CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.620 | HUPs |
Domain Context
CATH Clusters
| Superfamily | HUPs |
| Functional Family | Nicotinamide-nucleotide adenylyltransferase |
Enzyme Information
| 2.7.7.18 |
Nicotinate-nucleotide adenylyltransferase.
based on mapping to UniProt Q9HAN9
ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD(+).
|
| 2.7.7.1 |
Nicotinamide-nucleotide adenylyltransferase.
based on mapping to UniProt Q9HAN9
ATP + nicotinamide ribonucleotide = diphosphate + NAD(+).
-!- Nicotinate nucleotide can also act as acceptor. -!- See also EC 2.7.7.18.
|
UniProtKB Entries (1)
| Q9HAN9 |
NMNA1_HUMAN
Homo sapiens
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
|
PDB Structure
| PDB | 1KKU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis.
J.Biol.Chem.
|
