CATH Domain 5jz7A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.90	Cystine Knot Cytokines, subunit B
	2.10.90.10	Cystine-knot cytokines

Domain Context

CATH Clusters

Superfamily	Cystine-knot cytokines
Functional Family	Brain-derived neurotrophic factor

Enzyme Information

UniProtKB Entries (1)

NGF_HUMAN

Homo sapiens

Beta-nerve growth factor

PDB Structure

PDB	5JZ7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Dobson, C.L., Devine, P.W., Phillips, J.J., Higazi, D.R., Lloyd, C., Popovic, B., Arnold, J., Buchanan, A., Lewis, A., Goodman, J., van der Walle, C.F., Thornton, P., Vinall, L., Lowne, D., Aagaard, A., Olsson, L.L., Ridderstad Wollberg, A., Welsh, F., Karamanos, T.K., Pashley, C.L., Iadanza, M.G., Ranson, N.A., Ashcroft, A.E., Kippen, A.D., Vaughan, T.J., Radford, S.E., Lowe, D.C. Sci Rep