# STOCKHOLM 1.0 #=GF ID 2.60.40.2300/FF/000003 #=GF DE Neutral ceramidase #=GF AC 2.60.40.2300/FF/000003 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 72.019 #=GS Q9VA70/572-704 AC Q9VA70 #=GS Q9VA70/572-704 OS Drosophila melanogaster #=GS Q9VA70/572-704 DE Neutral ceramidase #=GS Q9VA70/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9VA70/572-704 DR GO; GO:0005576; GO:0005737; GO:0006665; GO:0007268; GO:0016079; GO:0017040; GO:0031629; GO:0035187; GO:0045494; GO:0046514; #=GS Q9VA70/572-704 DR EC; 3.5.1.23; #=GS A4V3N7/572-704 AC A4V3N7 #=GS A4V3N7/572-704 OS Drosophila melanogaster #=GS A4V3N7/572-704 DE Ceramidase, isoform B #=GS A4V3N7/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS A4V3N7/572-704 DR EC; 3.5.1.23; #=GS D6X3Y4/565-696 AC D6X3Y4 #=GS D6X3Y4/565-696 OS Tribolium castaneum #=GS D6X3Y4/565-696 DE Neutral ceramidase-like Protein #=GS D6X3Y4/565-696 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS Q7QG18/570-720 AC Q7QG18 #=GS Q7QG18/570-720 OS Anopheles gambiae #=GS Q7QG18/570-720 DE AGAP003730-PA #=GS Q7QG18/570-720 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS Q5TXH8/68-218 AC Q5TXH8 #=GS Q5TXH8/68-218 OS Anopheles gambiae #=GS Q5TXH8/68-218 DE AGAP012841-PA #=GS Q5TXH8/68-218 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS Q7QI06/579-709 AC Q7QI06 #=GS Q7QI06/579-709 OS Anopheles gambiae #=GS Q7QI06/579-709 DE AGAP000973-PA #=GS Q7QI06/579-709 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS B4LYM3/571-703 AC B4LYM3 #=GS B4LYM3/571-703 OS Drosophila virilis #=GS B4LYM3/571-703 DE Uncharacterized protein, isoform A #=GS B4LYM3/571-703 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GS A0A182LAZ3/605-753 AC A0A182LAZ3 #=GS A0A182LAZ3/605-753 OS Anopheles coluzzii #=GS A0A182LAZ3/605-753 DE Uncharacterized protein #=GS A0A182LAZ3/605-753 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles coluzzii; #=GS A0A0R3NKD0/572-704 AC A0A0R3NKD0 #=GS A0A0R3NKD0/572-704 OS Drosophila pseudoobscura pseudoobscura #=GS A0A0R3NKD0/572-704 DE Uncharacterized protein, isoform B #=GS A0A0R3NKD0/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; #=GS A0A0R3NKD0/572-704 DR EC; 3.5.1.23; #=GS Q29C43/572-704 AC Q29C43 #=GS Q29C43/572-704 OS Drosophila pseudoobscura pseudoobscura #=GS Q29C43/572-704 DE Neutral ceramidase #=GS Q29C43/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; #=GS Q29C43/572-704 DR EC; 3.5.1.23; #=GS B4R1M6/572-704 AC B4R1M6 #=GS B4R1M6/572-704 OS Drosophila simulans #=GS B4R1M6/572-704 DE GD21520 #=GS B4R1M6/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS A0A3B0K988/622-754 AC A0A3B0K988 #=GS A0A3B0K988/622-754 OS Drosophila guanche #=GS A0A3B0K988/622-754 DE Blast:Neutral ceramidase #=GS A0A3B0K988/622-754 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; #=GS B4NGW1/571-703 AC B4NGW1 #=GS B4NGW1/571-703 OS Drosophila willistoni #=GS B4NGW1/571-703 DE Uncharacterized protein #=GS B4NGW1/571-703 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; #=GS A0A3B0K2B9/572-704 AC A0A3B0K2B9 #=GS A0A3B0K2B9/572-704 OS Drosophila guanche #=GS A0A3B0K2B9/572-704 DE Blast:Neutral ceramidase #=GS A0A3B0K2B9/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; #=GS A0A3B0JCJ4/647-779 AC A0A3B0JCJ4 #=GS A0A3B0JCJ4/647-779 OS Drosophila guanche #=GS A0A3B0JCJ4/647-779 DE Blast:Neutral ceramidase #=GS A0A3B0JCJ4/647-779 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; #=GS B4HZR3/572-704 AC B4HZR3 #=GS B4HZR3/572-704 OS Drosophila sechellia #=GS B4HZR3/572-704 DE GM12881 #=GS B4HZR3/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS B4GNM1/498-630 AC B4GNM1 #=GS B4GNM1/498-630 OS Drosophila persimilis #=GS B4GNM1/498-630 DE GL13459 #=GS B4GNM1/498-630 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila persimilis; #=GS B3MTB9/574-706 AC B3MTB9 #=GS B3MTB9/574-706 OS Drosophila ananassae #=GS B3MTB9/574-706 DE Uncharacterized protein, isoform A #=GS B3MTB9/574-706 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; Drosophila ananassae; #=GS A0A1W4VRB3/575-707 AC A0A1W4VRB3 #=GS A0A1W4VRB3/575-707 OS Drosophila ficusphila #=GS A0A1W4VRB3/575-707 DE neutral ceramidase #=GS A0A1W4VRB3/575-707 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS B3P584/572-704 AC B3P584 #=GS B3P584/572-704 OS Drosophila erecta #=GS B3P584/572-704 DE GG11751 #=GS B3P584/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B4PLW9/572-704 AC B4PLW9 #=GS B4PLW9/572-704 OS Drosophila yakuba #=GS B4PLW9/572-704 DE CDase, isoform A #=GS B4PLW9/572-704 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS Q6XIC0/21-153 AC Q6XIC0 #=GS Q6XIC0/21-153 OS Drosophila yakuba #=GS Q6XIC0/21-153 DE Similar to Drosophila melanogaster CG1471 #=GS Q6XIC0/21-153 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS A0A182LIT5/522-652 AC A0A182LIT5 #=GS A0A182LIT5/522-652 OS Anopheles coluzzii #=GS A0A182LIT5/522-652 DE Uncharacterized protein #=GS A0A182LIT5/522-652 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles coluzzii; #=GF SQ 23 Q9VA70/572-704 GVLFDGHPINTDFGYVKSQPNKE-YGINETVKVTYISGNPRNNLFTEKTYFTIERKINE-------------------DRWKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPYEGLTHSFTVKED A4V3N7/572-704 GVLFDGHPINTDFGYVKSQPNKE-YGINETVKVTYISGNPRNNLFTEKTYFTIERKINE-------------------DRWKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPYEGLTHSFTVKED D6X3Y4/565-696 RVMFDTPGLMHHFGDCLLQPPKS-ARVGSKVRAKFVSGHPRNNLMTEKTFLTVEKLADN-------------------GKWIVLATDADWETKFTWTRTSTLIGGSEATIEWEIPSDATPGLYRIHHFGHFQHIFGGVHPYSGATDTFQVTK- Q7QG18/570-720 GVVFDGHPFGWYFGDCKVQPRETPYRRGDTVRVMFIAGNPRNNLMHERTFFTVERLRPEFEETNSVDAHQQGGGGGGRDVWEVVATDANWETKFKWHRRSTLFAYSDIELEWEVPEQVDPGTYRIQHFGYWRYILGGIFPYNGTTRNFTVE-- Q5TXH8/68-218 GVVFDGHPFGWYFGDCKVQPRETPYRRGDTVRVMFIAGNPRNNLMHERTFFTVERLRPEFEETNSVDAHQQGGGGGGRDVWEVVATDANWETKFKWHRRSTLFAYSDIELEWEVPEQVDPGTYRIQHFGYWRYILGGIFPYNGTTRNFTVE-- Q7QI06/579-709 GVIFDSHPLGKEFGDVKVHPEAA-YERGATVSAVFIAGNPRNNLMHDKSFFTVEQQQPD-------------------GNWSVVATDANWETRFRWERTSTILGFSDIEFSWTIGPNTLDGLYRIRHFGYYRYILGGVYPYVGATNAFSVK-- B4LYM3/571-703 GVLFDGHPIGTDFGYVKTQPNKQ-YGINDTVRVTYISGNPRNNLFTEKTYFTVERKITE-------------------DRWKVAYTDASWETKMIWHRTNTILGFSELEIYWNISPQTLPGEYRIRHSGEYKYILGGKYPYEGLTHSFTVTED A0A182LAZ3/605-753 GVVFDGHPFGWYFGDCKVQPRETPYRRGDTVRVMFIAGNPRNNLMHERTYFTVERLRPEFEETNSVDAHQQ--GGGGRDVWEVVATDANWETKFKWHRRSTLFAYSDIELEWEVPEQVDPGTYRIQHFGYWRYILGGIFPYNGTTRNFTVE-- A0A0R3NKD0/572-704 GVLFDGHPINTDFGYVKTQPEKE-YGINDTVKVTYISGNPRNNLFTEKTYFTVERKINE-------------------DRWKVAYTDASWETKMIWHRTNTILGFSDLEIYWNISPQTLPGVYRIRHSGEYKYILGGKYPYEGLSHSFTVKED Q29C43/572-704 GVLFDGHPINTDFGYVKTQPEKE-YGINDTVKVTYISGNPRNNLFTEKTYFTVERKINE-------------------DRWKVAYTDASWETKMIWHRTNTILGFSDLEIYWNISPQTLPGVYRIRHSGEYKYILGGKYPYEGLSHSFTVKED B4R1M6/572-704 GVLFDGHPINTDFGYVKSQPNKE-YGINETVKVTYISGNPRNNLFTEKTYFTIERKINE-------------------DRWKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPYEGLTHSFTVKED A0A3B0K988/622-754 GVLFDGHPINTDFGYVKTQPNKE-YGINDTVKVTYISGNPRNNLFTEKTYFTVERKINE-------------------DRWKVAYTDASWETKMIWHRTNTILGFSELEIYWNISPQTLPGVYRIRHSGEYKYILGGKYPYEGLSHSFTVNED B4NGW1/571-703 GVLFDGHPIGTDFGYVKTQPNKE-YGINETVHVSYISGNPRNNLFTEKTYFTIERKINE-------------------DRWKVTYTDASWETKMIWHRTNIILGFSEVSIYWNISPQTLPGEYRIRHSGEYKYILGGKYPYEGLTQSFIVKED A0A3B0K2B9/572-704 GVLFDGHPINTDFGYVKTQPNKE-YGINDTVKVTYISGNPRNNLFTEKTYFTVERKINE-------------------DRWKVAYTDASWETKMIWHRTNTILGFSELEIYWNISPQTLPGVYRIRHSGEYKYILGGKYPYEGLSHSFTVNED A0A3B0JCJ4/647-779 GVLFDGHPINTDFGYVKTQPNKE-YGINDTVKVTYISGNPRNNLFTEKTYFTVERKINE-------------------DRWKVAYTDASWETKMIWHRTNTILGFSELEIYWNISPQTLPGVYRIRHSGEYKYILGGKYPYEGLSHSFTVNED B4HZR3/572-704 GVLFDGHPINTDFGYVKSQPNKE-YGINETVKVTYISGNPRNNLFTEKTYFTIERKINE-------------------DRWKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPYEGLTHSFTVKED B4GNM1/498-630 GVLFDGHPINTDFGYVKTQPEKE-YGINDTVKVTYISGNPRNNLFTEKTYFTVERKINE-------------------DRWKVAYTDASWETKMIWHRTNTILGFSDLEIYWNISPQTLPGVYRIRHSGEYKYILGGKYPYEGLSHSFTVKED B3MTB9/574-706 GVLFDGHPINTDFGYVKTQPNKE-YGINETVKVSYISGNPRNNLFTEKTYFTVERKINE-------------------DRWKVAYTDASWETRMIWHRTNTILGFSELDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPYEGLSHSFTVKED A0A1W4VRB3/575-707 GVLFDGHPINTDFGYVKSQPNKE-YGINETVKVTYISGNPRNNLFTEKTYFTVERKINE-------------------DRWKVAYTDASWETKMIWHRTNTILGFSELDIYWTISPQTLPGEYRIRHSGVYKYILGGKYPYEGLTHSFTVKED B3P584/572-704 GVLFDGHPINTDFGYVKAQPNKE-YGINETVKVTYISGNPRNNLFTEKTYFTIERKINE-------------------DRWKVAYTDASWETKMVWHRTNTILGFSELDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPYEGLTHSFAVKED B4PLW9/572-704 GVLFDGHPINTDFGYVKSQPNKV-YGINETVKVTYISGNPRNNLFTEKTYFTIERKINE-------------------DRWKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPYEGLTHSFTVKED Q6XIC0/21-153 GVLFDGHPINTDFGYVKSQPNKV-YGINETVKVTYISGNPRNNLFTEKTYFTIERKINE-------------------DRWKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYKYILSGKYPYEGLTHSFTVKED A0A182LIT5/522-652 GVIFDSHPLGKEFGDVKVHPEAA-YERGATVSAVFIAGNPRNNLMHDKSFFTVEQQQPD-------------------GNWSVVATDANWETRFRWERTSTILGFSDIEFSWTIGPNTLDGLYRIRHFGYYRYILGGVYPYVGATNAFSVK-- #=GC scorecons 795996775534995574794540754557956478698999995587778979744470000000000000000000649495499959997539696686666975654947556547939996959466898894799494755969522 #=GC scorecons_70 **_*****____**__*_**____*____**_*_**_*******__*********___*___________________*_*_*__***_****__***__*******____*_*__*__**_*****_*__******_***_*_*__*_*___ #=GC scorecons_80 **_**_**____**__*_**____*____**___**_*******__*********___*_____________________*_*__***_****__*_*__*____*_____*_*______*_***_*_*___*****__**_*____*_*___ #=GC scorecons_90 _*_**_______**_____*__________*____*_*_*****______**_*__________________________*_*__***_***___*_*__*____*_____*________*_***_*_*___*****__**_*____*_*___ //