CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

Q13467
FZD5_HUMAN
Homo sapiens
Frizzled-5

PDB Structure

PDB 6O39
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Raman, S., Beilschmidt, M., To, M., Lin, K., Lui, F., Jmeian, Y., Ng, M., Fernandez, M., Fu, Y., Mascall, K., Duque, A., Wang, X., Pan, G., Angers, S., Moffat, J., Sidhu, S.S., Magram, J., Sinclair, A.M., Fransson, J., Julien, J.P.
Proc. Natl. Acad. Sci. U.S.A.
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