CATH Domain 6o9zL02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.190	Translation initiation factor 2; subunit 1; domain 2

Domain Context

CATH Clusters

Superfamily	Translation initiation factor 2; subunit 1; domain 2
Functional Family	Eukaryotic translation initiation factor 2 subunit 1

Enzyme Information

UniProtKB Entries (1)

EI2BE_HUMAN

Homo sapiens

Translation initiation factor eIF-2B subunit epsilon

PDB Structure

PDB	6O9Z
External Links	PDBSum Proteopedia
Method	ELECTRON MICROSCOPY
Organism
Primary Citation	eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Kenner, L.R., Anand, A.A., Nguyen, H.C., Myasnikov, A.G., Klose, C.J., McGeever, L.A., Tsai, J.C., Miller-Vedam, L.E., Walter, P., Frost, A. Science