# STOCKHOLM 1.0 #=GF ID 3.30.40.10/FF/000548 #=GF DE Putative Histone-lysine N-methyltransferase MLL3 #=GF AC 3.30.40.10/FF/000548 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 74.358 #=GS Q9W1H0/330-395 AC Q9W1H0 #=GS Q9W1H0/330-395 OS Drosophila melanogaster #=GS Q9W1H0/330-395 DE HL01030p #=GS Q9W1H0/330-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9W1H0/330-395 DR GO; GO:0003682; GO:0005700; GO:0007474; GO:0008230; GO:0008270; GO:0008586; GO:0018990; GO:0030374; GO:0035076; GO:0042393; GO:0044666; GO:0045944; GO:0051568; GO:0071390; GO:1900114; #=GS A0A0B4LGG6/330-395 AC A0A0B4LGG6 #=GS A0A0B4LGG6/330-395 OS Drosophila melanogaster #=GS A0A0B4LGG6/330-395 DE Lost PHDs of trr, isoform B #=GS A0A0B4LGG6/330-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS A0A0B4LGG6/330-395 DR GO; GO:0003682; GO:0005700; GO:0007474; GO:0008230; GO:0008270; GO:0008586; GO:0018990; GO:0030374; GO:0035076; GO:0042393; GO:0044666; GO:0045944; GO:0051568; GO:0071390; GO:1900114; #=GS W4ZE73/584-650 AC W4ZE73 #=GS W4ZE73/584-650 OS Strongylocentrotus purpuratus #=GS W4ZE73/584-650 DE Histone-lysine N-methyltransferase #=GS W4ZE73/584-650 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS A0A139WMS0/484-557 AC A0A139WMS0 #=GS A0A139WMS0/484-557 OS Tribolium castaneum #=GS A0A139WMS0/484-557 DE Histone-lysine N-methyltransferase #=GS A0A139WMS0/484-557 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS D6W9D4/484-557 AC D6W9D4 #=GS D6W9D4/484-557 OS Tribolium castaneum #=GS D6W9D4/484-557 DE Histone-lysine N-methyltransferase #=GS D6W9D4/484-557 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS E9GJI9/589-653 AC E9GJI9 #=GS E9GJI9/589-653 OS Daphnia pulex #=GS E9GJI9/589-653 DE Uncharacterized protein #=GS E9GJI9/589-653 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS A0A0P5E6T6/589-653 AC A0A0P5E6T6 #=GS A0A0P5E6T6/589-653 OS Daphnia magna #=GS A0A0P5E6T6/589-653 DE Putative Histone-lysine N-methyltransferase MLL3 #=GS A0A0P5E6T6/589-653 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia magna; #=GS B4GCY5/329-395 AC B4GCY5 #=GS B4GCY5/329-395 OS Drosophila persimilis #=GS B4GCY5/329-395 DE GL11176 #=GS B4GCY5/329-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila persimilis; #=GS B4I8W1/323-389 AC B4I8W1 #=GS B4I8W1/323-389 OS Drosophila sechellia #=GS B4I8W1/323-389 DE GM16061 #=GS B4I8W1/323-389 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS B3NQ20/330-395 AC B3NQ20 #=GS B3NQ20/330-395 OS Drosophila erecta #=GS B3NQ20/330-395 DE Uncharacterized protein #=GS B3NQ20/330-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS Q292Q5/329-395 AC Q292Q5 #=GS Q292Q5/329-395 OS Drosophila pseudoobscura pseudoobscura #=GS Q292Q5/329-395 DE Uncharacterized protein, isoform A #=GS Q292Q5/329-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; #=GS B4PA96/330-395 AC B4PA96 #=GS B4PA96/330-395 OS Drosophila yakuba #=GS B4PA96/330-395 DE Uncharacterized protein #=GS B4PA96/330-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS A0A0J9RL23/330-395 AC A0A0J9RL23 #=GS A0A0J9RL23/330-395 OS Drosophila simulans #=GS A0A0J9RL23/330-395 DE Uncharacterized protein #=GS A0A0J9RL23/330-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS A0A1W4UZS5/330-395 AC A0A1W4UZS5 #=GS A0A1W4UZS5/330-395 OS Drosophila ficusphila #=GS A0A1W4UZS5/330-395 DE histone-lysine N-methyltransferase 2C isoform X4 #=GS A0A1W4UZS5/330-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4UMB3/347-412 AC A0A1W4UMB3 #=GS A0A1W4UMB3/347-412 OS Drosophila ficusphila #=GS A0A1W4UMB3/347-412 DE histone-lysine N-methyltransferase 2C isoform X3 #=GS A0A1W4UMB3/347-412 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4UMU1/366-431 AC A0A1W4UMU1 #=GS A0A1W4UMU1/366-431 OS Drosophila ficusphila #=GS A0A1W4UMU1/366-431 DE histone-lysine N-methyltransferase 2C isoform X1 #=GS A0A1W4UMU1/366-431 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A1W4V1C0/349-414 AC A0A1W4V1C0 #=GS A0A1W4V1C0/349-414 OS Drosophila ficusphila #=GS A0A1W4V1C0/349-414 DE histone-lysine N-methyltransferase 2C isoform X2 #=GS A0A1W4V1C0/349-414 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS A0A3B0JD70/329-394 AC A0A3B0JD70 #=GS A0A3B0JD70/329-394 OS Drosophila guanche #=GS A0A3B0JD70/329-394 DE Blast:Histone-lysine N-methyltransferase 2C #=GS A0A3B0JD70/329-394 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; #=GS B3MCM2/330-395 AC B3MCM2 #=GS B3MCM2/330-395 OS Drosophila ananassae #=GS B3MCM2/330-395 DE Uncharacterized protein #=GS B3MCM2/330-395 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; Drosophila ananassae; #=GS B4MRN9/329-394 AC B4MRN9 #=GS B4MRN9/329-394 OS Drosophila willistoni #=GS B4MRN9/329-394 DE Uncharacterized protein #=GS B4MRN9/329-394 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; #=GS A0A0N8C162/589-653 AC A0A0N8C162 #=GS A0A0N8C162/589-653 OS Daphnia magna #=GS A0A0N8C162/589-653 DE Putative Histone-lysine N-methyltransferase MLL3 #=GS A0A0N8C162/589-653 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia magna; #=GF SQ 21 Q9W1H0/330-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- A0A0B4LGG6/330-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- W4ZE73/584-650 --------QRNKGYCCPICGKAYRHHTTHKVMVQCHLCNRYVHADCDDRTVISKYQQSKAAGQPTPYKCPDCRHR- A0A139WMS0/484-557 TVCDSCYQQRNKGFSCPLCHRAYRAH-AHREMVQCTLCRKFVHGTCDPEADLVTYHQRKEAHPEYEYVCLMCKNL- D6W9D4/484-557 TVCDSCYQQRNKGFSCPLCHRAYRAH-AHREMVQCTLCRKFVHGTCDPEADLVTYHQRKEAHPEYEYVCLMCKNL- E9GJI9/589-653 --------QRNKGVSCPMCGKAYR-H-SQREMSQCTRCRKYVHSGCDPEADRTLVQRKKDMNSDYEYLCPPCKVS- A0A0P5E6T6/589-653 --------QRNKGVCCPLCGKAYR-H-SQREMSQCQRCRKYVHSGCDPEADRGLVQRKKDMHPDYEYLCPPCKVS- B4GCY5/329-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCHKFVHSTCDEEADLTAYHKKKEQNPDYDYICPNCKQNS B4I8W1/323-389 -------QQRNKGFSCPICQKAYRAA-SHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- B3NQ20/330-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- Q292Q5/329-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCHKFVHSTCDEEADLTAYHKKKEQNPDYDYICPNCKQNS B4PA96/330-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- A0A0J9RL23/330-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- A0A1W4UZS5/330-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCHKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- A0A1W4UMB3/347-412 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCHKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- A0A1W4UMU1/366-431 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCHKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- A0A1W4V1C0/349-414 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCHKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSN- A0A3B0JD70/329-394 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCHKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKLN- B3MCM2/330-395 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKELNPDYDYVCPNCKSS- B4MRN9/329-394 --------QRNKGFSCPICQKAYRAA-SHKEMVKCSWCHKFVHSTCDEEADLMAYHKKKEQNPDYDYVCPNCKTN- A0A0N8C162/589-653 --------QRNKGVCCPLCGKAYR-H-SQREMSQCQRCRKYVHSGCDPEADRGLVQRKKDMHPDYEYLCPPCKVS- #=GC scorecons 0000000099999669969479994506777966944958799659947775445666964566759597498340 #=GC scorecons_70 ________*****_*****_****___********__*_*****_**_***____*_***__***_*_**_**___ #=GC scorecons_80 ________*****__**_*_****____*_**__*__*_****__**_***_______*_____*_*_*__**___ #=GC scorecons_90 ________*****__**_*__***_______*__*__*_*_**__**___________*_______*_*__**___ //