q8MLR1/205-309 DE Phosphodiesterase 8, isoform D #=GS Q8MLR1/205-309 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS E1JGU6/313-418 AC E1JGU6 #=GS E1JGU6/313-418 OS Drosophila melanogaster #=GS E1JGU6/313-418 DE Phosphodiesterase 8, isoform N #=GS E1JGU6/313-418 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS A0A139WFF3/342-454 AC A0A139WFF3 #=GS A0A139WFF3/342-454 OS Tribolium castaneum #=GS A0A139WFF3/342-454 DE Phosphodiesterase #=GS A0A139WFF3/342-454 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS A0A139WF42/200-312 AC A0A139WF42 #=GS A0A139WF42/200-312 OS Tribolium castaneum #=GS A0A139WF42/200-312 DE Phosphodiesterase #=GS A0A139WF42/200-312 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS Q7QJ01/338-439 AC Q7QJ01 #=GS Q7QJ01/338-439 OS Anopheles gambiae #=GS Q7QJ01/338-439 DE 3',5'-cyclic-nucleotide phosphodiesterase #=GS Q7QJ01/338-439 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS A0A084VQY3/223-323 AC A0A084VQY3 #=GS A0A084VQY3/223-323 OS Anopheles sinensis #=GS A0A084VQY3/223-323 DE AGAP007163-PA-like protein #=GS A0A084VQY3/223-323 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Anopheles; Laticorn; Myzorhynchus; hyrcanus group; Anopheles sinensis; #=GS W5J8B3/374-475 AC W5J8B3 #=GS W5J8B3/374-475 OS Anopheles darlingi #=GS W5J8B3/374-475 DE Camp-specific cyclic nucleotide phosphodiesterase #=GS W5J8B3/374-475 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Nyssorhynchus; darlingi group; Anopheles darlingi; #=GS A0A182Y2P7/303-403 AC A0A182Y2P7 #=GS A0A182Y2P7/303-403 OS Anopheles stephensi #=GS A0A182Y2P7/303-403 DE Uncharacterized protein #=GS A0A182Y2P7/303-403 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles stephensi; #=GS A0A182SHZ1/16-117 AC A0A182SHZ1 #=GS A0A182SHZ1/16-117 OS Anopheles maculatus #=GS A0A182SHZ1/16-117 DE Uncharacterized protein #=GS A0A182SHZ1/16-117 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles maculatus group; Anopheles maculatus; #=GS A0A182IU06/458-558 AC A0A182IU06 #=GS A0A182IU06/458-558 OS Anopheles atroparvus #=GS A0A182IU06/458-558 DE Uncharacterized protein #=GS A0A182IU06/458-558 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Anopheles; Angusticorn; Anopheles; maculipennis group; Anopheles atroparvus; #=GS A0A182KH22/30-135 AC A0A182KH22 #=GS A0A182KH22/30-135 OS Anopheles christyi #=GS A0A182KH22/30-135 DE Uncharacterized protein #=GS A0A182KH22/30-135 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles christyi; #=GS A0A182NJW4/477-577 AC A0A182NJW4 #=GS A0A182NJW4/477-577 OS Anopheles dirus #=GS A0A182NJW4/477-577 DE Uncharacterized protein #=GS A0A182NJW4/477-577 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; leucosphyrus group; leucosphyrus subgroup; Anopheles dirus; #=GS A0A182WJV1/471-571 AC A0A182WJV1 #=GS A0A182WJV1/471-571 OS Anopheles minimus #=GS A0A182WJV1/471-571 DE Uncharacterized protein #=GS A0A182WJV1/471-571 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; minimus group; Anopheles minimus; #=GS A0A182FGD7/504-605 AC A0A182FGD7 #=GS A0A182FGD7/504-605 OS Anopheles albimanus #=GS A0A182FGD7/504-605 DE Uncharacterized protein #=GS A0A182FGD7/504-605 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Nyssorhynchus; Anopheles albimanus; #=GS A0A1W4ULF6/450-555 AC A0A1W4ULF6 #=GS A0A1W4ULF6/450-555 OS Drosophila ficusphila #=GS A0A1W4ULF6/450-555 DE high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1 #=GS A0A1W4ULF6/450-555 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4ULL4/450-555 AC A0A1W4ULL4 #=GS A0A1W4ULL4/450-555 OS Drosophila ficusphila #=GS A0A1W4ULL4/450-555 DE high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X2 #=GS A0A1W4ULL4/450-555 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4UA72/304-409 AC A0A1W4UA72 #=GS A0A1W4UA72/304-409 OS Drosophila ficusphila #=GS A0A1W4UA72/304-409 DE high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X8 #=GS A0A1W4UA72/304-409 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4UA64/450-555 AC A0A1W4UA64 #=GS A0A1W4UA64/450-555 OS Drosophila ficusphila #=GS A0A1W4UA64/450-555 DE high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X3 #=GS A0A1W4UA64/450-555 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4U9K6/304-409 AC A0A1W4U9K6 #=GS A0A1W4U9K6/304-409 OS Drosophila ficusphila #=GS A0A1W4U9K6/304-409 DE high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X7 #=GS A0A1W4U9K6/304-409 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4UNC3/319-424 AC A0A1W4UNC3 #=GS A0A1W4UNC3/319-424 OS Drosophila ficusphila #=GS A0A1W4UNC3/319-424 DE high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X6 #=GS A0A1W4UNC3/319-424 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS B4I8R1/313-418 AC B4I8R1 #=GS B4I8R1/313-418 OS Drosophila sechellia #=GS B4I8R1/313-418 DE GM16033 #=GS B4I8R1/313-418 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS A0A1W4UA69/319-424 AC A0A1W4UA69 #=GS A0A1W4UA69/319-424 OS Drosophila ficusphila #=GS A0A1W4UA69/319-424 DE high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X5 #=GS A0A1W4UA69/319-424 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4U9K2/319-424 AC A0A1W4U9K2 #=GS A0A1W4U9K2/319-424 OS Drosophila ficusphila #=GS A0A1W4U9K2/319-424 DE high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X4 #=GS A0A1W4U9K2/319-424 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS B3NPQ1/313-418 AC B3NPQ1 #=GS B3NPQ1/313-418 OS Drosophila erecta #=GS B3NPQ1/313-418 DE Uncharacterized protein #=GS B3NPQ1/313-418 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS A0A0J9U9F1/313-418 AC A0A0J9U9F1 #=GS A0A0J9U9F1/313-418 OS Drosophila simulans #=GS A0A0J9U9F1/313-418 DE Uncharacterized protein #=GS A0A0J9U9F1/313-418 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B4P9Q8/314-419 AC B4P9Q8 #=GS B4P9Q8/314-419 OS Drosophila yakuba #=GS B4P9Q8/314-419 DE Uncharacterized protein #=GS B4P9Q8/314-419 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GF SQ 27 Q6NNF2/313-418 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- Q8MLR1/205-309 ---QALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- E1JGU6/313-418 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A139WFF3/342-454 ATCQSVYAALDKCKDVVIITDDSYRCQYANRSCEKYLSIKPDEILGKTLQEQLAYDALQITTMGSSLHRGREWNGALTLKKKSNEPILTSCRAVPISCAGRLPTHFVMVLDTS A0A139WF42/200-312 ATCQSVYAALDKCKDVVIITDDSYRCQYANRSCEKYLSIKPDEILGKTLQEQLAYDALQITTMGSSLHRGREWNGALTLKKKSNEPILTSCRAVPISCAGRLPTHFVMVLDTS Q7QJ01/338-439 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLSDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTH-------- A0A084VQY3/223-323 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKMDEIVGRSLSDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPT--------- W5J8B3/374-475 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLGDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTH-------- A0A182Y2P7/303-403 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPT--------- A0A182SHZ1/16-117 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTH-------- A0A182IU06/458-558 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKMDEIVGRSLNDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPT--------- A0A182KH22/30-135 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLSDLVTAD---ISNILSHTSRYKDYDGYLSTRRKSQESSQIHVRAVPVSCIGRNPTHLVLI---- A0A182NJW4/477-577 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPT--------- A0A182WJV1/471-571 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPT--------- A0A182FGD7/504-605 STQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLGDLVTAD---ISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTH-------- A0A1W4ULF6/450-555 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A1W4ULL4/450-555 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A1W4UA72/304-409 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A1W4UA64/450-555 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A1W4U9K6/304-409 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A1W4UNC3/319-424 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- B4I8R1/313-418 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A1W4UA69/319-424 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A1W4U9K2/319-424 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- B3NPQ1/313-418 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- A0A0J9U9F1/313-418 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- B4P9Q8/314-419 --QQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD---LSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD-- #=GC scorecons 22697797997847869699994794999997598597776999667494855559000676745544548767949858899795545779699869795499522222300 #=GC scorecons_70 __**********_**_******_**_******_**_*********_*_*_*____*___**_*_______**_**_**_******____***_***_***__**_________ #=GC scorecons_80 ___*********__*_*_****_**_******_**_***__***____*_*____*____*_*_______*__**_**_******____*_*_***_***__**_________ #=GC scorecons_90 ___*__*_**______*_****__*_*****__*__*____***____*______*__________________*_**___**_*______*_**__*_*__**_________ //