MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans.
Koch, A.W., Schiering, N., Melkko, S., Ewert, S., Salter, J., Zhang, Y., McCormack, P., Yu, J., Huang, X., Chiu, Y.H., Chen, Z., Schleeger, S., Horny, G., DiPetrillo, K., Muller, L., Hein, A., Villard, F., Scharenberg, M., Ramage, P., Hassiepen, U., Cote, S., DeGagne, J., Krantz, C., Eder, J., Stoll, B., Kulmatycki, K., Feldman, D.L., Hoffmann, P., Basson, C.T., Frost, R.J.A., Khder, Y.
Blood