CATH Domain 3h2qC00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.200	Superoxide dismutase, copper/zinc binding domain

Domain Context

CATH Clusters

Superfamily	Superoxide dismutase, copper/zinc binding domain
Functional Family	Superoxide dismutase [Cu-Zn]

Enzyme Information

1.15.1.1

Superoxide dismutase.

based on mapping to UniProt P00441

2 superoxide + 2 H(+) = O(2) + H(2)O(2).

UniProtKB Entries (1)

SODC_HUMAN

Homo sapiens

Superoxide dismutase [Cu-Zn]

PDB Structure

PDB	3H2Q
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS Seetharaman, S.V., Winkler, D.D., Taylor, A.B., Cao, X., Whitson, L.J., Doucette, P.A., Valentine, J.S., Carroll, M.C., Culotta, V.C., Hart, P.J. To be Published