CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
Superfamily | alpha/beta hydrolase |
Functional Family | Acetylcholinesterase |
Enzyme Information
3.1.1.7 |
Acetylcholinesterase.
based on mapping to UniProt P22303
Acetylcholine + H(2)O = choline + acetate.
-!- Acts on a variety of acetic esters. -!- Also catalyzes transacetylations.
|
UniProtKB Entries (1)
P22303 |
ACES_HUMAN
Homo sapiens
Acetylcholinesterase
|
PDB Structure
PDB | 6O5R |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase.
J.Biol.Chem.
|