# STOCKHOLM 1.0 #=GF ID 1.20.1070.10/FF/000262 #=GF DE Frizzled 2 #=GF AC 1.20.1070.10/FF/000262 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 71.762 #=GS Q9VVX3/254-623 AC Q9VVX3 #=GS Q9VVX3/254-623 OS Drosophila melanogaster #=GS Q9VVX3/254-623 DE Frizzled-2 #=GS Q9VVX3/254-623 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9VVX3/254-623 DR GO; GO:0004888; GO:0005515; GO:0005634; GO:0005886; GO:0005887; GO:0007367; GO:0007411; GO:0007435; GO:0008045; GO:0008585; GO:0016021; GO:0016055; GO:0016201; GO:0016477; GO:0017147; GO:0030165; GO:0031290; GO:0035206; GO:0035293; GO:0042802; GO:0042813; GO:0048675; GO:0050808; GO:0060070; #=GS M9PFW3/255-623 AC M9PFW3 #=GS M9PFW3/255-623 OS Drosophila melanogaster #=GS M9PFW3/255-623 DE Frizzled 2, isoform F #=GS M9PFW3/255-623 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS B7Z072/254-623 AC B7Z072 #=GS B7Z072/254-623 OS Drosophila melanogaster #=GS B7Z072/254-623 DE Frizzled 2, isoform D #=GS B7Z072/254-623 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS A7S003/174-521 AC A7S003 #=GS A7S003/174-521 OS Nematostella vectensis #=GS A7S003/174-521 DE Predicted protein #=GS A7S003/174-521 DR ORG; Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella; Nematostella vectensis; #=GS D6WG76/196-543 AC D6WG76 #=GS D6WG76/196-543 OS Tribolium castaneum #=GS D6WG76/196-543 DE Frizzled 2 #=GS D6WG76/196-543 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS Q7QDV6/254-618 AC Q7QDV6 #=GS Q7QDV6/254-618 OS Anopheles gambiae #=GS Q7QDV6/254-618 DE AGAP010442-PA #=GS Q7QDV6/254-618 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS F7AHD7/125-404 AC F7AHD7 #=GS F7AHD7/125-404 OS Ornithorhynchus anatinus #=GS F7AHD7/125-404 DE Frizzled class receptor 5 #=GS F7AHD7/125-404 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus; Ornithorhynchus anatinus; #=GS H2R050/217-562 AC H2R050 #=GS H2R050/217-562 OS Pan troglodytes #=GS H2R050/217-562 DE Frizzled class receptor 8 #=GS H2R050/217-562 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A0L0CLA4/277-639 AC A0A0L0CLA4 #=GS A0A0L0CLA4/277-639 OS Lucilia cuprina #=GS A0A0L0CLA4/277-639 DE Frizzled-2 #=GS A0A0L0CLA4/277-639 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Oestroidea; Calliphoridae; Luciliinae; Lucilia; Lucilia cuprina; #=GS A0A1B0F9W7/270-632 AC A0A1B0F9W7 #=GS A0A1B0F9W7/270-632 OS Glossina morsitans morsitans #=GS A0A1B0F9W7/270-632 DE Uncharacterized protein #=GS A0A1B0F9W7/270-632 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Hippoboscoidea; Glossinidae; Glossina; Glossina; Glossina morsitans; Glossina morsitans morsitans; #=GS A0A1S4FER6/239-592 AC A0A1S4FER6 #=GS A0A1S4FER6/239-592 OS Aedes aegypti #=GS A0A1S4FER6/239-592 DE GPCR Frizzled/Smoothened Family #=GS A0A1S4FER6/239-592 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Culicinae; Aedini; Aedes; Stegomyia; Aedes aegypti; #=GS B0XF00/236-590 AC B0XF00 #=GS B0XF00/236-590 OS Culex quinquefasciatus #=GS B0XF00/236-590 DE Frizzled-2 precursor #=GS B0XF00/236-590 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Culicinae; Culicini; Culex; Culex; Culex quinquefasciatus; #=GS A0A084W1T5/238-608 AC A0A084W1T5 #=GS A0A084W1T5/238-608 OS Anopheles sinensis #=GS A0A084W1T5/238-608 DE AGAP010442-PA-like protein #=GS A0A084W1T5/238-608 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Anopheles; Laticorn; Myzorhynchus; hyrcanus group; Anopheles sinensis; #=GS A0A182LNA5/254-618 AC A0A182LNA5 #=GS A0A182LNA5/254-618 OS Anopheles coluzzii #=GS A0A182LNA5/254-618 DE Uncharacterized protein #=GS A0A182LNA5/254-618 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles coluzzii; #=GS A0A182YIP9/209-573 AC A0A182YIP9 #=GS A0A182YIP9/209-573 OS Anopheles stephensi #=GS A0A182YIP9/209-573 DE Uncharacterized protein #=GS A0A182YIP9/209-573 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles stephensi; #=GS B4J3D8/268-632 AC B4J3D8 #=GS B4J3D8/268-632 OS Drosophila grimshawi #=GS B4J3D8/268-632 DE GH16736 #=GS B4J3D8/268-632 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; grimshawi group; grimshawi subgroup; Drosophila grimshawi; #=GS B4LDK8/243-611 AC B4LDK8 #=GS B4LDK8/243-611 OS Drosophila virilis #=GS B4LDK8/243-611 DE Uncharacterized protein #=GS B4LDK8/243-611 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GS A0A0M5J631/255-619 AC A0A0M5J631 #=GS A0A0M5J631/255-619 OS Drosophila busckii #=GS A0A0M5J631/255-619 DE Fz2 #=GS A0A0M5J631/255-619 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Dorsilopha; Drosophila busckii; #=GS Q174W8/239-592 AC Q174W8 #=GS Q174W8/239-592 OS Aedes aegypti #=GS Q174W8/239-592 DE AAEL006778-PA #=GS Q174W8/239-592 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Culicinae; Aedini; Aedes; Stegomyia; Aedes aegypti; #=GS A0A182H9U6/231-584 AC A0A182H9U6 #=GS A0A182H9U6/231-584 OS Aedes albopictus #=GS A0A182H9U6/231-584 DE Uncharacterized protein #=GS A0A182H9U6/231-584 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Culicinae; Aedini; Aedes; Stegomyia; Aedes albopictus; #=GS B3NDY1/255-623 AC B3NDY1 #=GS B3NDY1/255-623 OS Drosophila erecta #=GS B3NDY1/255-623 DE Uncharacterized protein #=GS B3NDY1/255-623 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B3M7N4/256-624 AC B3M7N4 #=GS B3M7N4/256-624 OS Drosophila ananassae #=GS B3M7N4/256-624 DE Uncharacterized protein #=GS B3M7N4/256-624 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; Drosophila ananassae; #=GS B4ITN7/176-545 AC B4ITN7 #=GS B4ITN7/176-545 OS Drosophila yakuba #=GS B4ITN7/176-545 DE Uncharacterized protein #=GS B4ITN7/176-545 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS Q29DI2/263-627 AC Q29DI2 #=GS Q29DI2/263-627 OS Drosophila pseudoobscura pseudoobscura #=GS Q29DI2/263-627 DE Uncharacterized protein #=GS Q29DI2/263-627 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; #=GS A0A3B0JS84/264-628 AC A0A3B0JS84 #=GS A0A3B0JS84/264-628 OS Drosophila guanche #=GS A0A3B0JS84/264-628 DE Blast:Frizzled-2 #=GS A0A3B0JS84/264-628 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; #=GS B4N4Q2/266-630 AC B4N4Q2 #=GS B4N4Q2/266-630 OS Drosophila willistoni #=GS B4N4Q2/266-630 DE Uncharacterized protein #=GS B4N4Q2/266-630 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; #=GS B4H945/266-630 AC B4H945 #=GS B4H945/266-630 OS Drosophila persimilis #=GS B4H945/266-630 DE GL20917 #=GS B4H945/266-630 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila persimilis; #=GS B4IG02/254-623 AC B4IG02 #=GS B4IG02/254-623 OS Drosophila sechellia #=GS B4IG02/254-623 DE GM14888 #=GS B4IG02/254-623 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS B4QQD4/253-622 AC B4QQD4 #=GS B4QQD4/253-622 OS Drosophila simulans #=GS B4QQD4/253-622 DE GD12297 #=GS B4QQD4/253-622 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GF SQ 29 Q9VVX3/254-623 ------SCSCRSPLIFLGKEQLLQQQSQMPM-MHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------LLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGA M9PFW3/255-623 -------CSCRSPLIFLGKEQLLQQQSQMPM-MHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------LLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGA B7Z072/254-623 ------SCSCRSPLIFLGKEQLLQQQSQMPM-MHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------LLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGA A7S003/174-521 ------CCSCRPPFVSIAGKNI------------------KPTRAISVGGVPQCAMACNRTYFTHDQDSFASFWIGLWAILCFISTL-VTTLTFLVDMHRFKYPERPIIFLSGCYLMVSVGYII------RLIAGHKQIACDSN------------------GLMRYDTSGPASCTIVFLLVYFFGMASSVWWVILAFTWFLSAGMKWSSEAITNYSQYFHAVAWLVPAIQAIAVLAMSTIDGDPVSGICYVGNHNLQSLVVFVIVPLVVYLVFGTSFLMAGFYSLVRIRKLLRQHG----STKTDKLEKLMIRIGVFSVLYTVPATIVVACYYYELVNRETWERTINCSGCGVT----RVKPDHSVFIIKYFMALVVGITSGFWIWSGKTIESWRNFCARLSGT D6WG76/196-543 ------KCQCQHPLVSLGKDPSL-----------------LNLS---VLDPATCAAPCRATYFNSEEKEFTTVWITLWSSLCAASTL-MTLTTFFIETERFKYPERPIVFLSACYFLVSVGYLI------RVGVGHEEVACEG-------------------PVIRYSSTGANPCSLVFLLVYFFGMASSIWWVVLSFTWFLAAGLKWGNEAIASYAEYFHVAAWLIPTLQTVAVFVSGAVDGDPVAGICYVGNMNMENLRTFVLAPLFIYLLLGTTFLIAGFVSLFRIRNVIKKQGGAGAGSKADKLEKLMIRIGIFSVLYTVPASIVIACHLYENAFHNEWMLSAACTCPSA-----KVRPIYSVLMLKYFMALAVGITSGVWIWSGKTLDSWRRLWRRLFGR Q7QDV6/254-618 ------MCRCREPLVTLGRESSTT-----TL-LHHHGSLSSNQSVERVGDVQNCAIPCRGAFFTQEEKDFAGIWIALWSGLCGISTL-MTLTTFLIDTERFKYPERPIVFLSACYFIVSCGYLT------RIFLGHDEIACDG-------------------KSIKYPSTGQSSCTMIFIMIYFFGMASSIWWVILSFTWFLAAGLKWGNEAISKHSQYFHLAAWLIPTVQTVSVLLRPAVDGDPVAGICYVGNTSVENLKNFVLAPLFMYLVVGTTFLMAGFVSLFRIRSVIKQQGGIGAGSKADKLEKLMIRIGIFSVLYTVPATIVIGCHLYEASYFEDWMTGLTCPCKVAPGL--RQKPLYSVLMLKYFMALAVGITSGVWIWSGKTVDSWRRLWRRLFGS F7AHD7/125-404 -----------HPLFGK----------------------------VRTGRAHTGPLPCHQPAFGPDERAFTSFWLGLWSVLCFFSTA-TTVATFLIDTDRFRYPERPIVFLAACYLFVSLGFLV------RLAAGHASVACSRDH-----------------GHVRYETTGPALCTAVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLIPGVQSVAVLALSAVDGDPVAGICYVGNQNLDYLRGFVLAPLVVYLLTGTLFLLAGFVSLFRIRSVIKQ-----GGTKTDKLEKLMIRIGVFTVLYTVPAGAVVACYLYEQHQREGWERILS--------------------------------------------------------- H2R050/217-562 ----------RPPCYEL-------------------------RSVSRLHRLDGS--------------------LMLWSVLCFVSTLPPSPPSLSLQRALQSDPERPIISPLGLLPLSMVGKAVASAAVARQSGGALEARGRGRGGWGAGRGGYGGAWSAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDG---PTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESWRSLCTRCCW- A0A0L0CLA4/277-639 -------CSCRPPLILLGKEAQLMQP---P--LH--YPWYMNSTVSRIAGVQNCAIPCKGPFFTNEEKEFAGIWITLWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------KNFLQNEEIACDG-------------------RLLKESSTGPHSCTLVFLMTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQIKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGQ A0A1B0F9W7/270-632 -------CTCRPPLILLGKEALMQQP---P--MH--YPWYQNSTVARIAGVQNCAIPCKGPFFTNDEKEFAGIWITLWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------KNFLQNEEIACDG-------------------RLLKESSTGPHSCTLVFLMTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPAVIVIGCYLYEAAYFEDWIRALACPCAQIKGP--GKKPLYWVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGQ A0A1S4FER6/239-592 ------MCRCREPLVTLGKEN---------L-LH-------NQSVERVGDVINCAIPCRGAFFSQEEKDFAGVWIALWSGLCGISTL-MTLTTFLIDTERFKYPERPIVFLSACYFIVSCGYLT------KLFLGHDEIACDG-------------------KAIKYPSMGQSSCTMIFIMIYFFGMASSIWWVILSFTWFLAAGLKWGNEAISKHSQYFHLAAWLIPTVQSVSVLLRPAVDGDPIAGICYVGNTSVENLKNFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGIGAGSKADKLEKLMIRIGIFSVLYTVPATIVIGCHLYEANFTEDWMTGLTCPCKAGTGI--RQKPLYSVLMLKYFMALAVGITSGVWIWSGKTVESWRRLWRRLFGS B0XF00/236-590 ------MCRCREPLVTLGKES---------L-LH------NNQSVERVGDVLNCAIPCRGAFFSQEEKDFAGVWIALWSGLCGISTL-MTLTTFLIDTERFKYPERPIVFLSACYFIVSCGYLT------RLFLGQDEIACDG-------------------KGIKYPAMGQSSCTMVFIMIYFFGMASSIWWVILSFTWFLAAGLKWGNEAISKHSQYFHLAAWLIPTVQTVSVLLRPAVDGDPVAGICYVGNTSVENLKNFVLAPLFVYLLVGTTFLMAGFVSLFRIRSVIKQQGGIGAGSKADKLEKLMIRIGIFSVLYTVPATIVIGCHLYEANYFEDWMTGLTCPCKAQTGI--RQKPLYSVLMLKYFMALAVGITSGVWIWSGKTVESWRRLWRRLFGS A0A084W1T5/238-608 ERTKECMCRCREPLVALGRESSTT-----TL-LHHHGSLSANQSVERVGDVQNCAIPCRGAFFTQEEKDFAGIWIALWSGLCGISTL-MTLTTFLIDTERFKYPERPIVFLSACYFIVSCGYLT------RIFLGHDEIACDG-------------------KSIKYPSTGQSSCTMIFIMVYFFGMASSIWWVILSFTWFLAAGLKWGNEAISKHSQYFHLAAWLIPTVQTVSVLLRPAVDGDPVAGICYVGNTSVEHLKNFVLAPLFMYLVVGTTFLMAGFVSLFRIRSVIKQQGGIGAGSKADKLEKLMIRIGIFSVLYTVPATIVIGCHLYEASYFEDWMTGLTCPCKVAPGL--RQKPLYSVLMLKYFMALAVGITSGVWIWSGKTVDSWRRLWRRLFGS A0A182LNA5/254-618 ------MCRCREPLVTLGRESSTT-----TL-LHHHGSLSSNQSVERVGDVQNCAIPCRGAFFTQEEKDFAGIWIALWSGLCGISTL-MTLTTFLIDTERFKYPERPIVFLSACYFIVSCGYLT------RIFLGHDEIACDG-------------------KSIKYPSTGQSSCTMIFIMIYFFGMASSIWWVILSFTWFLAAGLKWGNEAISKHSQYFHLAAWLIPTVQTVSVLLRPAVDGDPVAGICYVGNTSVENLKNFVLAPLFMYLVVGTTFLMAGFVSLFRIRSVIKQQGGIGAGSKADKLEKLMIRIGIFSVLYTVPATIVIGCHLYEASYFEDWMTGLTCPCKVAPGL--RQKPLYSVLMLKYFMALAVGITSGVWIWSGKTVDSWRRLWRRLFGS A0A182YIP9/209-573 ------MCRCREPLVTLGRESTTT-----TL-LHHHGSLSSNQSVERVGDVQNCAIPCRGAFFTQEEKDFAGIWIALWSGLCGISTL-MTLTTFLIDTERFKYPERPIVFLSACYFIVSCGYLT------RIFLGHDEIACDG-------------------KSIKYPSTGQSSCTMIFIMIYFFGMASSIWWVILSFTWFLAAGLKWGNEAISKHSQYFHLAAWLIPTVQTVSVLLRPAVDGDPVAGICYVGNTSVENLKNFVLAPLFMYLVVGTTFLMAGFVSLFRIRSVIKQQGGIGAGSKADKLEKLMIRIGIFSVLYTVPATIVIGCHLYEASYFEDWMTGLTCPCKAAPGL--RQKPLYSVLMLKYFMALAVGITSGVWIWSGKTVDSWRRLWRRLFGS B4J3D8/268-632 ------SCSCRSPLIVLGKEQLMQQS---PM-LH--HHWYMNLTVQRIAGVQNCAIPCKGPFFTNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------RLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGA B4LDK8/243-611 --GKECTCSCRSPLIVLGKEQLMQQS---PM-LH--HHWYMNLTVQRIAGVQNCAIPCKGPFFTNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------RLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGA A0A0M5J631/255-619 -------CSCRSPLIVLGKEQLMQQS---PMSMH--HPWYMNLTVQRIAGVQNCAIPCKGPFFTNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------RLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGA Q174W8/239-592 ------MCRCREPLVTLGKEN---------L-LH-------NQSVERVGDVINCAIPCRGAFFSQEEKDFAGVWIALWSGLCGISTL-MTLTTFLIDTERFKYPERPIVFLSACYFIVSCGYLT------KLFLGHDEIACDG-------------------KAIKYPSMGQSSCTMIFIMIYFFGMASSIWWVILSFTWFLAAGLKWGNEAISKHSQYFHLAAWLIPTVQSVSVLLRPAVDGDPIAGICYVGNTSVENLKNFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGIGAGSKADKLEKLMIRIGIFSVLYTVPATIVIGCHLYEANFTEDWMTGLTCPCKAGTGI--RQKPLYSVLMLKYFMALAVGITSGVWIWSGKTVESWRRLWRRLFGS A0A182H9U6/231-584 ------MCRCREPLVTLGKEN---------L-LH-------NQSVERVGDVINCAIPCRGAFFSQEEKDFAGVWIALWSGLCGISTL-MTLTTFLIDTERFKYPERPIVFLSACYFIVSCGYLT------RLFLGHDEIACDG-------------------KAIKYPSMGQSSCTMIFIMIYFFGMASSIWWVILSFTWFLAAGLKWGNEAISKHSQYFHLAAWLIPTVQSVSVLLRPAVDGDPIAGICYVGNTSVENLKNFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGIGAGSKADKLEKLMIRIGIFSVLYTVPATIVIGCHLYEANFTEDWMTGLTCPCKAGTGI--RQKPLYSVLMLKYFMALAVGITSGVWIWSGKTVESWRRLWRRLFGS B3NDY1/255-623 -------CSCRSPLIFLGKEQLLQQQSQMPM-MHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------LLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGA B3M7N4/256-624 -------CSCRSPLIFLGKEQLMQQQSQSPM-MHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------LLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGA B4ITN7/176-545 ------SCSCRSPLIFLGKEQLLQQQSQMPM-MHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------LLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGA Q29DI2/263-627 ------ACSCQSPLISLGKEQLLQQS---PM-RH--HHWYMNLTVQRIAGVPNCAIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------HLLKESSTGPHSCTLVFLLTYFFGMASSIWWVILSLTWFLAAGLKWGNEAITKHSQYFHLAAWLFPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKKFVLGPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GRKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGA A0A3B0JS84/264-628 ------ACSCQSPLISLGKEQLMQQS---PM-RH--HHWYMNLTVQRIAGVPNCAIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------HLLKESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GRKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGA B4N4Q2/266-630 ------TCSCRSPLIVLGKEQLMQQS---PM-MH--HHWYMNLTVQRIAGVPNCAIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------RLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAPVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGA B4H945/266-630 ------ACSCQSPLISLGKEQLLQQS---PM-RH--HHWYMNLTVQRIAGVPNCAIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------HLLKESSTGPHSCTLVFLLTYFFGMASSIWWVILSLTWFLAAGLKWGNEAITKHSQYFHLAAWLFPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKKFVLGPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GRKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLFGA B4IG02/254-623 ------SCSCRSPLIFLGKEQLLQQQSQMPM-MHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------LLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGA B4QQD4/253-622 ------SCSCRSPLIFLGKEQLLQQQSQMPM-MHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTL-MTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLS------RNFLQNEEIACDG-------------------LLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGP--GKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGA #=GC scorecons 000000163664975375453221100002202400111125346375456367556745457445665765477599859944997068668857776777799999777677765755977400000083555547777670000000000000000000345744669646985796759999999989998987999989979988999557889997899979688676986467899997599999994646596499879967996699699799979989997888866635574977999999998979799999996797696799545476944465766333343004467476766677776767777776767777756777556576463 #=GC scorecons_70 __________*_**__*_____________________________*___*__*__**____*___*__**__**_***_**__***_******_*********************_*__***_______*______******______________________*__***__***_****_*******************************__*********************__********_*******_*_*_**_***********_************************___*_*********************************____*_*___*_***__________**_*_*_********_**************_****____*__*_ #=GC scorecons_80 ____________*_________________________________*__________*____*______*___**_***_**__***__*__**_**__************_***__*__*_*_______*______*_**_*___________________________*___**_**___*******************************__*************_**_*_**___******__*******_____*__******__**__**_******************______*_*_*********************_***_*_***____*_*_____*_____________*___*___****_*_******_*_*****__***____*____ #=GC scorecons_90 ____________*_______________________________________________________________***_**__**_______*_________*****____________*_________*_______________________________________*___**__*___***************_*******_*******___*****_****_*__*___**____*****__*******_____*__***_**__**__**_**_***_******_****________*__**********_*_*******__*__*__**______*______________________________________________________________ //