View in Gene3D

CATH Superfamily 1.25.40.540

TAP42-like family

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TAP42-like family
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: TAP42-like family

According to the literature, structural domains which comprise this superfamily correspond to the structure of TAP42 and related proteins, all involved in the negative regulation of phosphatases. This domain is annotated in InterPro as a positive regulation of the TOR signaling pathway in plants, promoting cell growth in response to nutrient availability, and inhibiting the action of PP2A's catalytic activity PMID:21216945.

The TOR signalling pathway activates a cell-growth program in response to nutrients

GO Diversity

Unique GO annotations
40 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1400 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 4
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 2
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 34
Function
Unique EC:
Unique GO: 40
Taxonomy
Unique Species: 1400
CATH-Gene3D is a Global Biodata Core Resource Learn more...