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CATH Superfamily 1.10.1440.10

Apolipoprotein C-II

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Apolipoprotein C-II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Apolipoprotein C-II

Structural domains comprising this superfamily share the structure of apolipoprotein C-II (apoC-II), a surface constituent of plasma lipoproteins and the activator for lipoprotein lipase (LPL) that is central for lipid transport in blood. Lipoprotein lipase is a key enzyme in the regulation of triglyceride levels in human serum PMID:10903476. The C-terminal helix of apoC-II is responsible for the activation of LPL PMID:12590574.

GO Diversity

Unique GO annotations
43 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
133 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 3
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 4
Function
Unique EC:
Unique GO: 43
Taxonomy
Unique Species: 133