# STOCKHOLM 1.0 #=GF ID 3.30.230.60/FF/000001 #=GF DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GF AC 3.30.230.60/FF/000001 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 78.056 #=GS 1y60E00/1-169 AC Q9FA38 #=GS 1y60E00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y60E00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y60E00/1-169 DR CATH; 1y60; E:4002-4169; #=GS 1y60E00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS Q58842/1-152 AC Q58842 #=GS Q58842/1-152 OS Methanocaldococcus jannaschii DSM 2661 #=GS Q58842/1-152 DE Bifunctional enzyme Fae/Hps #=GS Q58842/1-152 DR ORG; Archaea; Euryarchaeota; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus; Methanocaldococcus jannaschii; #=GS Q58842/1-152 DR EC; 4.1.2.43; 4.2.1.147; #=GS Q603E1/2-170 AC Q603E1 #=GS Q603E1/2-170 OS Methylococcus capsulatus str. Bath #=GS Q603E1/2-170 DE Formaldehyde-activating enzyme #=GS Q603E1/2-170 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Methylococcales; Methylococcaceae; Methylococcus; Methylococcus capsulatus; #=GS Q603E1/2-170 DR GO; GO:0003824; GO:0019649; #=GS Q8THA9/1-163 AC Q8THA9 #=GS Q8THA9/1-163 OS Methanosarcina acetivorans C2A #=GS Q8THA9/1-163 DE Bifunctional enzyme Fae/Hps #=GS Q8THA9/1-163 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina acetivorans; #=GS Q8THA9/1-163 DR EC; 4.1.2.43; 4.2.1.147; #=GS 1y60D00/1-169 AC Q9FA38 #=GS 1y60D00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y60D00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y60D00/1-169 DR CATH; 1y60; D:3002-3170; #=GS 1y60D00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS 1y60C00/1-169 AC Q9FA38 #=GS 1y60C00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y60C00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y60C00/1-169 DR CATH; 1y60; C:2002-2169; #=GS 1y60C00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS 1y60B00/1-169 AC Q9FA38 #=GS 1y60B00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y60B00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y60B00/1-169 DR CATH; 1y60; B:1002-1169; #=GS 1y60B00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS 1y60A00/1-169 AC Q9FA38 #=GS 1y60A00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y60A00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y60A00/1-169 DR CATH; 1y60; A:2-169; #=GS 1y60A00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS 1y5yE00/1-169 AC Q9FA38 #=GS 1y5yE00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y5yE00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y5yE00/1-169 DR CATH; 1y5y; E:4002-4159; #=GS 1y5yE00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS 1y5yD00/1-169 AC Q9FA38 #=GS 1y5yD00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y5yD00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y5yD00/1-169 DR CATH; 1y5y; D:3002-3162; #=GS 1y5yD00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS 1y5yC00/1-169 AC Q9FA38 #=GS 1y5yC00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y5yC00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y5yC00/1-169 DR CATH; 1y5y; C:2002-2159; #=GS 1y5yC00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS 1y5yB00/1-169 AC Q9FA38 #=GS 1y5yB00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y5yB00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y5yB00/1-169 DR CATH; 1y5y; B:1002-1162; #=GS 1y5yB00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS 1y5yA00/1-169 AC Q9FA38 #=GS 1y5yA00/1-169 OS Methylorubrum extorquens AM1 #=GS 1y5yA00/1-169 DE 5,6,7,8-tetrahydromethanopterin hydro-lyase #=GS 1y5yA00/1-169 DR CATH; 1y5y; A:2-160; #=GS 1y5yA00/1-169 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Methylobacteriaceae; Methylorubrum; Methylorubrum extorquens; #=GS A0A250KUI9/2-170 AC A0A250KUI9 #=GS A0A250KUI9/2-170 OS Methylocaldum marinum #=GS A0A250KUI9/2-170 DE Formaldehyde-activating enzyme #=GS A0A250KUI9/2-170 DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Methylococcales; Methylococcaceae; Methylocaldum; Methylocaldum marinum; #=GS Q46DY5/1-163 AC Q46DY5 #=GS Q46DY5/1-163 OS Methanosarcina barkeri str. Fusaro #=GS Q46DY5/1-163 DE Bifunctional enzyme Fae/Hps #=GS Q46DY5/1-163 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina barkeri; #=GS Q46DY5/1-163 DR EC; 4.1.2.43; 4.2.1.147; #=GS A0A0E3RCW0/1-163 AC A0A0E3RCW0 #=GS A0A0E3RCW0/1-163 OS Methanosarcina mazei S-6 #=GS A0A0E3RCW0/1-163 DE Bifunctional enzyme Fae/Hps #=GS A0A0E3RCW0/1-163 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina mazei; #=GS A0A0E3RCW0/1-163 DR EC; 4.1.2.43; 4.2.1.147; #=GS A0A0E3NMQ6/1-163 AC A0A0E3NMQ6 #=GS A0A0E3NMQ6/1-163 OS Methanosarcina sp. WH1 #=GS A0A0E3NMQ6/1-163 DE Bifunctional enzyme Fae/Hps #=GS A0A0E3NMQ6/1-163 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WH1; #=GS A0A0E3NJY3/1-163 AC A0A0E3NJY3 #=GS A0A0E3NJY3/1-163 OS Methanosarcina sp. WWM596 #=GS A0A0E3NJY3/1-163 DE Bifunctional enzyme Fae/Hps #=GS A0A0E3NJY3/1-163 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WWM596; #=GS Q8PXE1/1-163 AC Q8PXE1 #=GS Q8PXE1/1-163 OS Methanosarcina mazei Go1 #=GS Q8PXE1/1-163 DE Bifunctional enzyme Fae/Hps #=GS Q8PXE1/1-163 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina mazei; #=GS Q8PXE1/1-163 DR EC; 4.1.2.43; 4.2.1.147; #=GS A0A0F8LR80/1-163 AC A0A0F8LR80 #=GS A0A0F8LR80/1-163 OS Methanosarcina mazei #=GS A0A0F8LR80/1-163 DE Bifunctional enzyme Fae/Hps #=GS A0A0F8LR80/1-163 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina mazei; #=GS A0A0F8LR80/1-163 DR EC; 4.1.2.43; 4.2.1.147; #=GS A0A0E3SNR6/1-163 AC A0A0E3SNR6 #=GS A0A0E3SNR6/1-163 OS Methanosarcina barkeri 3 #=GS A0A0E3SNR6/1-163 DE Bifunctional enzyme Fae/Hps #=GS A0A0E3SNR6/1-163 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina barkeri; #=GF SQ 21 1y60E00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA Q58842/1-152 ----MIKFGEAVLG--NEIKAIVNVALG-KGELIENTFTNALTRGNC----VFANLRPNLIVKPLTLVVPRHNIESEIQDELFQGVIQYAVAKAVAD--------LDLDEDLKVVVSVNV-PEVPITNLNKRKLFQYFYASAKLAINRALNEYPSKEKVKKEKYRALHPLVG-- Q603E1/2-170 GKVNKLLVGEALCGGGNEI-AHIDLIMGPRGSAAETAFANTLTNNKDGFTSLLAVVAPNLLCKPNTVMFNKVTIKNGKQATQMFGPAQRGVAMAVADCVEDGTIPADEADDLFICVGVFIHWLAE----DDAKIQDYNYEATKLAIKRAVAGEPKAADVVARKGSEAHPFAAHN Q8THA9/1-163 ----MFQIGEALMGQGSEL-AHVDLMIGDKGGPVGQAFANGLTQLSAGHTPLLSVIRPNLPPKPSTLIIPKVTVKNMDQAAKIFGPAQSAVAKAVADSVEEGVIPKDQVEDLVVVASVFIHPEAQ----DYNKIYRYNYGATKLAIKRALEGFPDINKVLEESNKSTHAIMG-- 1y60D00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA 1y60C00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA 1y60B00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA 1y60A00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA 1y5yE00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA 1y5yD00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA 1y5yC00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA 1y5yB00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA 1y5yA00/1-169 AKITKVQVGEALVGDGNEV-AHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAA----DDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAANA A0A250KUI9/2-170 GKINKMLVGEALCGGGNEI-AHIDLIMGPRGSAAETAFANCITNNKDGFSSLLAVVAPNLMAKPNTVMFNKVTIKNGKQATQMFGPAQRGVAMAVADCVEDGTIPADEADDIFVCVGVFIHWLAE----DDAKIQDYNYEATKLAIKRAVAGEPKAAEVVAQKGQIEHPFAAHK Q46DY5/1-163 ----MFQIGEALMGQGAEL-AHVDLMIGDKGGPVGQAFANGLTQLSVGHTPLLSVIRPNLPPKPSTLIIPKVTVKNMEQAGKIFGPAQAAVAKAVADSVEEGVISKDQVEEIVIVASVFIHPDAQ----DYNKIYRYNYGATKLAIKRALGGFPDINTVLEESNKSTHAIMG-- A0A0E3RCW0/1-163 ----MFQIGEALMGQGSEL-AHVDLMIGDKGGPVGQAFANGLTQLSAGHTPLLSVIRPNLPPKPSTLIIPKVTVKNMDQAARIFGPAQSAVAKAVADSVEEGVIPKDQVEDLVIVASVFIHPEAQ----DYNKIYRYNYGATKLAIKRALEGFPDIDTVLEESNKSTHAIMG-- A0A0E3NMQ6/1-163 ----MFQIGEALMGQGAEL-AHVDLMIGDKEGPVGQAFANGLTQLSAGHTPLLSVIRPNLPPKPSTLIIPKVTVKNMEQASKIFGPAQSAVAKAVADSVEEGVITKDQAEDLVIVASVFIHPDAQ----DYNKIYRYNYGATKLALKRALEGFPDIDTVLEESNKSTHAIMG-- A0A0E3NJY3/1-163 ----MFQIGEALMGQGAEL-AHVDLMIGDKEGPVGQAFANGLTQLSAGHTPLLSVIRPNLPPKPSTLIIPKVTVKNMEQASKIFGPAQSAVAKAVADSVEEGVITKDQAEDLVIVASVFIHPDAQ----DYNKIYRYNYGATKLALKRALEGFPDIDTVLEESNKSTHAIMG-- Q8PXE1/1-163 ----MFQIGEALMGQGSEL-AHVDLMIGDKGGPVGQAFANGLTQLSAGHTPLLSVIRPNLPPKPSTLIIPKVTVKNMDQAARIFGPAQSAVAKAVADSVEEGVIPKDQVEDLVIVASVFIHPEAQ----DYNKIYRYNYGATKLAIKRALEGFPDIDTVLEESNKSTHAIMG-- A0A0F8LR80/1-163 ----MFQIGEALMGQGSEL-AHVDLMIGDKGGPVGQAFANGLTQLSAGHTPLLSVIRPNLPPKPSTLIIPKVTVKNMDQAARIFGPAQSAVAKAVADSVEEGVIPKDQVEDLVIVASVFIHPEAQ----DYNKIYRYNYGATKLAIKRALEGFPDIDTVLEESNKSTHAIMG-- A0A0E3SNR6/1-163 ----MFQIGEALMGQGAEL-AHVDLMIGDKGGPVGQAFANGLTQLSVGHTPLLSVIRPNLPPKPSTLIIPKVTVKNMDQAGKIFGPAQSAVAKAVADSVEEGVISKDQVEELVIVVSVFIHPDAQ----DYNKIYRYNYGATKLAIKRALEGFPDINTVLEESNKSTHAIMG-- #=GC scorecons 121155669998594759509778867947756565895968654537464886775999649959865587775544974567977946995995947467575495578847566978746740000845985597957899685996574955449466544569655611 #=GC scorecons_70 ______******_*_*_*__*****_**_**_*___**_***_____*_*_**_**_****_**_***__****____**___*****__**_**_*_*_**_*__*__***_*_*_****__*_____*__**__***_******_***_*_*____*_*_____**______ #=GC scorecons_80 ________****_*_*_*__**_**_**__*_____**_*_*_____*___**_**_***__**_**___***_____**___*****__**_**_*_*__*_*__*___**_____****__*_____*__**__***_****_*_**__*_*____*________*______ #=GC scorecons_90 ________***__*___*__*______*_________*_*_*_______________***__**_*____*_______*_____*__*__**_**_*_________*___*______*_*____________*___*_*___**___**____*____*________*______ //