CATH Domain 6i6zA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.630	Aminopeptidase
	3.40.630.10	Zn peptidases

Domain Context

CATH Clusters

Superfamily	Zn peptidases
Functional Family	Carboxypeptidase A1

Enzyme Information

3.4.17.1

Carboxypeptidase A.

based on mapping to UniProt P15085

Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.

-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.

UniProtKB Entries (1)

P15085

CBPA1_HUMAN

Homo sapiens

Carboxypeptidase A1

PDB Structure

PDB	6I6Z
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes. Covaleda, G., Gallego, P., Vendrell, J., Georgiadis, D., Lorenzo, J., Dive, V., Aviles, F.X., Reverter, D., Devel, L. J. Med. Chem.