# STOCKHOLM 1.0
#=GF ID 3.20.20.20/FF/000015
#=GF DE Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase
#=GF AC 3.20.20.20/FF/000015
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 85.284
#=GS Q54YD9/311-466_500-652  AC Q54YD9
#=GS Q54YD9/311-466_500-652  OS Dictyostelium discoideum
#=GS Q54YD9/311-466_500-652  DE Folic acid synthesis protein FOL1
#=GS Q54YD9/311-466_500-652  DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; 
#=GS Q54YD9/311-466_500-652  DR EC; 2.5.1.15; 2.7.6.3; 4.1.2.25; 
#=GS O84619/174-448          AC O84619
#=GS O84619/174-448          OS Chlamydia trachomatis D/UW-3/CX
#=GS O84619/174-448          DE Folate synthesis bifunctional protein
#=GS O84619/174-448          DR ORG; Bacteria; Chlamydiae; Chlamydiia; Chlamydiales; Chlamydiaceae; Chlamydia; Chlamydia trachomatis; 
#=GS O84619/174-448          DR EC; 2.5.1.15; 2.7.6.3; 
#=GS B0R3B1/537-813          AC B0R3B1
#=GS B0R3B1/537-813          OS Halobacterium salinarum R1
#=GS B0R3B1/537-813          DE Folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase
#=GS B0R3B1/537-813          DR ORG; Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; Halobacterium salinarum; 
#=GS B0R3B1/537-813          DR EC; 2.5.1.15; 6.3.2.17; 
#=GS Q0U3R8/1-269            AC Q0U3R8
#=GS Q0U3R8/1-269            OS Parastagonospora nodorum SN15
#=GS Q0U3R8/1-269            DE Uncharacterized protein
#=GS Q0U3R8/1-269            DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae; Parastagonospora; Parastagonospora nodorum; 
#=GS F0ZU41/302-614          AC F0ZU41
#=GS F0ZU41/302-614          OS Dictyostelium purpureum
#=GS F0ZU41/302-614          DE Uncharacterized protein
#=GS F0ZU41/302-614          DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; 
#=GS A0A1T4J1B8/176-448      AC A0A1T4J1B8
#=GS A0A1T4J1B8/176-448      OS Chlamydia suis
#=GS A0A1T4J1B8/176-448      DE 2-amino-4-hydroxy-6-hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase,Dihydropteroate synthase,dihydropteroate synthase,dihydropteroate synthase,Pterin binding enzyme
#=GS A0A1T4J1B8/176-448      DR ORG; Bacteria; Chlamydiae; Chlamydiia; Chlamydiales; Chlamydiaceae; Chlamydia; Chlamydia suis; 
#=GS A0A0E9D8B1/174-448      AC A0A0E9D8B1
#=GS A0A0E9D8B1/174-448      OS Chlamydia trachomatis
#=GS A0A0E9D8B1/174-448      DE 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
#=GS A0A0E9D8B1/174-448      DR ORG; Bacteria; Chlamydiae; Chlamydiia; Chlamydiales; Chlamydiaceae; Chlamydia; Chlamydia trachomatis; 
#=GS A0A0E9D8B1/174-448      DR EC; 2.5.1.15; 2.7.6.3; 
#=GS A0A0H2X2W0/174-448      AC A0A0H2X2W0
#=GS A0A0H2X2W0/174-448      OS Chlamydia trachomatis A/HAR-13
#=GS A0A0H2X2W0/174-448      DE 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
#=GS A0A0H2X2W0/174-448      DR ORG; Bacteria; Chlamydiae; Chlamydiia; Chlamydiales; Chlamydiaceae; Chlamydia; Chlamydia trachomatis; 
#=GS A0A0H2X2W0/174-448      DR EC; 2.5.1.15; 2.7.6.3; 
#=GS G4NMQ8/174-448          AC G4NMQ8
#=GS G4NMQ8/174-448          OS Chlamydia trachomatis A2497
#=GS G4NMQ8/174-448          DE 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
#=GS G4NMQ8/174-448          DR ORG; Bacteria; Chlamydiae; Chlamydiia; Chlamydiales; Chlamydiaceae; Chlamydia; Chlamydia trachomatis; 
#=GS G4NMQ8/174-448          DR EC; 2.5.1.15; 2.7.6.3; 
#=GS Q9HS44/537-813          AC Q9HS44
#=GS Q9HS44/537-813          OS Halobacterium salinarum NRC-1
#=GS Q9HS44/537-813          DE Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase
#=GS Q9HS44/537-813          DR ORG; Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; Halobacterium salinarum; 
#=GS Q9HS44/537-813          DR EC; 2.5.1.15; 6.3.2.17; 
#=GF SQ 10
Q54YD9/311-466_500-652          TCNNIIEKVIRIGNLNYNW-NDKTFIMGILNVTPDSFVDGGKFNTLEKSIQQATAL--IEQGADIIDIGGQSTYPGAQQI-SIEEEINRVVPTIKKIREVLG-----NDIPLSIDTLHHQVAKEAILA-GCNIINDVSG------------EFRVPIILNHSQPTTQYLQQKQNEQYLNNNNNNNNNNDDNDNDNR-SKIKQKIDLSSPKIETCTKLGL-FRWQIILDPGLGFYKTYEQSIEILQRGKELMG----LGFPVLIGPSRKGFIANTIANAEKDKSLPPPSPKSERRLWGTIACCCIGSMWGANIIRIHDIPEIRDAMLISDSVNKPQRR
O84619/174-448                  G----------------SF-GSATQIMGIVNITDNSISDTGLFLEARRAAAHAERL--FAEGASIIDLGAQATNPRVKDLGSVEQEWERLEPVLRLLAERWGAAQQCPD--VSIDTFRPEIIRRAVEVFPIRWINDVSGG--SLEMAHLAKEFGLRLLINHSCSLPP--------------------RPDCVLSYEESPIEQMLRWGESQLEQFAQVGLDTSWQVVFDPGIGFGKTPVQSMLLMDGVKQFKR---VLECPVLIGHSRKSCLSMLGRF------------NSNDRDWETIGCSVSLHDRGVDYLRVHQVEGNRRAL--AAAAWAGM--
B0R3B1/537-813                  -----IQAA--PATHGYPWEGERTAVMGILNVTPDSFHDGGEYDALEDAVARAESM--AENGVDVIDIGGESTRPGADAV-SVADELDRVLPVIERISDL--------DVLLSVDTRKAEVARQALEA-GADILNDVTG-LDDPEMRFVAAEYDAPIVVMHSIDAPV--------------------DPDSDPDYD-DVVDDVIAELTERVLLAEKAGV-PRERIIVDPGLGFGKSAAEGFELLDRADEFHA----LGGPVLVGHSHKSMFGAVDRYPD-------------EGGYATAAASALAADRGADIVRVHDVPENVAAVRVAEATRTGAD-
Q0U3R8/1-269                    --------------------------MSILNVTPDSFSDGGKNYNLDPDSLHRTILSHVSAGATIIDIGGQSTRPGSPQA-SSSEELQRVLPAINLIRSLNL-----PNIPISIDTYRADVAEAAINA-GAHIINDVSAGQMDPAMLPTAAKLGCTVCLMHMRGTPE--------------------TMNFLTDYPAGLLETIGAELLARVHDAEAAGI-RRWRIILDPGIGFAKTLDQNLELLRRFEELRAYPGLENFPWLVGTSRKAFIGKITGVEE-----------ARERVWGTAASVAAAVQGGADVVRVHDVKEMGQVARMADAIWRV---
F0ZU41/302-614                  S----IQKIFRIGKINWRW-NKKTFIMGILNVTPDSFVDGGKYDSVQKSLDQATKL--ITQGSDIIDIGGQSTYPGAAQI-TIQEEIDRVVPVIKKIREKY------PDIPISIDTYNHQVAKEAILA-GCNLINDVSGAMKDPNMFLIAKEYKTPIILNHQQPTTQYLQQKQNEQNVNANTNQS--SQKIDLSNP-SVITTLNNFFKERIETATKLGL-YRWQLILDPGLGFYKTYEQSIEIIKKGKDLIS----LGFPVLIGPSRKGFIAQTIAKYDESSNGEVPPPNSERRLYGTVACCCIAASWGVNIVRIHDINQIKDSLLISDSIYKNQQ-
A0A1T4J1B8/176-448              ------------------F-GPATQIMGVVNITDNSISDTGLFLEARRAAAHAERL--FAEGASIIDLGAQATNPRVKDLGNVEQEWGRLEPVLQLLAERWKGAKQYPD--VSIDTFRPEIIRRAIEVFPIRWINDVSGG--SLEMAHLAKEFGLRLLINHSCSLPP--------------------RPDCVLSYEESPVTQMLRWGESQLETFAQIGLDTSWQVVFDPGISFGKTPVQSMLLMEGVEQFKR---VLECPVLIGHSRKSCLSLLGRF------------SYQDRDWETIGCSVALHDRGVDYLRVHQVEGNRRAL--AAAAWAGM--
A0A0E9D8B1/174-448              G----------------SF-GSATQIMGIVNITDNSISDTGLFLEARRAAAHAERL--FAEGASIIDLGAQATNPRVKDLGSVEQEWERLEPVLRLLAERWGAAQQCPD--VSIDTFRPEIIRRAVEVFPIRWINDVSGG--SLEMAHLAKEFGLRLLINHSCSLPP--------------------RPDCVLSYEESPIEQMLRWGESQLEQFAQVGLDTSWQVVFDPGIGFGKTPVQSMLLMDGVKQFKR---VLECPVLIGHSRKSCLSMLGRF------------NSNDRDWETIGCSVSLHDRGVDYLRVHQVEGNRRAL--AAAAWAGM--
A0A0H2X2W0/174-448              G----------------SF-GSATQIMGIVNITDNSISDTGLFLEARRAAAHAERL--FAEGASIIDLGAQATNPRVKDLGSVEQEWERLEPVLRLLAERWGAAQQCPD--VSIDTFRPEIIRRAVEVFPIRWINDVSGG--SLEMAHLAKEFGLRLLINHSCSLPP--------------------RPDCVLSYEESPIEQMLRWGESQLEQFAQVGLDTSWQVVFDPGIGFGKTPVQSMLLMDGVKQFKR---VLECPVLIGHSRKSCLSMLGRF------------NSNDRDWETIGCSVSLHDRGVDYLRVHQVEGNRRAL--AAAAWAGM--
G4NMQ8/174-448                  G----------------SF-GSATQIMGIVNITDNSISDTGLFLEARRAAAHAERL--FAEGASIIDLGAQATNPRVKDLGSVEQEWERLEPVLRLLAERWGAAQQCPD--VSIDTFRPEIIRRAVEVFPIRWINDVSGG--SLEMAHLAKEFGLRLLINHSCSLPP--------------------RPDCVLSYEESPIEQMLRWGESQLEQFAQVGLDTSWQVVFDPGIGFGKTPVQSMLLMDGVKQFKR---VLECPVLIGHSRKSCLSMLGRF------------NSNDRDWETIGCSVSLHDRGVDYLRVHQVEGNRRAL--AAAAWAGM--
Q9HS44/537-813                  -----IQAA--PATHGYPWEGERTAVMGILNVTPDSFHDGGEYDALEDAVARAESM--AENGVDVIDIGGESTRPGADAV-SVADELDRVLPVIERISDL--------DVLLSVDTRKAEVARQALEA-GADILNDVTG-LDDPEMRFVAAEYDAPIVVMHSIDAPV--------------------DPDSDPDYD-DVVDDVIAELTERVLLAEKAGV-PRERIIVDPGLGFGKSAAEGFELLDRADEFHA----LGGPVLVGHSHKSMFGAVDRYPD-------------EGGYATAAASALAADRGADIVRVHDVPENVAAVRVAEATRTGAD-
#=GC scorecons                  1000011000001000123042362597869795695495935334445445753700444954799696769495534416645934963966446463210101047215979945467564954615444799967200444623364764345455953446300000000000000000000346344564153644434233455434454961355667599968949633754466453556340001653969795979545534353020000000000232563549565543434595645979573544365116464444200
#=GC scorecons_70               _______________________*__*******_**__*_*___________*__*_____*__*****_*_*_*______*___*__**_***__*___________*___****____*___*________******______*___*_**_______*____*_______________________*_________*_________________**____***_******_**__*___*______*______*__*****_***_________________________*___*__________*_*__***_*_____*___*_*_______
#=GC scorecons_80               __________________________***_*_*__*__*_*___________*__*_____*__***_*___*_*__________*__*__*________________*___****________*_________***_*____________*________*________________________________________________________*_________***_**_*________________________*_*_*_*_*_____________________________*__________*____***_*___________________
#=GC scorecons_90               __________________________*_*_*_*__*__*_*____________________*___**_*___*_*__________*__*__*____________________*_**________*_________***_______________________*________________________________________________________*_________***__*_*________________________*_*_*_*_*_____________________________*__________*____*_*_____________________
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