CATH Domain 5mr4A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.90	Cystine Knot Cytokines, subunit B
	2.10.90.10	Cystine-knot cytokines

Domain Context

CATH Clusters

Superfamily	Cystine-knot cytokines
Functional Family	neurturin

Enzyme Information

UniProtKB Entries (1)

GFRA2_HUMAN

Homo sapiens

GDNF family receptor alpha-2

PDB Structure

PDB	5MR4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling. Sandmark, J., Dahl, G., Oster, L., Xu, B., Johansson, P., Akerud, T., Aagaard, A., Davidsson, P., Bigalke, J.M., Winzell, M.S., Rainey, G.J., Roth, R.G. J. Biol. Chem.