CATH Domain 3ptzE02

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.5	Single alpha-helices involved in coiled-coils or other helix-helix interfaces
	1.20.5.100	Cytochrome c1, transmembrane anchor, C-terminal

Superfamily	Cytochrome c1, transmembrane anchor, C-terminal
Functional Family	UDP-glucose 6-dehydrogenase

1.1.1.22

UDP-glucose 6-dehydrogenase.

based on mapping to UniProt O60701

UDP-glucose + 2 NAD(+) + H(2)O = UDP-glucuronate + 2 NADH.

-!- Also acts on UDP-2-deoxyglucose.

UGDH_HUMAN

Homo sapiens

UDP-glucose 6-dehydrogenase

PDB	3PTZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Role of Packing Defects in the Evolution of Allostery and Induced Fit in Human UDP-Glucose Dehydrogenase. Kadirvelraj, R., Sennett, N.C., Polizzi, S.J., Weitzel, S., Wood, Z.A. Biochemistry