CATH Domain 6qmkA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.120	6 Propeller
	2.120.10	Neuraminidase
	2.120.10.80	Kelch-type beta propeller

Domain Context

CATH Clusters

Superfamily	Kelch-type beta propeller
Functional Family	Kelch-like ECH-associated protein 1

Enzyme Information

UniProtKB Entries (1)

KEAP1_MOUSE

Mus musculus

Kelch-like ECH-associated protein 1

PDB Structure

PDB	6QMK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein Interaction. Heightman, T.D., Callahan, J.F., Chiarparin, E., Coyle, J.E., Griffiths-Jones, C., Lakdawala, A.S., McMenamin, R., Mortenson, P.N., Norton, D., Peakman, T.M., Rich, S.J., Richardson, C., Rumsey, W.L., Sanchez, Y., Saxty, G., Willems, H.M.G., Wolfe 3rd, L., Woolford, A.J., Wu, Z., Yan, H., Kerns, J.K., Davies, T.G. J.Med.Chem.