CATH Domain 6qm7G00

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.20	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
	3.60.20.10	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1

Superfamily	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Functional Family	Proteasome subunit alpha type

A4HN55	A4HN55_LEIBR Leishmania braziliensis Proteasome subunit beta
Q7JMX2	Q7JMX2_LEIIN Leishmania infantum Proteasome subunit alpha type

PDB	6QM7
External Links	PDBSum Proteopedia
Method	ELECTRON MICROSCOPY
Organism
Primary Citation	Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition. Wyllie, S., Brand, S., Thomas, M., De Rycker, M., Chung, C.W., Pena, I., Bingham, R.P., Bueren-Calabuig, J.A., Cantizani, J., Cebrian, D., Craggs, P.D., Ferguson, L., Goswami, P., Hobrath, J., Howe, J., Jeacock, L., Ko, E.J., Korczynska, J., MacLean, L., Manthri, S., Martinez, M.S., Mata-Cantero, L., Moniz, S., Nuhs, A., Osuna-Cabello, M., Pinto, E., Riley, J., Robinson, S., Rowland, P., Simeons, F.R.C., Shishikura, Y., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Viayna Gaza, E., Wall, R.J., Zuccotto, F., Horn, D., Ferguson, M.A.J., Fairlamb, A.H., Fiandor, J.M., Martin, J., Gray, D.W., Miles, T.J., Gilbert, I.H., Read, K.D., Marco, M., Wyatt, P.G. Proc.Natl.Acad.Sci.USA