# STOCKHOLM 1.0
#=GF ID 2.30.29.30/FF/000441
#=GF DE Insulin receptor substrate 1
#=GF AC 2.30.29.30/FF/000441
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 82.387
#=GS Q9XTN2/4-107       AC Q9XTN2
#=GS Q9XTN2/4-107       OS Drosophila melanogaster
#=GS Q9XTN2/4-107       DE Insulin receptor substrate 1
#=GS Q9XTN2/4-107       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; 
#=GS Q9XTN2/4-107       DR GO; GO:0005158; GO:0005159; GO:0005515; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0005938; GO:0006629; GO:0007285; GO:0007295; GO:0007296; GO:0007568; GO:0008284; GO:0008286; GO:0008340; GO:0008355; GO:0009267; GO:0010259; GO:0010897; GO:0014068; GO:0034059; GO:0035159; GO:0035264; GO:0040018; GO:0042169; GO:0042593; GO:0042594; GO:0043231; GO:0043491; GO:0043548; GO:0045793; GO:0046620; GO:0046622; GO:0046854; GO:0048009; GO:0048133; GO:0050778; GO:0060250; GO:0060291; GO:0061964; 
#=GS B3MPN6/3-107       AC B3MPN6
#=GS B3MPN6/3-107       OS Drosophila ananassae
#=GS B3MPN6/3-107       DE Insulin receptor substrate 1
#=GS B3MPN6/3-107       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; Drosophila ananassae; 
#=GS B3MPN6/3-107       DR GO; GO:0005158; GO:0005159; GO:0005634; GO:0005737; GO:0007296; GO:0008286; GO:0010259; GO:0043231; GO:0048009; 
#=GS M9PCQ8/4-107       AC M9PCQ8
#=GS M9PCQ8/4-107       OS Drosophila melanogaster
#=GS M9PCQ8/4-107       DE Chico, isoform B
#=GS M9PCQ8/4-107       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; 
#=GS A0A139WDD0/2-107   AC A0A139WDD0
#=GS A0A139WDD0/2-107   OS Tribolium castaneum
#=GS A0A139WDD0/2-107   DE Uncharacterized protein
#=GS A0A139WDD0/2-107   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; 
#=GS H2XZQ9/7-108       AC H2XZQ9
#=GS H2XZQ9/7-108       OS Ciona intestinalis
#=GS H2XZQ9/7-108       DE Uncharacterized protein
#=GS H2XZQ9/7-108       DR ORG; Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; Phlebobranchia; Cionidae; Ciona; Ciona intestinalis; 
#=GS C3ZZ54/5-128       AC C3ZZ54
#=GS C3ZZ54/5-128       OS Branchiostoma floridae
#=GS C3ZZ54/5-128       DE Uncharacterized protein
#=GS C3ZZ54/5-128       DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; 
#=GS B4HWI2/4-107       AC B4HWI2
#=GS B4HWI2/4-107       OS Drosophila sechellia
#=GS B4HWI2/4-107       DE Insulin receptor substrate 1
#=GS B4HWI2/4-107       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; 
#=GS B4HWI2/4-107       DR GO; GO:0005158; GO:0005159; GO:0005634; GO:0005737; GO:0007296; GO:0008286; GO:0010259; GO:0043231; GO:0048009; 
#=GS B4NZ70/4-107       AC B4NZ70
#=GS B4NZ70/4-107       OS Drosophila yakuba
#=GS B4NZ70/4-107       DE Insulin receptor substrate 1
#=GS B4NZ70/4-107       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; 
#=GS B4NZ70/4-107       DR GO; GO:0005158; GO:0005159; GO:0005634; GO:0005737; GO:0007296; GO:0008286; GO:0010259; GO:0043231; GO:0048009; 
#=GS B3N946/4-107       AC B3N946
#=GS B3N946/4-107       OS Drosophila erecta
#=GS B3N946/4-107       DE Insulin receptor substrate 1
#=GS B3N946/4-107       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; 
#=GS B3N946/4-107       DR GO; GO:0005158; GO:0005159; GO:0005634; GO:0005737; GO:0007296; GO:0008286; GO:0010259; GO:0043231; GO:0048009; 
#=GS A0A0R1DL60/24-128  AC A0A0R1DL60
#=GS A0A0R1DL60/24-128  OS Drosophila yakuba
#=GS A0A0R1DL60/24-128  DE Uncharacterized protein, isoform D
#=GS A0A0R1DL60/24-128  DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; 
#=GS A0A0R1DQJ3/4-107   AC A0A0R1DQJ3
#=GS A0A0R1DQJ3/4-107   OS Drosophila yakuba
#=GS A0A0R1DQJ3/4-107   DE Uncharacterized protein, isoform B
#=GS A0A0R1DQJ3/4-107   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; 
#=GS A0A1W4UUR3/3-107   AC A0A1W4UUR3
#=GS A0A1W4UUR3/3-107   OS Drosophila ficusphila
#=GS A0A1W4UUR3/3-107   DE insulin receptor substrate 1
#=GS A0A1W4UUR3/3-107   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; 
#=GS A0A0J9TKB9/4-107   AC A0A0J9TKB9
#=GS A0A0J9TKB9/4-107   OS Drosophila simulans
#=GS A0A0J9TKB9/4-107   DE Uncharacterized protein, isoform A
#=GS A0A0J9TKB9/4-107   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; 
#=GS A0A0Q5WA87/4-107   AC A0A0Q5WA87
#=GS A0A0Q5WA87/4-107   OS Drosophila erecta
#=GS A0A0Q5WA87/4-107   DE Uncharacterized protein, isoform B
#=GS A0A0Q5WA87/4-107   DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; 
#=GS A0A0J9R0R6/72-176  AC A0A0J9R0R6
#=GS A0A0J9R0R6/72-176  OS Drosophila simulans
#=GS A0A0J9R0R6/72-176  DE Uncharacterized protein, isoform B
#=GS A0A0J9R0R6/72-176  DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; 
#=GS B4Q8R5/4-107       AC B4Q8R5
#=GS B4Q8R5/4-107       OS Drosophila simulans
#=GS B4Q8R5/4-107       DE GD22290
#=GS B4Q8R5/4-107       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; 
#=GS A0A1W2WBJ6/7-108   AC A0A1W2WBJ6
#=GS A0A1W2WBJ6/7-108   OS Ciona intestinalis
#=GS A0A1W2WBJ6/7-108   DE insulin receptor substrate 1-like
#=GS A0A1W2WBJ6/7-108   DR ORG; Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; Phlebobranchia; Cionidae; Ciona; Ciona intestinalis; 
#=GS C3ZU02/220-326     AC C3ZU02
#=GS C3ZU02/220-326     OS Branchiostoma floridae
#=GS C3ZU02/220-326     DE Uncharacterized protein
#=GS C3ZU02/220-326     DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; 
#=GF SQ 18
Q9XTN2/4-107               --ISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSTSAARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
B3MPN6/3-107               -SISDDGMVLSGYHKKLK-----------------TMKKKFFVLYEETSINQARLEYYDTEKKFLQRAEPKRVIYLKDCFNINRRLDTKHRFVIVLSSREGGFGIVLESENDLRKWLDKLLLL-
M9PCQ8/4-107               --ISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSTSAARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
A0A139WDD0/2-107           -SGSEGGVVRSGYLKKLK-----------------TSRKKFFVLRAETADASARLEYYDSERKFNNGLPPKRSIPLKNCFNINKRLDTKHKHVIALYTKDDCFCVVLDNDDDLDSWLKALLKLQ
H2XZQ9/7-108               YSAMSTDIVLKGTLRKAK-----------------TWNKRFFVLRD---GNPPKLEYYENERKWKVN-KPKRQISLGNPWNIDKKKDTKHEFLIVIFTKDEYFTMAAESADVQQTWISALLKT-
C3ZZ54/5-128               GGDTPEDVRKHGYLRKLKVGPTGQGASLPEGRGGWTMKKRYFVLHAKSSAGAARLEYFDNEKKWRHGAAPKRTIFLHHCFNINKKDDGKHKHMIVLYTRDECFSLVADTADEHDTWLAVLKDLH
B4HWI2/4-107               --ISDDGMALSGNLKKLK-----------------TMKKKFFVLYEETSTSSARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
B4NZ70/4-107               --ISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSHSAARLEYYDSEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
B3N946/4-107               --ISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSNSSARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKQRFVIVLSSRDGGFGIVLESENDLRKWLDKLLVL-
A0A0R1DL60/24-128          -SISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSHSAARLEYYDSEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
A0A0R1DQJ3/4-107           --ISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSHSAARLEYYDSEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
A0A1W4UUR3/3-107           -SISDDGMVLSGYHKKLK-----------------TMKKKFFALYEETCNSSARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRMDTKHRFVIVLSSREGGFGIVLENENDLRKWLDKLLFL-
A0A0J9TKB9/4-107           --ISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSTSSARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
A0A0Q5WA87/4-107           --ISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSNSSARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKQRFVIVLSSRDGGFGIVLESENDLRKWLDKLLVL-
A0A0J9R0R6/72-176          -SISDDGMALSGYLKKLK-----------------TMKKKFFVLYEETSTSSARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
B4Q8R5/4-107               --ISDDGMALSGYLKKLK-----------------TMKKKFFLLYEETSTSSARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVL-
A0A1W2WBJ6/7-108           YSAMSTDIVLKGTLRKAK-----------------TWNKRFFVLRD---GNPPKLEYYENERKWKVN-KPKRQISLGNPWNIDKKKDTKHEFLIVIFTKDEYFTMAAESADVQQTWISALLKT-
C3ZU02/220-326             --------------REMVTVCMGLGAV---GRSGLTMKKRYFVLHAKSSAGAARLEYFDNEKKWRHGAAPKRTIFLHHCFNINKKDDGKHKHMIVLYTRDECFSLVADTADEHDTWLAVLKDLH
#=GC scorecons             0134334434464577570000000000000000095697798955444344779997759795344449994949566699777396985659874678549457575565445974496360
#=GC scorecons_70          ___________*__**_*_________________*_*******________*******_***______***_*_*_********_****___***__**__*__*_*__*____**__*__*_
#=GC scorecons_80          _______________*_*_________________*__*_****_________******_***______***_*_*____***___*_**___***__**__*____*_______**__*____
#=GC scorecons_90          ___________________________________*__*__***__________***___*_*______***_*_*____**____*_**___**____*__*____________*___*____
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