CATH Domain 5jz7I00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin lambda variable 2-8

Enzyme Information

UniProtKB Entries (1)

NGF_HUMAN

Homo sapiens

Beta-nerve growth factor

PDB Structure

PDB	5JZ7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Dobson, C.L., Devine, P.W., Phillips, J.J., Higazi, D.R., Lloyd, C., Popovic, B., Arnold, J., Buchanan, A., Lewis, A., Goodman, J., van der Walle, C.F., Thornton, P., Vinall, L., Lowne, D., Aagaard, A., Olsson, L.L., Ridderstad Wollberg, A., Welsh, F., Karamanos, T.K., Pashley, C.L., Iadanza, M.G., Ranson, N.A., Ashcroft, A.E., Kippen, A.D., Vaughan, T.J., Radford, S.E., Lowe, D.C. Sci Rep