CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1060 | Aconitase; Domain 2 |
|
3.40.1060.10 | Aconitase, Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Aconitase, Domain 2 |
| Functional Family | Aconitate hydratase, mitochondrial |
Enzyme Information
| 4.2.1.3 |
Aconitate hydratase.
based on mapping to UniProt P20004
Citrate = isocitrate.
-!- Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate. -!- The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate. -!- Cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate. -!- Formerly EC 4.2.1.4.
|
UniProtKB Entries (1)
| P20004 |
ACON_BOVIN
Bos taurus
Aconitate hydratase, mitochondrial
|
PDB Structure
| PDB | 8ACN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of aconitase with isocitrate and nitroisocitrate bound.
Biochemistry
|
