# STOCKHOLM 1.0 #=GF ID 2.60.120.200/FF/000204 #=GF DE Crumbs cell polarity complex component 2 #=GF AC 2.60.120.200/FF/000204 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 76.520 #=GS Q80YA8/442-603 AC Q80YA8 #=GS Q80YA8/442-603 OS Mus musculus #=GS Q80YA8/442-603 DE Protein crumbs homolog 2 #=GS Q80YA8/442-603 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS Q80YA8/442-603 DR GO; GO:0001707; GO:0001756; GO:0005515; GO:0010470; GO:0010718; GO:0010951; GO:0014028; GO:0016324; GO:0019828; GO:0030513; GO:0032991; GO:0044877; GO:0045199; GO:0055111; GO:0072358; #=GS Q5IJ48/450-593 AC Q5IJ48 #=GS Q5IJ48/450-593 OS Homo sapiens #=GS Q5IJ48/450-593 DE Protein crumbs homolog 2 #=GS Q5IJ48/450-593 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS Q5IJ48/450-593 DR GO; GO:0001707; GO:0001756; GO:0010470; GO:0010718; GO:0010951; GO:0014028; GO:0016324; GO:0019828; GO:0030513; GO:0032991; GO:0044877; GO:0045199; GO:0055111; GO:0070062; GO:0072358; #=GS D4A3W2/437-602 AC D4A3W2 #=GS D4A3W2/437-602 OS Rattus norvegicus #=GS D4A3W2/437-602 DE Crumbs cell polarity complex component 2 #=GS D4A3W2/437-602 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Rattus; Rattus norvegicus; #=GS D4A3W2/437-602 DR GO; GO:0001707; GO:0001756; GO:0010718; GO:0014028; GO:0030513; GO:0045199; GO:0072358; #=GS F1N2V0/442-596 AC F1N2V0 #=GS F1N2V0/442-596 OS Bos taurus #=GS F1N2V0/442-596 DE Crumbs 2, cell polarity complex component #=GS F1N2V0/442-596 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS F1N2V0/442-596 DR GO; GO:0001707; GO:0001756; GO:0010718; GO:0014028; GO:0030513; GO:0045199; GO:0072358; #=GS F6X3Y3/541-705 AC F6X3Y3 #=GS F6X3Y3/541-705 OS Monodelphis domestica #=GS F6X3Y3/541-705 DE Uncharacterized protein #=GS F6X3Y3/541-705 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Didelphimorphia; Didelphidae; Didelphinae; Monodelphis; Monodelphis domestica; #=GS F1SKU3/456-598 AC F1SKU3 #=GS F1SKU3/456-598 OS Sus scrofa #=GS F1SKU3/456-598 DE Uncharacterized protein #=GS F1SKU3/456-598 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Suina; Suidae; Sus; Sus scrofa; #=GS F1SKU3/456-598 DR GO; GO:0001707; GO:0001756; GO:0010718; GO:0014028; GO:0030513; GO:0045199; GO:0072358; #=GS A0A337SRL8/451-600 AC A0A337SRL8 #=GS A0A337SRL8/451-600 OS Felis catus #=GS A0A337SRL8/451-600 DE Uncharacterized protein #=GS A0A337SRL8/451-600 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis; Felis catus; #=GS I3NFS4/455-604 AC I3NFS4 #=GS I3NFS4/455-604 OS Ictidomys tridecemlineatus #=GS I3NFS4/455-604 DE Uncharacterized protein #=GS I3NFS4/455-604 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys; Ictidomys tridecemlineatus; #=GS I3NFS4/455-604 DR GO; GO:0001707; GO:0001756; GO:0010718; GO:0014028; GO:0030513; GO:0045199; GO:0072358; #=GS H0XLX5/440-603 AC H0XLX5 #=GS H0XLX5/440-603 OS Otolemur garnettii #=GS H0XLX5/440-603 DE Uncharacterized protein #=GS H0XLX5/440-603 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur; Otolemur garnettii; #=GS H0XLX5/440-603 DR GO; GO:0001707; GO:0001756; GO:0010718; GO:0014028; GO:0030513; GO:0045199; GO:0072358; #=GS A0A452G745/431-584 AC A0A452G745 #=GS A0A452G745/431-584 OS Capra hircus #=GS A0A452G745/431-584 DE Uncharacterized protein #=GS A0A452G745/431-584 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Capra; Capra hircus; #=GS F7HE09/457-598 AC F7HE09 #=GS F7HE09/457-598 OS Macaca mulatta #=GS F7HE09/457-598 DE Uncharacterized protein #=GS F7HE09/457-598 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta; #=GS F7HE09/457-598 DR GO; GO:0001707; GO:0001756; GO:0010718; GO:0014028; GO:0030513; GO:0045199; GO:0072358; #=GS W5PWM1/408-562 AC W5PWM1 #=GS W5PWM1/408-562 OS Ovis aries #=GS W5PWM1/408-562 DE Crumbs cell polarity complex component 2 #=GS W5PWM1/408-562 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Ovis; Ovis aries; #=GS L8IT26/409-563 AC L8IT26 #=GS L8IT26/409-563 OS Bos mutus #=GS L8IT26/409-563 DE Crumbs-like protein 2 #=GS L8IT26/409-563 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos mutus; #=GS H2PU90/449-591 AC H2PU90 #=GS H2PU90/449-591 OS Pongo abelii #=GS H2PU90/449-591 DE Uncharacterized protein #=GS H2PU90/449-591 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Ponginae; Pongo; Pongo abelii; #=GS H2R133/450-593 AC H2R133 #=GS H2R133/450-593 OS Pan troglodytes #=GS H2R133/450-593 DE Crumbs 2, cell polarity complex component #=GS H2R133/450-593 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS H2R133/450-593 DR GO; GO:0001707; GO:0001756; GO:0010718; GO:0014028; GO:0030513; GO:0045199; GO:0072358; #=GS A0A2K5VZD2/519-660 AC A0A2K5VZD2 #=GS A0A2K5VZD2/519-660 OS Macaca fascicularis #=GS A0A2K5VZD2/519-660 DE Uncharacterized protein #=GS A0A2K5VZD2/519-660 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GS A0A2R9ADE8/441-585 AC A0A2R9ADE8 #=GS A0A2R9ADE8/441-585 OS Pan paniscus #=GS A0A2R9ADE8/441-585 DE Uncharacterized protein #=GS A0A2R9ADE8/441-585 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GS A0A452G750/446-599 AC A0A452G750 #=GS A0A452G750/446-599 OS Capra hircus #=GS A0A452G750/446-599 DE Uncharacterized protein #=GS A0A452G750/446-599 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Capra; Capra hircus; #=GS F7HE06/457-598 AC F7HE06 #=GS F7HE06/457-598 OS Macaca mulatta #=GS F7HE06/457-598 DE Uncharacterized protein #=GS F7HE06/457-598 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta; #=GS A0A2K5VZM9/289-430 AC A0A2K5VZM9 #=GS A0A2K5VZM9/289-430 OS Macaca fascicularis #=GS A0A2K5VZM9/289-430 DE Uncharacterized protein #=GS A0A2K5VZM9/289-430 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GS G7NFU1/357-498 AC G7NFU1 #=GS G7NFU1/357-498 OS Macaca mulatta #=GS G7NFU1/357-498 DE Uncharacterized protein #=GS G7NFU1/357-498 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta; #=GS A0A2R9AHB6/441-585 AC A0A2R9AHB6 #=GS A0A2R9AHB6/441-585 OS Pan paniscus #=GS A0A2R9AHB6/441-585 DE Uncharacterized protein #=GS A0A2R9AHB6/441-585 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GS G7PRH1/416-557 AC G7PRH1 #=GS G7PRH1/416-557 OS Macaca fascicularis #=GS G7PRH1/416-557 DE Crumbs-like protein 2 #=GS G7PRH1/416-557 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GS M3W3C9/447-597 AC M3W3C9 #=GS M3W3C9/447-597 OS Felis catus #=GS M3W3C9/447-597 DE Uncharacterized protein #=GS M3W3C9/447-597 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis; Felis catus; #=GF SQ 24 Q80YA8/442-603 --NTTFSVVSGSSVWGLVPAA---ASLGLALRFRTTLLAGTLATLKDTRDSLELVLVGAVLQATLSRHGT-AVLILTLPDLALNDGHWHQVEVTLHLGTLELRLWHEGCPGQLCVASGPVATGPTASVASGPPGSY-SIYLGGGV-----FAGCFQDVRVEGHLLLPEELKGTV------ Q5IJ48/450-593 --------------QASVPAG---GPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYST-TVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPE------------ D4A3W2/437-602 DQNTTFSVVSGSSVWGLVPAG---ASLAFALRFRTTLLAGALATLKDSRDSLELVLVGAMLQATLWRRGT-ADLVLTLPDLALNDGHWHQVEVTLRLGTLELRLWHEGCPGQLCVVSGTVATDPTASVASGSPEPY-SIHLGGRA-----FAGCFQDVRVEGHLLLPEELKGSVLL---- F1N2V0/442-596 ---TTFSMVAGNPLRASVPAG---SSLGLALRFRTTIRVGALATCSDTQGSVELALVEARLQATLWSHGK-NVLVLRLLEPPLNDGHWHRVEVTLRLGVLELRLWHEDCPAHLCVASSPMA---TAAPAPTPAGSR-FTQLGGVA-----FAGCLQDVQVDGHLLLPEDLG--------- F6X3Y3/541-705 -QSTTFSLAIGGSLLVALPAGDGHGQPAVSLRFRTTLPDGLLFSRGDTVESLTLMLSQGTLWTILRSQGT-E-LPLNLNTPSLSDGHWHRAEVVLLQSALELRLWHEACENGPCLKSHPLV----GEVALDSPAFL-TVHVGGGAGTSPSFVGCLEDVRVDGHMLVPQDLADG------- F1SKU3/456-598 ------------------PAG---GPLGLALRFRTTVTSGPLATRSDTQDSLELALVGAMLQATLRSRGN-NVLVLRLLDMALNDGYWHQVEVALRLGVLELRLWHEGCPARLCMASSPVALPPLASQAPMPAGFC-SSQLGGGA-----FAGCLQDVHVDGHLLLPEDLG--------- A0A337SRL8/451-600 --------------RASVPAG---GPPGLALRFRTTLPAGALATRTDTQDSLELALAGGTLQATLWSHGNATVLPLGPLDLALNDGHWHQAEISLRPGVLELRLWHEDCPARLCVASSPVAPAPVASVAPTPTRFC-SVQLGGTA-----FEGCLQDVRVDGHLLLPEDLGKN------- I3NFS4/455-604 --------------WASVPAG---GPLGLALRFCTTLPAGALATRTDTQGSLELALVGATLQVTL-SHGT-HALVLSLPDLTLNDGHWHQVEVALRLGNLELRLWHEGCPSHLCVASGPVVPSPTASVAPRSPGPC-STQLGSSA-----FAGCLQDVYVDGHLLLPEHLSDNVF----- H0XLX5/440-603 ----TFSVVAGSPVQASVPAG---SPLGLALRFRTTLPTGALATRASTQDSLELALVEAILQATLWSHDT-TVLVLRLPDLALNDGQWHQVEVVLHPGTLELRLWHEACPAQLCVASGPVTLAPTALVAPV--GHF-SAQLGGAA-----FAGCLQDVHVDGHLLLPENLSENVLVGCEH A0A452G745/431-584 ---TTFSMVAGNPVRASVPAG---SSLGLALRFRTTIRVGALATCSDTQGSVELALVEARLQATL--HGK-NVLVLRLLEPPLSDGHWHRVEVTLRLGLLELRLWHKGCPARLCVASSPVA---TAAPAPTPAGSR-FTQLGGVA-----FAGCLQDVQVDGHLLLPEDLGE-------- F7HE09/457-598 ------------------PAG---GPLGLALRFRTTLPAGTLATRNDTRESLELALVAATLQATLWSHGT-TVLVLRLPDLGLNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALAPTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPEDL---------- W5PWM1/408-562 ---TTFSMVAGNPVRASVPAG---SSLRLALRFRTTIRVGALATCSDTQGSVELALVEARLQATL--HGK-NVLVLRLLEPPLSDGHWHRVEVTLHLGLLELRLWHEGCPARLCVASGPVA---TAAPAPTPAGSRFFTQLGGVA-----FAGCLQDVQVDGHLLLPEDLGE-------- L8IT26/409-563 ---TTFSMVAGNPVRASVPAG---SSLGLALRFRTTIRVGALATCSDTQGSVELALVEARLQATLWSHGK-NVLVLRLLEPPLNDGHWHRVEVTLRLGVLELRLWHEGCPAHLCVASSPMA---TAAPAPTPAGSR-FTQLGGVA-----FAGCLQDVQVDGHLLLPEDLG--------- H2PU90/449-591 -----------------VPAG---GPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSHGT-TVLVLRLPDLALNDSHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASAAPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPEDL---------- H2R133/450-593 --------------QASVPAG---GPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYST-TVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPE------------ A0A2K5VZD2/519-660 ------------------PAG---GPLGLALRFRTTLPAGTLATRNDTRESLELALVAATLQATLWSHGT-TVLVLRLPDLGLNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALAPTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPEDL---------- A0A2R9ADE8/441-585 -------------IQASVPAG---GPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYST-TVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPE------------ A0A452G750/446-599 ---TTFSMVAGNPVRASVPAG---SSLGLALRFRTTIRVGALATCSDTQGSVELALVEARLQATL--HGK-NVLVLRLLEPPLSDGHWHRVEVTLRLGLLELRLWHKGCPARLCVASSPVA---TAAPAPTPAGSR-FTQLGGVA-----FAGCLQDVQVDGHLLLPEDLGE-------- F7HE06/457-598 ------------------PAG---GPLGLALRFRTTLPAGTLATRNDTRESLELALVAATLQATLWSHGT-TVLVLRLPDLGLNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALAPTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPEDL---------- A0A2K5VZM9/289-430 ------------------PAG---GPLGLALRFRTTLPAGTLATRNDTRESLELALVAATLQATLWSHGT-TVLVLRLPDLGLNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALAPTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPEDL---------- G7NFU1/357-498 ------------------PAG---GPLGLALRFRTTLPAGTLATRNDTRESLELALVAATLQATLWSHGT-TVLVLRLPDLGLNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALAPTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPEDL---------- A0A2R9AHB6/441-585 -------------IQASVPAG---GPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYST-TVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPE------------ G7PRH1/416-557 ------------------PAG---GPLGLALRFRTTLPAGTLATRNDTRESLELALVAATLQATLWSHGT-TVLVLRLPDLGLNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALAPTASATPLPAGIS-SAQLGDAT-----FAGCLQDVRVDGHLLLPEDL---------- M3W3C9/447-597 -------------VRASVPAG---GPPGLALRFRTTLPAGALATRTDTQDSLELALAGGTLQATLWSHGNATVLPLGPLDLALNDGHWHQAEISLRPGVLELRLWHEDCPARLCVASSPVAPAPVASVAPTPTRFC-SVQLGGTA-----FEGCLQDVRVDGHLLLPEDLGKN------- #=GC scorecons 000111111111122334998000557778999899655959785488559779697474977894567505696957566497988996798595654999999986976589779587722368546736563305478964600000979988996989989898562100000000 #=GC scorecons_70 __________________***_____***********__*_***__**__*******_*_*****__**___****_*_*__***********_*_*__************_*****_***____*__**_*_*_____***__*_____********_*********_*__________ #=GC scorecons_80 __________________***_____*_********___*_***__**__****_*__*_*****___*____*_*_*____*_*****_***_*____********_**__*****_***____*_____________***________*_******_*********____________ #=GC scorecons_90 __________________***________*******___*_*_*__**__*__*_*____*__**________*_*______*_*****__**_*____*******__*____*__*_*______*______________**________*_**_***_*********____________ //