# STOCKHOLM 1.0 #=GF ID 1.10.3080.10/FF/000025 #=GF DE Chloride channel protein #=GF AC 1.10.3080.10/FF/000025 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 77.519 #=GS Q389H3/65-101_140-464_544-676 AC Q389H3 #=GS Q389H3/65-101_140-464_544-676 OS Trypanosoma brucei brucei TREU927 #=GS Q389H3/65-101_140-464_544-676 DE Chloride channel protein #=GS Q389H3/65-101_140-464_544-676 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q389H3/65-101_140-464_544-676 DR GO; GO:0005179; GO:0005247; GO:0005576; GO:0005737; GO:0005768; GO:0005783; GO:0006821; GO:0016020; #=GS Q381B7/106-452_493-642 AC Q381B7 #=GS Q381B7/106-452_493-642 OS Trypanosoma brucei brucei TREU927 #=GS Q381B7/106-452_493-642 DE Chloride channel protein #=GS Q381B7/106-452_493-642 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q381B7/106-452_493-642 DR GO; GO:0005247; GO:0005737; GO:0005783; GO:0006821; GO:0016020; GO:0031981; GO:0097014; #=GS A4I8X1/173-209_266-563_684-807 AC A4I8X1 #=GS A4I8X1/173-209_266-563_684-807 OS Leishmania infantum #=GS A4I8X1/173-209_266-563_684-807 DE Chloride channel protein #=GS A4I8X1/173-209_266-563_684-807 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS A0A1G4I7E8/106-452_493-642 AC A0A1G4I7E8 #=GS A0A1G4I7E8/106-452_493-642 OS Trypanosoma equiperdum #=GS A0A1G4I7E8/106-452_493-642 DE Chloride channel protein #=GS A0A1G4I7E8/106-452_493-642 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; #=GS Q4Q484/30-66_123-413_526-667 AC Q4Q484 #=GS Q4Q484/30-66_123-413_526-667 OS Leishmania major #=GS Q4Q484/30-66_123-413_526-667 DE Chloride channel protein #=GS Q4Q484/30-66_123-413_526-667 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS E9B3U0/30-66_123-420_527-667 AC E9B3U0 #=GS E9B3U0/30-66_123-420_527-667 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9B3U0/30-66_123-420_527-667 DE Chloride channel protein #=GS E9B3U0/30-66_123-420_527-667 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS E9BQ41/173-209_266-563_684-807 AC E9BQ41 #=GS E9BQ41/173-209_266-563_684-807 OS Leishmania donovani BPK282A1 #=GS E9BQ41/173-209_266-563_684-807 DE Chloride channel protein #=GS E9BQ41/173-209_266-563_684-807 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS Q4Q4T5/102-459_500-645 AC Q4Q4T5 #=GS Q4Q4T5/102-459_500-645 OS Leishmania major #=GS Q4Q4T5/102-459_500-645 DE Chloride channel protein #=GS Q4Q4T5/102-459_500-645 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS E9AHM3/102-460_501-646 AC E9AHM3 #=GS E9AHM3/102-460_501-646 OS Leishmania infantum #=GS E9AHM3/102-460_501-646 DE Chloride channel protein #=GS E9AHM3/102-460_501-646 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS A0A3Q8IH43/102-460_501-646 AC A0A3Q8IH43 #=GS A0A3Q8IH43/102-460_501-646 OS Leishmania donovani #=GS A0A3Q8IH43/102-460_501-646 DE Chloride channel protein #=GS A0A3Q8IH43/102-460_501-646 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS E9BPA7/102-460_501-646 AC E9BPA7 #=GS E9BPA7/102-460_501-646 OS Leishmania donovani BPK282A1 #=GS E9BPA7/102-460_501-646 DE Chloride channel protein #=GS E9BPA7/102-460_501-646 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GF SQ 11 Q389H3/65-101_140-464_544-676 ---WFIWVFVVVIGIAVSFTAIVVVALLHVFASVRYELLGG----------------------------------------------ISPRSYMKGYLMWVSFSFVTSLISSVICICVPGSVGAGMPEVMAYLNGVDYPMLGSFGVLLAKIASVVFSVASGVCTGHCGTLMLTGAMVGAQT-LQRRRWIQIEHVNIIECFRNPRDRRTIVVIGAAAGIASAFNVSIGGLMVVVELISTTIPVRFALYVFAASLVSSLFIQVYFSHFLYFAGRDRTGYSSGELISELVQVFASTIPFEQIVRMHILYFIPTVVIGFICGALSGVYVRLSWFALVVRRHLEQRFKVRAFRALLPVAFTVAYVSLHYWMVVAFGSAGWSPPSSALNPTDNTTAG------GLTTLRWGNSSAVSPHFVDTQLSLPVLMIFLLIYYTSSAIFLGISPCGDTVFPTLVVGATVGRIVGLVVFLIVSPGS--RSSWADPGIFALIGAGSFVGGTTGLAFSICTILMESTGQFQHMLPLMVGIMIAKKTAEIFTHNINAVLLEARCVPML- Q381B7/106-452_493-642 EPRWLKWVMFIAVGICVGLWSVLLFQTLEYLERRK----RGMLR----TYLHETHGR--------GGTEAQTVGGGAGFPMRSTPSGVSWAVAGKCYIIYILWCAGFALLSSLCCLVMPTAAGSGVPEVMAYLNGVMFPRVFNIRNLIVKTLSCIFVVSAGVPVGAEGPIIHIGSLIGAGLPTGRSRTLNCGATSLLSTFRNPRDMRSFISAGAACGVTSAFSAPIGGLLFVMEEVATFFSVRLACMVFVSCLACMCVIQIVNSYMSGWHLLAQSPMTHGEFLPSAIAMFIVNNVPGNHVPLNVYTFIPTVVGSLALGLLAVLYTVSSVRFLRWRR--ERLFPNTFLRVLEPCLFSLAYNTVCYVATLALMG-----------PYN-----------SIRVLFSRHTTGLIP--------WYACLLQLMLYTFSSSYAGGMFVSCGTVIPSLFIGAMGGRLVGTLFN---------NEVWADPGVLSLIGAASYFSGISRLSFSLIVIMMEMTADLTHITCLMVGVVFARALADRFCHSLYHSLLDLKSVPFLE A4I8X1/173-209_266-563_684-807 ---WFMWVFVVVLGVATSALSVGMMTLLHVLNSVRYELFGA-----------------------------------------------SPRWYWSGYLLWVAFAVCTSAIASGVCYLVPQSVGSGIPEVRAFLNGVSYPMMRSTRVLVAKTVAVVFTVASGVCTDHYGHLMLAGAMLGSQL-LQRRHGIRCYHVHFVDCFRNPRDRRTVLVIGAAAGIAAAFCVSVGGLLVILELLSAVFPVRFALYVFAACLLSTLSTQVYWSYCMNFDSPYR--LHGGLLLREVVVLFRSHLPFGQHAVMNLIAFIPAFVIGLCSGACAVGFVRLSWVALYCRRLLEVRLRTKAIRYVLPILFTLVYVSVHYWVAVAFSA--------EPVPGEKMPSAVGEDS--------------LP--------WHALLTFTVIYFFASAVYSGLALCGDTILPSLVIGAAIGRCIGAAVHSVAVAHSTDAATWADPGVFALFGAGSFVSATSGLSFGIGAILIECTADFRHLLPLMFAIAVARRVLLRWARDVHT------------ A0A1G4I7E8/106-452_493-642 EPRWLKWVMFIAVGICVGLWSVLLFQTLEYLERRK----RGMLR----TYLHETHGR--------GGTEAQTVGGGAGFPMRSTPSGVSWAVAGKCYIIYILWCAGFALLSSLCCLVMPTAAGSGVPEVMAYLNGVMFPRVFNIRNLIVKTLSCIFVVSAGVPVGAEGPIIHIGSLIGAGLPTGRSRTLNCGATSLLSTFRNPRDMRSFISAGAACGVTSAFSAPIGGLLFVMEEVATFFSVRLACMVFVSCLACMCVIQIVNSYMSGWHLLAQSPMTHGEFLPSAIAMFIVNNVPGNHVPLNVYTFIPTVVGSLALGLLAVLYTVSSVRFLRWRR--ERLFPNTFLRVLEPCLFSLAYNTVCYVATLALMG-----------PYN-----------SIRVLFSRHTTGLIP--------WYACLLQLMLYTFSSSYAGGMFVSCGTVIPSLFIGAMGGRLVGTLFN---------NEVWADPGVLSLIGAASYFSGISRLSFSLIVIMMEMTADLTHITCLMVGVVFARALADRFCHSLYHSLLDLKSVPFLE Q4Q484/30-66_123-413_526-667 ---WFMWVFVVVLGVVTSALSVGMMTLLHVLNSVRYELFGA-----------------------------------------------SPRWYWSGYLLWVAFAVCTSAIASGMCYLVPQSVGSGIPEVRAFLNGVSYPMMRSTRVLVAKTVAVVFTVASGVCTDHYSHLMLAGAMLGSQL-LQRRHGIRCYHVHFVDYFRNPRDHRTVLVIGAAAGIAAAFCVSVGGLLVILELVSAVFPVRFALYVFAACLLSTLSTQMYWSYCMNFDSPYR--LHGGLLLRE-VVLFRSHLPFGQHAAMNLMAYIPAFVIGLCSGACAVGFVRLSWVALYCRRLLEVRLRTKVIRYVLPILFTLVYVSVHYWVAVAFSA--------ESGPGDTMPSS------TLQTLLSQRTEYLLP--------WPALLTFSVIYFFASAVYSGLALCGDIILPSLVIGAAIGRCIGAAVHSVAVAHSKDAATWADPGVFALFGAGSFVSATSGLSFSIGAILIECTADFRHLLPLMFSIAVARRVLLRWGRDVHTVYLE-------- E9B3U0/30-66_123-420_527-667 ---WFMWVFVVVLGVATSALSVGMITLLHVLNSVRYELFGA-----------------------------------------------SPRWYWSGYLLWVAFAVCTSAIASAVCYLVPQSVGSGIPEVRAFLNGVSYPMMRSTRVLVAKTVAVVFTVASGVCTDHYGHLMLAGAMLGSQL-LQRRHGIRCYHVHFVDFFRNPRDRRTVLVIGAAAGIAAAFCVSVGGLLVILELLSAVFPVRFALYVFAACLLSTLSTQVYWSYSMNFDSPYR--LHGGVLLREVVVLFRSHLPFGQHAAMNLMAFIPACAIGLCSGACAVGFVRLSWVALYCRRLLEIRLRTKVIRYVLPILFTLVYVSVHYWVAVAFSA--------EVAPGEKTPSAVGEDSSTLQTLLSQRAEYLLP--------WPALLTFSVIYFFASAVYSGLALCGDTILPSLVIGAAIGRCIGAAVHSVAAAHSTDAATWADPGVFALFGAGSFVSATSGLSFGIGAILIECTADFRHLLPLMFAIAVARRVLLQWGRDVHTMYL--------- E9BQ41/173-209_266-563_684-807 ---WFMWVFVVVLGVATSALSVGMMTLLHVLNSVRYELFGA-----------------------------------------------SPRWYWSGYLLWVAFAVCTSAIASGVCYLVPQSVGSGIPEVRAFLNGVSYPMMRSTRVLVAKTVAVVFTVASGVCTDHYGHLMLAGAMLGSQL-LQRRHGIRCYHVHFVDCFRNPRDRRTVLVIGAAAGIAAAFCVSVGGLLVILELLSAVFPVRFALYVFAACLLSTLSTQVYWSYCMNFDSPYR--LHGGLLLREVVVLFRSHLPFGQHAVMNLIAFIPAFVIGLCSGACAVGFVRLSWVALYCRRLLEVRLRTKAIRYVLPILFTLVYVSVHYWVAVAFSA--------EPVPGEKMPSAVGEDS--------------LP--------WHALLTFTVIYFFASAVYSGLALCGDTILPSLVIGAAIGRCIGAAVHSVAVAHSTDAATWADPGVFALFGAGSFVSATSGLSFGIGAILIECTADFRHLLPLMFAIAVARRVLLRWARDVHT------------ Q4Q4T5/102-459_500-645 AKGWLRLLMFVLIGLAVGGWSLLVLQTLDYLAEVKLDAVQGVVRSRNSTYPPFNASKFYMSTLRNSRHE-GGDDEKAAVVLRT----LSWSALLHGGVLYTMWGVLMALLSSLCCLVMPSAAGSGIPDVMAYLNGVMFPRIFNIRNLVVKTLSCILAVSAGLPVGTEGPMIHMGSLIGAGLPTGRSRSLGCSATSVFDLFRNPRDQRDFISAGAACGLTSAFSSPLGGMLFVLEEMATHFSVRLAWLVFLSCLSCMWIIQACNSFLSGWHLVDRSAMALGDLREASIAMFYIDTVRENTVSLYTYTFIPTVMVAVLSGLLAVAYTVSSIRFSRWRS--RCLFPTALYRVLEPCVFASLFSTACYVATLTMTS-----------PYN-----------LLRLLFSRRSVGLFP--------AWSLFLHLAIYVVGSSYAGGMFISCGTVIPSLLIGAVEGRLIGVLFQ---------RPLWADEGVVALIGAAAYFAGISRLTFALVVVMMELTADVSHITCLMLGILLAKGIADKCCHSFYHASLEVKAV---- E9AHM3/102-460_501-646 AKGWLRLLMFVLIGLAVGGWSLLVFQTLDYLAEVKLDAVQGVVRSRNSTYPPFNASRICMSALCNSGHEDGGDDGKAAVVLRA----LSWSALLHGGVLYTMWGVLMALLSSLCCLVMPSAAGSGIPDVMAYLNGVMFPRIFNIRNLVVKTLSCILAVSAGLPVGTEGPMIHMGSLIGAGLPTGRSRSLGCSATSVFDLFRNPRDQRDFISAGAACGLTSAFSSPLGGMLFVLEEMATHFSVRLAWLVFLSCLSCMWIIQTCNSFLSGWHLVDRSAMALGDLREASIAMFYIDTVPENTVSLYTYTFIPTVMVAVLSGLLAVAYTVSSIRFSRWRS--RCLFPTTLYRVLEPCVFASLFSTACYVATLTMTS-----------PYN-----------LLRLLFSRRSAGLFP--------AWSLLLHLAIYVVGSSYAGGMFISCGTVIPSLLIGAVEGRLIGVLFQ---------RPVWADEGVVALIGAAAYFAGISRLTFALVVVMMELTADVSHITCLMLGILVAKSIADKCCHSFYHASLEVKAV---- A0A3Q8IH43/102-460_501-646 AKGWLRLLMFVLIGLAVGGWSLLVFQTLDYLAEVKLDAVQGVVRSRNSTYPPFNASRICMSALCNSGHEDGGDDGKAAVVLRT----LSWSALLHGGVLYTMWGVLMALLSSLCCLVMPSAAGSGIPDVMAYLNGVMFPRIFNIRNLVVKTLSCILAVSAGLPVGTEGPMIHMGSLIGAGLPTGRSRSLGCSATSVFDLFRNPRDQRDFISAGAACGLTSAFSSPLGGMLFVLEEMATHFSVRLAWLVFLSCLSCMWIIQTCNSFLSGWHLVDRSAMALGDLREASIAMFYIDTVPENTVSLYTYTFIPTVMVAVLSGLLAVAYTVSSIRFSRWRS--RCLFPTTLYRVLEPCVFASLFSTACYVATLTMTS-----------PYN-----------LLRLLFSRRSAGLFP--------AWSLLLHLAIYVVGSSYAGGMFISCGTVIPSLLIGAVEGRLIGVLFQ---------RPVWADEGVVALIGAAAYFAGISRLTFALVVVMMELTADVSHITCLMLGILVAKSIADKCCHSFYHASLEVKAV---- E9BPA7/102-460_501-646 AKGWLRLLMFVLIGLAVGGWSLLVFQTLDYLAEVKLDAVQGVVRSRNSTYPPFNASRICMSALCNSGHEDGGDDGKAAVVLRT----LSWSALLHGGVLYTMWGVLMALLSSLCCLVMPSAAGSGIPDVMAYLNGVMFPRIFNIRNLVVKTLSCILAVSAGLPVGTEGPMIHMGSLIGAGLPTGRSRSLGCSATSVFDLFRNPRDQRDFISAGAACGLTSAFSSPLGGMLFVLEEMATHFSVRLAWLVFLSCLSCMWIIQTCNSFLSGWHLVDRSAMALGDLREASIAMFYIDTVPENTVSLYTYTFIPTVMVAVLSGLLAVAYTVSSIRFSRWRS--RCLFPTTLYRVLEPCVFASLFSTACYVATLTMTS-----------PYN-----------LLRLLFSRRSAGLFP--------AWSLLLHLAIYVVGSSYAGGMFISCGTVIPSLLIGAVEGRLIGVLFQ---------RPVWADEGVVALIGAAAYFAGISRLTFALVVVMMELTADVSHITCLMLGILVAKSIADKCCHSFYHASLEVKAV---- #=GC scorecons 11196456557559555634764544595474467343346112000022110111100000000111201111112111121000029443434645655454634656694494569466979797959799994795536575966975657649669655643856654966696572559564647355544639999994945655999595669954659968576945663769969449946794654469443963445444472154393744437569344454654636544589965555535954774754593445449511634646444946494595447465594556654500000000100935011110000002432534333224490000000043567545479455964449645656875979589943994794554111011101444999598579599667556675959563576693977549655995574597455454465464225312130000 #=GC scorecons_70 ___**__*__*__*______*______*__*__**_____________________________________________________*______*__*__________*_*__*__**___*******_******_**_____*_**_**___**_*__**_____*__*__*_*_*__*___*_*_*_*______*_******_*_____***_*_*_**____****_***___*_*_****__**__**______*___**________*_____*_*____*__*___________*____****_______*__**_*___*______*______*_____*_*_*__*___*____*___**______________*___________________________*___________**____**___*____*______**_***_***__**_**________________***_**_**_**_**____*_*_*_*__****_***__*___**__*__**_______*________________ #=GC scorecons_80 ___*______*__*______*______*__*_________________________________________________________*______________________*__*___*___***_***_******_**_____*_*__**______*__*______*_____*___*__*___*_____*________******_*_____***_*___**____**_*___*_____*_**_*__**__**______*___*_________*_____*_*_______*________________***________*__**_*___*______*____________*___*__*___*____*___________________*___________________________*____________*____**___*____*______*__***_***__**_**________________***_**_**_**__*____*_*_*____*__*_***__*___**__*__*_________________________ #=GC scorecons_90 ___*_________*_____________*____________________________________________________________*______________________*__*___*___*_*_*_*_*_****__*_______*__*_______*__*____________*___*______*______________******_*_____***_*___**____**_____*_______**_*__**___*______*___*_______________*_________*________________***________*_________*______*____________*___*__*________*___________________*___________________________*__________________*___*____*_________*_*_***__**__*________________***_**__*_**_________*_*_______*_*____*___**_____*_________________________ //