CATH Domain 4ly9B01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10490	Glucose-6-phosphate isomerase like protein; domain 1

Domain Context

CATH Clusters

Superfamily	Glucose-6-phosphate isomerase like protein; domain 1
Functional Family	Glucokinase regulatory protein

Enzyme Information

UniProtKB Entries (1)

GCKR_HUMAN

Homo sapiens

Glucokinase regulatory protein

PDB Structure

PDB	4LY9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors. Lloyd, D.J., St Jean, D.J., Kurzeja, R.J., Wahl, R.C., Michelsen, K., Cupples, R., Chen, M., Wu, J., Sivits, G., Helmering, J., Komorowski, R., Ashton, K.S., Pennington, L.D., Fotsch, C., Vazir, M., Chen, K., Chmait, S., Zhang, J., Liu, L., Norman, M.H., Andrews, K.L., Bartberger, M.D., Van, G., Galbreath, E.J., Vonderfecht, S.L., Wang, M., Jordan, S.R., Veniant, M.M., Hale, C. Nature