CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.10 | Jelly Rolls |
Domain Context
CATH Clusters
| Superfamily | Jelly Rolls |
| Functional Family | 3-hydroxyanthranilate 3,4-dioxygenase |
Enzyme Information
| 1.13.11.6 |
3-hydroxyanthranilate 3,4-dioxygenase.
based on mapping to UniProt P46952
3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde.
-!- The product of the reaction spontaneously rearrange to quinolinic acid (quin). -!- Formerly EC 1.13.1.6.
|
UniProtKB Entries (1)
| P46952 |
3HAO_HUMAN
Homo sapiens
3-hydroxyanthranilate 3,4-dioxygenase
|
PDB Structure
| PDB | 5TK5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.
Acta Crystallogr D Struct Biol
|
