The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phospholamban
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Cardiac phospholamban

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
77 P26678 (/IPI) P26678 (/IPI) P61014 (/IPI) P61014 (/IPI) P61014 (/IPI) P61014 (/IPI) P61014 (/IPI) P61014 (/IPI) P61014 (/IPI) P61014 (/IPI)
(67 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
67 A4IFH6 (/ISS) P26678 (/ISS) P26678 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS)
(57 more)
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
34 P26678 (/IDA) P26678 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61016 (/IDA)
(24 more)
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
25 P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA)
(15 more)
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
25 P61015 (/IC) P61015 (/IC) P61015 (/IC) P61015 (/IC) P61015 (/IC) P61015 (/IC) P61015 (/IC) P61015 (/IC) P61015 (/IC) P61015 (/IC)
(15 more)
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
25 P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO)
(15 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
25 P61015 (/IPI) P61015 (/IPI) P61015 (/IPI) P61015 (/IPI) P61015 (/IPI) P61015 (/IPI) P61015 (/IPI) P61015 (/IPI) P61015 (/IPI) P61015 (/IPI)
(15 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
25 P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA)
(15 more)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
25 P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA)
(15 more)
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
2 P26678 (/ISS) P26678 (/ISS)
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
2 P26678 (/ISS) P26678 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 P26678 (/ISS) P26678 (/ISS)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
2 P26678 (/ISS) P26678 (/ISS)

There are 54 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of calcium ion transport GO:0051924
Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
67 P26677 (/ISS) P26678 (/ISS) P26678 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS)
(57 more)
Negative regulation of ATPase-coupled calcium transmembrane transporter activity GO:1901895
Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.
65 A4IFH6 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61013 (/ISS) P61013 (/ISS)
(55 more)
Negative regulation of calcium ion import into sarcoplasmic reticulum GO:1902081
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
60 A4IFH6 (/ISS) P26678 (/ISS) P26678 (/ISS) P61013 (/ISS) P61013 (/ISS) P61013 (/ISS) P61013 (/ISS) P61013 (/ISS) P61013 (/ISS) P61013 (/ISS)
(50 more)
Negative regulation of calcium ion binding GO:1901877
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.
52 P26678 (/IDA) P26678 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA)
(42 more)
Negative regulation of calcium ion transmembrane transporter activity GO:1901020
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.
34 P26678 (/IDA) P26678 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61015 (/IDA)
(24 more)
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
27 P26678 (/IMP) P26678 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(17 more)
Regulation of calcium ion transport GO:0051924
Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
27 P26678 (/IDA) P26678 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA)
(17 more)
Negative regulation of ATPase-coupled calcium transmembrane transporter activity GO:1901895
Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.
27 P26678 (/IDA) P26678 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA)
(17 more)
Regulation of the force of heart contraction GO:0002026
Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.
25 P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI)
(15 more)
Regulation of the force of heart contraction GO:0002026
Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
25 P61016 (/IMP) P61016 (/IMP) P61016 (/IMP) P61016 (/IMP) P61016 (/IMP) P61016 (/IMP) P61016 (/IMP) P61016 (/IMP) P61016 (/IMP) P61016 (/IMP)
(15 more)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
25 P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO)
(15 more)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
25 P61016 (/NAS) P61016 (/NAS) P61016 (/NAS) P61016 (/NAS) P61016 (/NAS) P61016 (/NAS) P61016 (/NAS) P61016 (/NAS) P61016 (/NAS) P61016 (/NAS)
(15 more)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
25 P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI)
(15 more)
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
25 P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA)
(15 more)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
25 P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA)
(15 more)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
25 P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO)
(15 more)
Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880
Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881
Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
25 P61016 (/IEP) P61016 (/IEP) P61016 (/IEP) P61016 (/IEP) P61016 (/IEP) P61016 (/IEP) P61016 (/IEP) P61016 (/IEP) P61016 (/IEP) P61016 (/IEP)
(15 more)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
25 P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA)
(15 more)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
25 P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO)
(15 more)
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
25 P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA)
(15 more)
Negative regulation of heart contraction GO:0045822
Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
25 P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI)
(15 more)
Negative regulation of heart contraction GO:0045822
Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Cardiac muscle tissue development GO:0048738
The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.
25 P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI) P61014 (/IGI)
(15 more)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
25 P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA)
(15 more)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
25 P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO)
(15 more)
Regulation of ryanodine-sensitive calcium-release channel activity GO:0060314
Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Regulation of cardiac muscle cell contraction GO:0086004
Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process GO:0086023
A series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Regulation of the force of heart contraction by cardiac conduction GO:0086092
A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Regulation of calcium ion import GO:0090279
Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Negative regulation of calcium ion import GO:0090281
Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
25 P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA)
(15 more)
Regulation of relaxation of muscle GO:1901077
Any process that modulates the frequency, rate or extent of relaxation of muscle.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Negative regulation of ATPase-coupled calcium transmembrane transporter activity GO:1901895
Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Negative regulation of calcium ion import into sarcoplasmic reticulum GO:1902081
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
25 P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP) P61014 (/IMP)
(15 more)
Negative regulation of ATPase activity GO:0032780
Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
9 P26678 (/IDA) P26678 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA)
Negative regulation of calcium ion import into sarcoplasmic reticulum GO:1902081
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
7 P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA) P61012 (/IDA)
Regulation of the force of heart contraction GO:0002026
Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.
2 P26678 (/IC) P26678 (/IC)
Blood circulation GO:0008015
The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.
2 P26678 (/NAS) P26678 (/NAS)
Negative regulation of heart rate GO:0010459
Any process that stops, prevents or reduces the frequency or rate of heart contraction.
2 P26678 (/IMP) P26678 (/IMP)
Negative regulation of ATPase activity GO:0032780
Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
2 P26678 (/ISS) P26678 (/ISS)
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
2 P26678 (/ISS) P26678 (/ISS)
Regulation of cytosolic calcium ion concentration GO:0051480
Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.
2 P26678 (/IC) P26678 (/IC)
Negative regulation of calcium ion transport GO:0051926
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P26678 (/IDA) P26678 (/IDA)
Relaxation of cardiac muscle GO:0055119
The process in which the extent of cardiac muscle contraction is reduced.
2 P26678 (/TAS) P26678 (/TAS)
Regulation of cardiac muscle cell contraction GO:0086004
Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.
2 P26678 (/IC) P26678 (/IC)
Regulation of cardiac muscle cell membrane potential GO:0086036
Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2 P26678 (/IC) P26678 (/IC)
Negative regulation of calcium ion import GO:0090281
Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
2 P26678 (/ISS) P26678 (/ISS)
Negative regulation of calcium ion transmembrane transporter activity GO:1901020
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.
2 P26678 (/ISS) P26678 (/ISS)
Negative regulation of calcium ion binding GO:1901877
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.
2 P26678 (/ISS) P26678 (/ISS)
Regulation of ATPase-coupled calcium transmembrane transporter activity GO:1901894
Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.
2 P26678 (/IDA) P26678 (/IDA)
Regulation of relaxation of cardiac muscle GO:1901897
Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.
2 P26678 (/IC) P26678 (/IC)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sarcoplasmic reticulum membrane GO:0033017
The lipid bilayer surrounding the sarcoplasmic reticulum.
68 A4IFH6 (/ISS) P26677 (/ISS) P26678 (/ISS) P26678 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS) P61012 (/ISS)
(58 more)
Sarcoplasmic reticulum GO:0016529
A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
50 P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA)
(40 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
25 P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA)
(15 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
25 P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA)
(15 more)
Sarcoplasmic reticulum GO:0016529
A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
25 P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO)
(15 more)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
25 P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA)
(15 more)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
25 P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO)
(15 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
25 P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA) P61016 (/IDA)
(15 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
25 P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO) P61014 (/ISO)
(15 more)
Sarcoplasmic reticulum membrane GO:0033017
The lipid bilayer surrounding the sarcoplasmic reticulum.
25 P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA) P61014 (/IDA)
(15 more)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
25 P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA) P61015 (/IDA)
(15 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P26678 (/HDA) P26678 (/HDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 P26678 (/ISS) P26678 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P26678 (/IDA) P26678 (/IDA)
Sarcoplasmic reticulum membrane GO:0033017
The lipid bilayer surrounding the sarcoplasmic reticulum.
2 P26678 (/TAS) P26678 (/TAS)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 P26678 (/ISS) P26678 (/ISS)
Calcium ion-transporting ATPase complex GO:0090534
Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in).
2 P26678 (/IDA) P26678 (/IDA)